Tag Archives: FIT

FDA approves first non-invasive DNA test for colorectal cancer

Big news in the colorectal cancer prevention and screening community yesterday! In a never-before-seen move, the Food & Drug Administration (FDA) and Centers for Medicare & Medicaid Services (CMS) jointly proposed Cologuard as a new option for colorectal cancer screening. What is Cologuard? Cologuard, produced by Exact Sciences, is a non-invasive (not requiring insertion of instruments into the body), stool-based (you test your poo) DNA test designed to analyze the presence of blood and certain DNA mutations in a patient’s stool sample that can indicate cancer and/or precancerous polyps. Cells of DNA are released into the stool continuously as part of the digestive process. There are already at-home screening options

Colorectal Cancer Is (or Could Be) the Poster Child for Cancer Prevention

February is Cancer Prevention Month, and colorectal cancer (CRC) is a poster child, as one of the few cancers that can be literally seen and removed before it becomes cancer, or can be caught early enough in regular screening to be literally cured. Ponder these facts, based on 20 years of experience and summarized by Linda Rabeneck, MD, MPH of Cancer Care Ontario at the recent “GI-ASCO” (Gastrointestinal Cancers Symposium of the American Society of Clinica Oncology):   Annual stool tests (fecal occult blood test, or FOBT) reduce deaths from colorectal cancer by 15 to 33 percent. The newer FIT stool test (fecal immunochemical test) appears to be even better than the

FIT Beats All Other Screening for Effectiveness and Cost

In a computer simulation, FIT — fecal immunochemical testing — done every year saved more lives and cost the least of any colorectal cancer screening method, including colonoscopy. The computer model looked at 100,000 average risk people and compared screening methods results for number of colorectal cancer cases number of colorectal cancer deaths cost of screening and treating colorectal cancer for each screened person Compared to not screening at all, annual FIT  could save 3 out of 4 deaths from colorectal cancer. For every 100,000 people between 50 and 75, nearly 3,500 people wouldn’t get colorectal cancer, and over 1,300 wouldn’t die. Not only did FIT screening save the most

Many Doctors Doing Colorectal Cancer Screening Wrong

FOBT screening saves lives, but only when it is done right. Three out of four primary care doctors did a fecal occult blood test once during an office visit, a method that is ineffective in finding cancer or preventing death from colorectal cancer. One out of four used the in-office test exclusively. Less than half of doctors had a system in place to be sure that home tests were completed and returned. 

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