Hypertension Clue to Better Outcomes with Avastin

Patients who developed hypertension with Avastin® (bevacizumab) had better response to treatment for colorectal cancer.  More had tumors shrink, and it took significantly longer for their cancer to get worse. In a small Italian study, researchers measured blood pressure in 39 patients receiving Avastin along…

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Stents Can Manage Colon Obstruction Effectively

Self-expanding metal stents can help patients with an obstruction from advanced colon cancer avoid surgery. When a large tumor blocks the left side of the colon, surgeons can remove the tumor or put in a stent to move bowel contents around the obstruction.  According to…

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Two Different First-Line Irinotecan Treatments Have Similar Results

Spanish researchers have found that patients treated every week with Camptosar® (irinotecan, CPT-11) plus a high dose of  continuous infusion 5-FU (fluorouracil) without leucovorin had similar outcomes to those treated with the more common biweekly FOLFIRI treatment that includes leucovorin.  FOLFIRI is Camptosar, 5-FU, and…

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Call for New Staging System for Advanced Colorectal Cancer

Experts in treating colorectal cancer that has spread to distant sites say that the need for a better staging system for advanced disease is urgent. More specific staging could identify patients whose cancer could be cured with surgery.  For others, modern chemotherapy might make curative…

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Xelox as Effective as FOLFOX after Colorectal Cancer Progresses

XELOX, as second-line therapy, was found to be as effective as the more commonly used FOLFOX treatment for patients whose cancer had already gotten worse on treatment with Camptosar® (irinotecan). XELOX combines an oral drug Xeloda® (capecitabine) with Eloxatin® (oxaliplatin).  FOLFOX uses an infusional schedule…

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