Patients who had tumors shrink in response to chemotherapy given before they had surgery for colorectal cancer that had spread to their livers had no better long-term survival than patients whose cancer remained the same or even got worse.
Doctors in New York followed 111 patients who had chemotherapy before surgery to remove liver metastases (neoadjuvant chemotherapy). After five years of follow-up, median overall survival was 62 months. Overall survival was similar in three different groups: those who had a complete or partial response to neoadjuvant chemotherapy, those whose tumors remained stable, and those whose cancer progressed during chemotherapy. Read the rest of this entry »