Hand-Foot Syndrome Signals Xeloda Effectiveness

Posted by Kate Murphy on August 13th, 2011

Developing tender swelling or rash on their hands and feet may actually be good news for patients being treated with Xeloda® (capecitabine).

During a recent clinical trial, colorectal cancer patients with hand-foot syndrome lived longer, and it took longer for their cancer to get worse.

Researchers comparing two Xeloda-based chemotherapies for people with advanced colorectal cancer, studied skin side effects from both Xeloda and Erbitux® (cetuximab).  They found that about a third of patients experienced at least some hand-foot syndrome, and these patients lived almost 10 months longer than patients without skin changes. Read the rest of this entry »

Tall Women Have Higher Cancer and Colon Cancer Risk

Posted by Kate Murphy on August 9th, 2011

For every 10 centimeters (about 4 inches) increase in height, women have a 16 percent increase in their risk of cancer.

Taller women have an even greater risk for colon cancer — 25 percent for every 10 centimeters.  There is a 14 percent increased risk for rectal cancer.

There is about a 37 percent increase in the chance of getting any cancer between the shortest women (less than 5 feet, 1 inch) and the tallest (over 5 feet, 9 inches) according to a very large study in the United Kingdom. Read the rest of this entry »

Leucovorin shortage FAQ now available

Posted by Carlea Bauman on August 2nd, 2011

In response to the ongoing leucovorin shortage crisis, Fight Colorectal Cancer has created a Frequently Asked Questions document for patients.

The Fight CRC Answer Line (1-877-427-2111) has fielded over 100 calls from patients who were told they could not receive leucovorin due to a manufacturing shortage in the United States. Many patients, worried and confused, have had trouble determining their options if faced with this issue.

The FAQ addresses issues such as “What choices do I have if my doctor doesn’t have leucovorin?” andWhy is there a leucovorin shortage?”. It also directs patients to the Fight CRC online action center, where they can weigh in on the issue with their Members of Congress.

View and download the FAQ.

Extra Strength Tylenol Label Dose Reduced

Posted by Kate Murphy on July 28th, 2011

New labels for Extra Strength Tylenol® will reduce the maximum daily dose from 8 pills (4000 mg) to 6 pills (3000 mg).

Bottle of Extra Strength TylenolThe interval for taking the medicine will also change from 2 pills every 4 to 6 hours to 2 pills every 6 hours.

McNeil Consumer Healthcare, the makers Tylenol of announced the change to help prevent overdoses of acetaminophen.

Although acetaminophen is safe when used as directed, it is part of over 600 over-the-counter and prescribed medicines.  Maximum doses can be exceeded when people take several different medications at the same time, and too much acetaminophen can cause liver damage. Read the rest of this entry »

X-PECT Trial is Fully Enrolled

Posted by Kate Murphy on July 27th, 2011

The X-PECT phase III clinical trial has finished recruiting over 430 patients, evaluating perifosine treatment for patients with advanced colorectal cancer who have exhausted standard treatments.

The trial compares the effectiveness of adding perifosine to Xeloda® (capecitabine).

Led by Johanna Bendell, M.D., from the Sarah Cannon Research Institute in Nashville, TN, the trial is being conducted at 65 sites in the United States. Read the rest of this entry »

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