Picoplatin Effective for CRC with Less Neuropathy

Picoplatin can be as effective as oxaliplatin as an initial treatment for advanced colorectal cancer but has less neuropathy. Updated information comparing picoplatin in combination with 5-FU and leucovorin (FOLPI) to the standard oxaliplatin treatment (FOLFOX) found similar response rates.  About half of patients on both treatments were alive a year later.  However, there was significantly…  Read More

Colorectal Cancer News in Brief: November 7

Briefly Patients with diabetes aren’t any more likely to develop neuropathy in hands and feet when treated with oxaliplatin. Learn more about  current colorectal cancer prevention and treatment at a Memorial Sloan Kettering CancerSmart workshop on November 12.  NIH has a downloaded booklet on palliative care, and Oncology on Canvas is looking for artwork from cancer…  Read More

Calcium and Magnesium Infusions Reduce Neurotoxicity with Oxaliplatin

Update from 2008 ASCO Meeting in Chicago A study presented during the American Society of Clinical Oncology meeting showed that adding IV infusions of calcium and magnesium to oxaliplatin treatment reduced peripheral neuropathy. Eloxatin® (oxaliplatin) is part of the FOLFOX treatments for colorectal cancer.  As doses accumulate, patients begin to experience tingling and numbness in their…  Read More