Picoplatin can be as effective as oxaliplatin as an initial treatment for advanced colorectal cancer but has less neuropathy.
Updated information comparing picoplatin in combination with 5-FU and leucovorin (FOLPI) to the standard oxaliplatin treatment (FOLFOX) found similar response rates. About half of patients on both treatments were alive a year later. However, there was significantly less neuropathy overall with FOLPI and no severe neuropathy.
FOLPI did have substantially more serious problems with lowered blood counts than FOLFOX. Read the rest of this entry »