The counterfeit drug trade has reached global proportions, and solving the problem needs a global approach.

So says an editorial in this week’s The Lancet.

While the Avastin announcement last week raised lots of concern and media attention, the issue of counterfeit drugs isn’t new. In 2009, the European Union seized 34 million fake pills in just two months, including antibiotics, cancer drugs, and sildenafil (Viagra). Counterfeit medicines are a problem for both low and high income countries and can seriously hurt patients.

In January the FDA warned healthcare providers not to buy injectable cancer medications from “direct-to-clinic” promotions or non-verified sources. Such drugs, says the FDA, put patients at risk. Read the rest of this entry »

FDA Commissioner Margaret Hamburg announced yesterday during a teleconference that the FDA has arranged to meet critical needs for methotrexate and Doxil® (doxorubicin).

FDA has approved temporarily importing Lipodox, which has the same active ingredient — doxorubicin — and the same concentration as Doxil. There should be enough to meet needs for Doxil treatment.  FDA has inspected and approved the foreign plants that manufacture Lipodox.

APP Pharmaceuticals and Hospira both have ramped up production of methotrexate. Together they expect to be able to ship the drug immediately and have enough to meet future needs.  Methotrexate is especially needed by children with leukemia where it can produce remissions rapidly and cure most children with acute lymphoblastic leukemia (ALL).

Unfortunately, fluorouracil (5-FU) and leucovorin are still in shortage. Read the rest of this entry »

Would you like to know what top colon cancer experts recommend for diagnosing, treating, and following up colon cancer?

The National Comprehensive Cancer Network has just published NCCN Guidelines for Patients: Colon Cancer in an online version.

It’s simple to read. Just turn the pages like a book.

You can also download a PDF copy with an easy to use, clickable table of contents.

There is also more patient-focused information on a NCCN.com, a website for patients, caregivers, and families.

The Guidelines for Patients are based on NCCN Clinical Practice Guidelines in Oncology.  Updated frequently, the NCCN Guidelines are widely used by doctors to help them with making treatment decisions based on the latest evidence. Panels of oncologists, other health professionals, and advocates meet regularly to review new research and revise the guidelines to reflect it. Read the rest of this entry »

The Food and Drug Adminstration and Genentech have reported that counterfeit Avastin is being distributed in the United States. The counterfeit medicine does not contain
bevacizumab, Avastin’s active ingredient.

The packaging is different from genuine Avastin marketed here by Genentech. It includes a Roche logo which isn’t on the real drug, along with different codes.

Avastin is not in shortage now, and there are adequate supplies to meet the need.

Patients being treated with Avastin are urged to let their doctors know immediately if they have unusual symptoms. Read the rest of this entry »

Pat Steer

We are glad to welcome advocate Pat Steer to the Fight Colorectal Cancer Research and Treatment News.  She’s been living with stage IV rectal cancer since 2004.  A writer, she’s blogs about her life with cancer, training her beloved dogs, and her passion for good food at Life Out Loud.

Since my cancer diagnosis in 2004, my life has been full of choice and decisions. Cancer forces you to prioritize. Some days, it has seemed like cancer and treatment were calling all the shots in my schedule, changing my plans, and forcing decisions I didn’t want to have to make.

But I’ve made a few choices in the last eight years where I didn’t let cancer force my hand. I train and show dogs, and that’s very important to me. Early on, I decided to make attending my favorite dog shows a priority. I kept up my now-25-year tradition of camping with friends at a local show circuit. I entered a special event dog show held on New Year’s weekend, 2005 – three shows in 48 hours that wore me out, but was so worth the effort.  I covered Westminster in 2008 through 2010 for my column.

All of those decisions meant that sometimes I prioritized dog shows in spite of my treatment schedule. My oncologist, who once told me “I want you to live your life,” carefully moved my treatments around to accommodate the things I really wanted to do. After all, what good is surviving cancer if you can’t do the things you love? Read the rest of this entry »