Avastin Effective for Older Patients

Colorectal cancer patients 65 and older without other serious medical problems benefitted when Avastin® (bevacizumab) was added to chemotherapy. Combining results of four randomized clinical trials of Avastin and chemotherapy in patients with advanced colorectal cancer, researchers found that adding Avastin increased both the time older patients lived and the time before their cancer got worse.…  Read More

CEA Flares During Chemo Don't Mean Cancer Progression

Colorectal cancer patients whose CEA blood tests rise at the beginning of chemotherapy and then fall (CEA flare) do better than patients with a consistently rising CEA.   CEA flares don’t necessarily predict worsening cancer. Compared to patients with consistently rising carcinoembryonic antigen (CEA), patients who had a CEA flare had more tumor shrinkage, longer time before…  Read More

Colorectal Cancer News in Brief: July 10

Research this week finds FDG/PET able to predict response to chemotherapy even after one treatment, and chemotherapy before surgery for liver mets makes CT scan evaluation less accurate. Finding the best imaging methods to diagnosis and monitor cancer and comparing new colorectal cancer screening technologies to current standards are among recommended priorities for comparative effectiveness research…  Read More

Response to Chemo Before Liver Met Resection Doesn't Predict Survival

Patients who had tumors shrink in response to chemotherapy given before they had surgery for colorectal cancer that had spread to their livers had no better long-term survival than patients whose cancer remained the same or even got worse. Doctors in New York followed 111 patients who had chemotherapy before surgery to remove liver metastases (neoadjuvant…  Read More

Ginger Helps Relieve Chemo Nausea

Adding ginger capsules to standard treatment for chemotherapy nausea reduced nausea and vomiting from chemotherapy. Patients who got ginger (Zingiber Officinale) in capsules twice a day for three days before chemo and three days after reported significantly less nausea that those who were treated with placebo.  All patients in the study also received standard anti-nausea therapy…  Read More

Adding Erbitux to First Line Chemotherapy with Avastin Hurts More than Helps

Adding Erbitux to standard first line treatment for colorectal cancer of CAPOX with Avastin doesn’t help.  In fact, patients who receive the additional agent have a shorter time until their cancer gets worse and have worse side effects. Results of a randomized phase III clinical trial that added the monoclonal antibody Erbitux® (cetuximab) to Xeloda® (capecitabine),…  Read More