Home Actor Luke Perry PSAs Actor Luke Perry PSAs Share on Facebook Share on LinkedIn Share on Twitter Copy this URL Share via Email Late Hollywood actor and Fight CRC celebrity ambassador Luke Perry became a colon cancer awareness advocate because of his childhood best friend Chad and wife Sheila, a stage IIIc survivor. His message: get screened. Colorectal cancer screening isn't embarrassing; it's lifesaving. Check out Luke's PSA's with Chad and Sheila below.