Tag Archives: colorectal cancer risk

No Benefit for Multivitamins in Preventing Women's Colorectal Cancer

Regular use of multivitamins didn’t reduce risk for colorectal and other cancers in a diverse group of 162,000 women from sites across the United States.  After eight years of follow-up, there was no significant difference in cancer, heart disease, or death between multivitamin users and those who didn’t take the supplements.

Online Tool Predicts Individual Colorectal Cancer Risk

Average risk men and women and their doctors can estimate the probability of that individual developing colon or rectal cancer by using an interactive tool available online.  Developed by National Cancer Institute, the model is based on population research and cancer incidence information. In developing the prediction tool, researchers matched 1,600 men and women with colon cancer and 650 with rectal cancer to nearly 1,900 similar individuals without cancer.   Using identified risk factors for colorectal cancer, they were able to estimate the probability than an individual would develop colon or rectal cancer within the next 5, 10, or 20 years.  The prospective National Institute of Health-American Association of Retired Persons

Metabolic Syndrome Increases Colorectal Cancer Risk

People with a combination of three common medical conditions together known as metabolic syndrome have a greatly increased risk of colorectal cancer.  The three are hypertension, diabetes and elevated cholesterol. Reviewing answers the the National Health Interview Survey, researchers found that people who reported metabolic syndrome conditions were almost twice as likely to have colorectal cancer.  Nearly 58,000 people were interviewed by the NHIS in 2002-2003.  Of those 1,200 had metabolic syndrome and 350 had been diagnosed with colorectal cancer. 

Gene Variation Reduces Colorectal Cancer Risk

People with a variation in the gene that controls how fat is metabolized by cells have a lowered chance of getting colorectal cancer, even in families with already increased risk. Scientists studied differences in short regions of the ADIPOQ gene called single nucleotide polymorphisms (SNPs) among patients with colorectal cancer and a similar group of people who didn’t have cancer. In two different study groups, they found that one variation reduced risk of getting cancer by about 30 percent.

Alcohol Increases Colorectal Cancer Risk

Drinking increases risk for colorectal cancer, but the type of alcoholic drinks don’t appear to make a difference.  Instead, danger seems to come from the alcohol itself rather than other ingredients. In the Netherlands Cohort Study on diet and cancer,  alcohol consumption and specific alcoholic drinks were studied for more 2,300 people who had colon or rectal cancer. Compared to people who did not drink at all, there was a 30 percent increase in colorectal cancer among people who had 3 or more alcoholic drinks a day.

Urologic Cancer Increases Risk for Colorectal Cancer

A previous diagnosis of ureter or kidney cancer increases the risk for colorectal cancer, especially when the diagnosis was made before the age of 60.  In addition, colorectal cancer increases risk for certain urologic cancers. Cancer in the ureter or renal pelvis (urothelial cancer) was most strongly associated with later colorectal cancer with only a small increased risk with diagnoses of bladder cancer or cancer in other parts of the kidney.