Stage III Cetuximab Trial Closed

It doesn’t help patients to add Erbitux to FOLFOX chemotherapy after surgery for stage III colon cancer a data monitoring committee for a clinical trial testing the new treatment has decided. Because the analysis showed that patients were not benefiting from adding Erbitux to FOLFOX…

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Test of Vaccine Against Colon Cancer Underway

Scientists at the University of Pittsburgh are testing a vaccine to recognize a protein in colon polyps and trigger the immune system to destroy them. MUC1 is a protein found in precancerous colorectal polyps and in colon cancer. The experimental vaccine causes the body’s immune…

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Phase III Sutent Trial for Colorectal Cancer Discontinued

Pfizer announced yesterday, June 30, 2009, that they are discontinuing a phase III trial comparing FOLFIRI chemotherapy alone to FOLFIRI with added Sutent® (sunitinib). Based on results so far, the independent Data Monitoring Committee (DMC) determined that a significant reduction in progression-free survival was not…

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Clinical Trial Open: Tomotherapy for Limited Cancer Mets

Cancer patients with only a few tumors that have spread to other parts of their bodies (metastases) will be part of a clinical trial to test precisely focused, high-dose radiation treatment called helical tomotherapy. Researchers at the National Institutes of Health Clinical Center want to…

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How to Treat Rectal Cancer after Surgery? A Clinical Trial

Focus on Clinical Trials Can adding Avastin® (bevacizumab) to FOLFOX therapy after surgery and presurgical chemoradiotherapy reduce recurrence and improve survival for patients with rectal cancer? A clinical trial to answer this question is underway and is looking for participants.  Led by a team of…

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Clinical Trial: Vaccine Therapy after Surgery

Can the body develop an immune response that will destroy cancer cells in the body and prevent cancer from returning after surgery to remove metastatic tumors?  If it can, what’s the best way to do that? Researchers are studying vaccines and immune response in patients…

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Clinical Trial Testing Ultrasound System for Painful Bone Mets

Cancer that has spread to the bone can be excruciatingly painful.  Currently radiation treatment or opiate drugs are used to manage pain, but these are not always successful. A system that combines magnetic resonance imaging (MRI) with ultrasound treatment to destroy bone tumors and treat…

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