Virtual Colonoscopy Effective Screening Method

Posted by Kate Murphy on September 23rd, 2008

Computerized tomographic colonography (CTC), so-called virtual colonoscopy, proved accurate in locating colon polyps or cancers 10 millimeters or larger in a large study conducted in a number of community centers across the United States.  The x-ray-based test found 90 percent of l0 millimeter polyps identified by traditional colonoscopy, which uses a lighted tube inserted into the rectum to view the colon. Read the rest of this entry »

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Screening Methods

Posted by Kate Murphy on February 29th, 2008

Comparing Screening Methods for Average Risk Patients

Tests that Detect Adenomatous Polyps and Cancer


Colonoscopy

  Every 10 years  

Most sensitive test for small and large polyps and cancers. Examines the entire colon, polyps can be removed and biopsied during the procedure.

 

Expensive, requires complete bowel cleansing. Normally uses sedation and requires someone to accompany patient, Rare instances of bowel perforation and bleeding. May not be covered by insurance.

Double-contrast barium enema

 

Every 5 years

 

Visualizes the entire colon, can detect most cancers, and the majority of large polyps. Helps patients who cannot complete a colonoscopy or where colonoscopy is not medically appropriate. Less expensive.

 

Requires complete bowel preparation. May be uncomfortable. An experienced radiologist is critical to quality exam. Colonoscopy is still required to biopsy lesions or removed polyps.

CT-colonography (virtual colonoscopy)

 

Every 5 years

 

Does not require sedation. No recovery time, patients can drive home or return to work. Finds cancer and large polyps at the same rate as colonoscopy. May find problems outside the colon as well.

 

Requires complete bowel preparation. Colonoscopy is required to biopsy and remove polyps. Technology and radiologist training are growing but not complete. May not detect non-polypoid colorectal neoplasms. May not be covered by insurance. False-positive problems identified outside the colon may require unnecessary follow-up tests.

Flexible sigmoidoscopy

 

Every 5 years

 

Can be done by primary care physician or trained nurse practitioner. Does not require sedation

 

Will miss polyps or cancers in the right colon beyond the reach of the scope. If polyps are found, colonoscopy and addition bowel preparation are required. Can be uncomfortable.

Tests that Primarily Detect Cancer


gFOBT: Guaiac-based stool test

 

Every year

  Inexpensive, is done privately at home, can be offered to many people through community programs, including those without primary care or insurance.  

Not very sensitive to polyps, will miss some cancers. Needs to be done correctly over three days. Requires diet and drug restrictions. Patients must handle stool. Has a high false positive rate that requires follow-up colonoscopy for about 1 in 3 tests.

FIT: Immunochemical stool test

  Every year   Has no diet or drug restrictions prior to the test. Limits blood detected to the colon and rectum . Is more sensitive than  guaiac-based tests for cancer. May be simpler for patients to do.

 

Will miss some cancers and most advanced polyps. More expensive than gFOBT. All positive tests require colonoscopy follow-up.

Stool DNA test   Not yet known  

Done at home privately. Not necessary to handle stool. Collection kit shipped directly to patient. No special diet prep required.

 

May not find all cancers or large polyps. Requires prompt, ice-pack shipment to special labs. Significantly more expensive than gFOBT or FIT. Colonoscopy follow-up necessary for positive test.

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