CEA Flares During Chemo Don’t Mean Cancer Progression

Posted by Kate Murphy on November 10th, 2009

Colorectal cancer patients whose CEA blood tests rise at the beginning of chemotherapy and then fall (CEA flare) do better than patients with a consistently rising CEA.   CEA flares don’t necessarily predict worsening cancer.

Compared to patients with consistently rising carcinoembryonic antigen (CEA), patients who had a CEA flare had more tumor shrinkage, longer time before their cancer got worse, and longer survival time. Read the rest of this entry »

Colorectal Cancer News in Brief: July 10

Posted by Kate Murphy on July 10th, 2009

Research this week finds FDG/PET able to predict response to chemotherapy even after one treatment, and chemotherapy before surgery for liver mets makes CT scan evaluation less accurate.

Finding the best imaging methods to diagnosis and monitor cancer and comparing new colorectal cancer screening technologies to current standards are among recommended priorities for comparative effectiveness research (CER).  The FDA reports new egg safety rules and the recall of a powdered dietary supplement.

Videos of cancer patients are now online discussing the emotional impact of their diagnosis in The Day I Found Out. Read the rest of this entry »

Response to Chemo Before Liver Met Resection Doesn’t Predict Survival

Posted by Kate Murphy on June 16th, 2009

Patients who had tumors shrink in response to chemotherapy given before they had surgery for colorectal cancer that had spread to their livers had no better long-term survival than patients whose cancer remained the same or even got worse.

Doctors in New York followed 111 patients who had chemotherapy before surgery to remove liver metastases (neoadjuvant chemotherapy). After five years of follow-up, median overall survival was 62 months.  Overall survival was similar in three different groups:  those who had a complete or partial response to neoadjuvant chemotherapy, those whose tumors remained stable, and those whose cancer progressed during chemotherapy. Read the rest of this entry »

Ginger Helps Relieve Chemo Nausea

Posted by Kate Murphy on May 25th, 2009

Adding ginger capsules to standard treatment for chemotherapy nausea reduced nausea and vomiting from chemotherapy.

Patients who got ginger (Zingiber Officinale) in capsules twice a day for three days before chemo and three days after reported significantly less nausea that those who were treated with placebo.  All patients in the study also received standard anti-nausea therapy on the day of chemo.

Almost 650 patients, mostly women, were randomly assigned to ginger supplements or a placebo in a blinded trial that will be reported at the 2009 ASCO annual meeting. Read the rest of this entry »

What to Do When the Kidney Does Not Function Well

Posted by Heinz-Josef Lenz, MD on April 2nd, 2009

We need to monitor not only for liver function but also for kidney function. However kidney problems are much less frequent.

Patients who undergo chemotherapy know that every time they receive chemotherapy, oncologists take blood to test for blood counts and also for liver and kidney function. Read the rest of this entry »

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