Identifying colorectal cancer patients with Lynch syndrome (also known as hereditary non-polyposis colon cancer or HNPCC) makes an important difference in preventing further cancers for them and also for their family members. However, family or personal medical histories don’t always find everyone at risk.
One of every 35 patients with colorectal cancer has Lynch syndrome, and each one has at least three family members who carry a Lynch gene and will need more intensive polyp and cancer surveillance beginning when they are young adults.
Researchers at Ohio State University compared methods of testing colon tumors to screen for Lynch syndrome and predict those patients who need further genetic testing. They also looked at more traditional ways of finding potential Lynch syndrome, including family histories and age at diagnosis. Read the rest of this entry »



