Ask almost anyone after their first colonoscopy, and they’ll tell you, “The procedure was nothing, but the prep was awful.”

Now patients are reporting that combining MiraLAX®, an over-the-counter laxative, with 2 quarts of Gatorade tastes better and is easier to take than the standard 4-quart Golytely colonoscopy preparation. In a randomized clinical trial , almost 100 percent said they would repeat it again, compared to 1 out of 4 who wouldn’t take GoLYTELY® in the future.

In addition, doctors found no differences in how thoroughly the two preps clean the colon.

Splitting the dose between the night before the colonoscopy and the morning of the procedure did improve colon cleansing. But there was no difference in cleansing between split-dose GoLYTELY and split-dose MiraLAX with Gatorade. Read the rest of this entry »

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The first four sites where colorectal cancer patients can get regorafenib are now open.  Bayer Healthcare expects to open additional sites in the next two or three weeks.

Colorectal cancer patients whose cancer has gotten worse on all standard treatments can now be considered for the Regorafenib Extended Access program.

Bayer Healthcare has applied for FDA approval of regorafenib to treat colorectal cancer, but until it is actually approved and on the market, the expanded access program is the only way patients who might benefit can receive it.

Last fall, early results from the randomized Phase 3 CORRECT clinical trial showed colorectal cancer patients who received regorafenib lived longer than a similar group who got a placebo. Read the rest of this entry »

The FDA reminds patients who use fentanyl patches for pain to take special care storing, using, and discarding them.

Recently the FDA evaluated 26 cases of children’s accidents that involved the patches including 10 deaths and 12 hospitalizations. Sixteen children were under two years of age.

Problems included curious children finding patches in the trash or stored within their reach. In addition, loose patches transferred the potent narcotic medicine to children who were being held or carried. Even used patches can still contain significant amounts of fentanyl, enough to seriously hurt a child.

Before using either the brand name Duragesic® or generic fentanyl transdermal system patches, read the FDA approved Medication Guide. Read the rest of this entry »

Dole Fresh Vegetables is voluntarily recalling over 750 cases of DOLE® Seven Lettuces salad with Use-by Date of April 11, 2012.

While no illness has yet been associated with eating the salads, a random sample collected by the State of New York found contamination with Salmonella.

The recalled packages have a UPC code of 71430 01057 and Product Codes 0577N089112A and 0577N089112B.

Consumers should check the codes and the use-by date and throw out any suspicious salads. Retailers are being told to check shelves for any remaining Dole Seven Lettuce salads and remove them.

If you have questions, you can call the Dole Food Company Consumer Response Center at (800) 356-3111, which is open 8:00 am to 3:00 pm (PDT) Monday – Friday.

People with cancer or who are on chemotherapy should be especially careful to avoid foods that may carry bacteria. They have less healthy immune systems and can become seriously ill from Salmonella infections.  Young children and the elderly are also at risk for severe, sometimes life-threatening infections.

More information about Salmonella from the Centers for Disease Control.

Symptoms of salmonella infection include diarrhea, vomiting, and abdominal cramps that develop 12 to 72 hours after eating something contaminated by the bacteria. Most healthy adults recover without treatment, but severe cases may require a trip to the hospital and antibiotics.

When patients  were offered a choice of colorectal cancer screening with either FOBT or colonoscopy, they were significantly more likely to complete that screening than when their doctors recommended only FOBT or only colonoscopy.

Nearly 1000 racially and ethnically diverse patients in urban primary care practices were randomly assigned to get colorectal cancer screening via:

• Fecal occult blood testing (FOBT)
• Colonoscopy, or
• Their choice of either FOBT or colonoscopy.

Overall, 58 percent were screened within the next year.  Read the rest of this entry »