Uninsured with Rectal Cancer are More Likely to Die

Insurance makes a difference for people with rectal cancer. Rectal cancer patients without insurance or covered by Medicaid are almost twice as likely to die within five years as those privately insured. Not only are they diagnosed at a later stage, but fewer receive recommended treatments at every stage. More than half of the difference between…  Read More

DNA Mismatch Repair and 5-FU: What's the Connection?

Some colon cancer patients don’t benefit from treatment with 5-FU based chemotherapy and may even have worse outcomes than if they no chemo at all. Of every 100 people with colon cancer, about 15 will have cancers that arise when mistakes in DNA during cell division are not caught and fixed.  Scientists call this defective mismatch…  Read More

Tumor Mutation Predicts Poor Prognosis in Stage I-III Colon Cancer

By studying changes in tumor tissue from colon cancer patients whose cancers had not spread to distant organs, researchers were able to isolate a gene mutation that led to a poor outcome. Stage I through III colon cancer patients whose tumors had a mutation in the PIK3CA gene were more likely to die of colon cancer…  Read More