Depression Drug May Ease Peripheral Neuropathy Pain

The antidepressant drug Duloxetine (Cymbalta®) was shown in a recent study to provide pain relief to people suffering from peripheral neuropathy caused by chemotherapy. Chemotherapy drugs such as oxaliplatin (Eloxatin®, used in the FOLFOX regimen for colorectal cancer) can damage “peripheral” nerve cells (those beyond the brain and spinal cord), causing pain, tingling, numbness especially in…  Read More

Highlights from ASCO 2011

While there weren’t new blockbuster announcements for colorectal cancer this year at the American Society for Clinical Oncology’s (ASCO) Annual Meeting, there was plenty of focus on making what we already have work better and on choosing the patients who will benefit the most from treatments, as well as those who might not be helped at…  Read More

XELOX Beats 5-FU with Fewer Recurrences

A combination of Xeloda and Eloxatin (XELOX) was better than standard 5-FU and leucovorin chemotherapy in reducing recurrences of stage III colon cancer after surgery.  Significantly more patients receiving XELOX were alive without cancer three years after treatment began. Roche announced results of a Phase III clinical trial that compared XELOX chemotherapy to bolus 5-FU and…  Read More