Although being obese increases risk for most colon and rectal cancers, the connection isn’t true in all types of colorectal cancer.
Cancers that are linked to microsatellite instability (MSI) don’t appear to be influenced by obesity, strengthening the belief that MSI cancers come about differently than the average colorectal cancer.
Overall, in a recent study, body mass index and weight gain during adult life increased risk of colorectal cancer by about 30 percent for men and 20 percent for women. However, increased risk was limited to microsatellite stable or microsatellite low tumors. Read the rest of this entry »