ACA Mandates Insurance Coverage for Clinical Trials

By January 1, all insurers will be required to cover routine care for patients enrolled in clinical trials. (Typically any experimental care is provided at no cost to the patient.) “This should be seen as a step forward for the U.S. oncology community,” wrote Dr….

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Colon Cancer Prevention Trial Seeking New Patients

Can drugs used to help lower cholesterol also keep colon cancer from returning?  Researchers at the National Surgical Adjuvant Breast and Bowel Project (NSABP) are seeking patients for a one-year clinical trial to determine if cholesterol-lowering drugs (statins) might help prevent the growth of precancerous (adenomatous)…

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National polyp prevention trial needs participants

Do cholesterol-lowering drugs help prevent CRC? You might be able to help answer that question. A national research project needs people who have been treated for early-stage (stage I or II) colorectal cancer in the past year. There have been tantalizing hints that cholesterol-lowering drugs…

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X-PECT Trial is Fully Enrolled

The X-PECT phase III clinical trial has finished recruiting over 430 patients, evaluating perifosine treatment for patients with advanced colorectal cancer who have exhausted standard treatments. The trial compares the effectiveness of adding perifosine to Xeloda® (capecitabine). Led by Johanna Bendell, M.D., from the Sarah…

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CRC Groups Join Together to Offer Clinical Trial Matching

Leading colorectal cancer advocacy organizations Colon Cancer Alliance and Fight Colorectal Cancer announced that they are teaming up on an initiative to encourage patients with colorectal cancer to take charge of their diagnosis and learn about clinical trials. The Colorectal Cancer Clinical Trial Call to…

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Hedgehog Fails to Help Advanced Colorectal Cancer Patients

In disappointing news, adding the Hedgehog inhibitor GDC-0449 to standard chemotherapy failed to increase the time before advanced colorectal cancer got worse. Researchers compared progression-free survival between patients who got either FOLFOX or FOLFIRI chemotherapy with Avastin and a group who got the same chemo…

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No Benefit Adding Cetuximab to Chemo for Stage III Colon Cancer

Adding Erbitux® (cetuximab) to standard chemotherapy for stage III colon cancer didn’t improve patient outcomes and added more side effects. All of the patients in the NO147 trial had cancer that had spread to their lymph nodes and had surgery before beginning chemotherapy. They had…

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Clinical Trial at NIH for Unresectable Liver Tumors

Patients with liver tumors, including those that have spread from colorectal cancer, can enroll in a clinical trial at the National Institutes of Health Clinical Center in Bethesda. The trial will test the effectiveness of infusing the drug melphalan through the artery that feeds the…

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