One of the major sites of tumor spread of colon cancer spread is the liver.

The liver can compensate for a long time despite having large tumors.  This is reason that our blood tests of liver function remain normal despite the liver having multiple lesions.  However, if the tumors grow to a certain size or interfere with the bile ducts, they can cause the liver enzymes. including the bilirubin, to increase. When bilirubin increases patients develop jaundice, indicating that the liver is not functioning well. Read the rest of this entry »