National polyp prevention trial needs participants

  Do cholesterol-lowering drugs help prevent CRC? You might be able to help answer that question. A national research project needs people who have been treated for early-stage (stage I or II) colorectal cancer in the past year. There have been tantalizing hints that cholesterol-lowering drugs (statins) might help prevent the growth of precancerous (adenomatous) polyps…  Read More

New Trial Looks to Reduce Recurrence and Neuropathy for Stage III Patients

If you are diagnosed with stage III colon cancer, you will probably receive about six months of treatment with FOLFOX after surgery. Research shows that this treatment regimen helps prevent recurrence for some – but not all – patients with stage III colon cancer.  A clinical trial has been launched to answer two questions about this…  Read More

X-PECT Trial is Fully Enrolled

The X-PECT phase III clinical trial has finished recruiting over 430 patients, evaluating perifosine treatment for patients with advanced colorectal cancer who have exhausted standard treatments. The trial compares the effectiveness of adding perifosine to Xeloda® (capecitabine). Led by Johanna Bendell, M.D., from the Sarah Cannon Research Institute in Nashville, TN, the trial is being conducted…  Read More

CRC Groups Join Together to Offer Clinical Trial Matching

Leading colorectal cancer advocacy organizations Colon Cancer Alliance and Fight Colorectal Cancer announced that they are teaming up on an initiative to encourage patients with colorectal cancer to take charge of their diagnosis and learn about clinical trials. The Colorectal Cancer Clinical Trial Call to Action campaign matches colorectal cancer patients with currently recruiting clinical trials…  Read More

Help Answer Questions About Exercise after Colon Cancer Treatment

Are you done — or almost done — with your treatment for colon cancer? Will you help answer a question about how to help colon cancer survivors  increase their physical activity? You’ll learn more about colon cancer and may be randomly assigned to a special interactive program that is designed to help recovering colon cancer patients…  Read More

Hedgehog Fails to Help Advanced Colorectal Cancer Patients

In disappointing news, adding the Hedgehog inhibitor GDC-0449 to standard chemotherapy failed to increase the time before advanced colorectal cancer got worse. Researchers compared progression-free survival between patients who got either FOLFOX or FOLFIRI chemotherapy with Avastin and a group who got the same chemo regimen with GDC-0449. There was no difference