Teva has leucovorin calcium lyophilized powder 100 mg and 350 mg vials on back order and the company does not anticipate release until April 2011.
Bedford Laboratories also cites manufacturing delays but is “releasing product as it becomes available.”
Fusilev® (levoleucovorin) continues to be available from Spectrum Pharmaceuticals. However, special care needs to be taken with dosing. It cannot be substituted one-to-one for leucovorin. Patients need to be aware of its cost and the possibility that insurance may not cover its administration for colorectal cancer.
Previously: More Leucovorin Woes