Tag Archives: colorectal cancer prevention

Test of Vaccine Against Colon Cancer Underway

Scientists at the University of Pittsburgh are testing a vaccine to recognize a protein in colon polyps and trigger the immune system to destroy them. MUC1 is a protein found in precancerous colorectal polyps and in colon cancer. The experimental vaccine causes the body’s immune system to develop antibodies against MUC1, killing tissue that contains it and potentially preventing polyps from returning.

Two Colonoscopies Better at Predicting Future Polyp Risk

Results from two colonoscopies three years apart gave better information about whether a high-risk polyp would be found on a third exam than results from the second test alone. Even if a second colonoscopy, done three years after the first, showed no adenomas at all, 8 in 100 study participants with high-risk polyps on their first exam had developed a high-risk polyp by six years when they had a third colonoscopy.

Colorectal Cancer Rates Increasing Worldwide

As nations develop economically and adopt more Western diet and lifestyle, colorectal cancer increases.  In fact, the United States is the only nation in the world where colorectal cancer incidence rates are falling for both men and women. Over the past 20 years, colorectal cancer rates have risen in 27 of 51 countries including Eastern Europe, most of Asia, and some South American countries.  Rates for men are rising faster than those for women.

Colon and Rectal Cancers Increasing in Young People

Although the numbers of new colon and rectal cancers have been steadily declining in people over 50, the rate of newly diagnosed cancer is increasing in young adults from 20 to 49  in the United States. The increase is primarily driven by rectal cancer in non-Hispanic whites where there was an average annual increase of 3.5 percent in men and 2.9 percent in women from 1992 through 2005.  Overall, incidence of colorectal cancer in young adults rose during that time 1.5 percent in men and 1.6 percent in women each year, almost all of the new cancers diagnosed in the left colon (distal colon) or rectum.

Black Raspberries Reduce Colorectal Inflammation and Polyps

Several studies presented during the 2008 Frontiers in Cancer Prevention Research meeting sponsored by the American Association for Cancer Research found black raspberries had a positive impact on colorectal cancer development. Freeze-dried berries reduced the inflammation that contributes to colorectal cancer in both humans and mice, the number of tumors in mice, and new rectal polyps in patients with familial adenomatous polyposis.  After treatment with berries, levels of proteins that control inflammation were reduced in patients with colorectal cancer.

Vitamin D Reduces Risk for Colon Polyps

Both the level of vitamin D in the blood and intake of vitamin D-rich foods decrease the risk of colorectal polyps in a number of studies. Analyzing published studies of blood levels of vitamin D, researchers found a 30 percent decrease in the risk of adenomas among people with the most circulating vitamin D compared to those with the least.  The highest vitamin D intake decreased adenomatous polyp risk by 11 percent.

No Connections Between Acrylamide and GI Cancers

Acrylamide is produced when carbohydrate-rich foods are cooked at high temperatures.  Foods like french fries, potato chips, cakes, and even coffee contain high levels of acrylamide.  It has been classified as a “probable” carcinogen based on animal studies where cancer resulted from very high doses.  However, human studies have not always produced clear answers. Epidemiologists in The Netherlands had people fill out food questionnaires based on common Dutch foods that contained acrylamide.  Thirteen years later, they found no increase in the number of colorectal or other gastrointestinal cancer  in those people who ate foods with high amounts of acrylamide.

Make a Video to Encourage Screening

Do you have a secret yen to be a moviemaker?  Star in your own video?  Help people learn that screening saves lives? End Colon Cancer Now. Org at the Fred Hutchinson Cancer Center is looking for a short creative videos to spread the colorectal cancer screening message.  The top video in the Get Screened Contest will win $2,500.

President's Cancer Panel Recommends National Priority for Cancer

In a new report Maximizing Our Nation’s Investment in Cancer:Three Crucial Actions for America’s Health the President’s Cancer Panel makes three recommendations to the President that they feel are critical to the battle against cancer in the United States. Make reducing the cancer burden a national priority. Ensure that all Americans have timely access to needed health care and disease prevention measures. End the scourge of tobacco in the United States.

C3 Advocate Brings Laughter to CRC Prevention

Standup comic Brenda Elsagher was once voted the funniest woman in the Twin Cities.  Calling her doctor the “rear admiral”, she’s featured in a TV report on colorectal cancer on WCCO, Minneapolis talking about the importance of colonoscopies and colorectal cancer prevention. Brenda is a research advocate for C3 and weaves colorectal cancer prevention and survivorship messages into her comedy routines, her motivational speaking, and a regular blog. Diagnosed in her thirties, Brenda has a colostomy that she talks about freely and with humor.  In If the Battle is Over Why am I Still in Uniform: Humor as a Survival Tactic to Combat Cancer she discusses her journey with colon