Laparoscopic Surgery a Safe Choice for Rectal Cancer

In the hands of experts, laparoscopic surgery for rectal cancer was as successful as an open abdominal operation.  Cancer free survival after five years wasn’t any different, and cancer was no more likely to return in and around the rectum. Even if surgeons had to change their approach during the operation and convert from laparoscopic to…  Read More

Aspirin Saves Lives after Colon Cancer Treatment

Colorectal cancer patients with early stage disease were 30 percent less likely to die from cancer and 20 percent less likely to die at all if they took aspirin regularly after their diagnosis. Benefit was even greater for those who began taking the medicine for the first time after their diagnosis. However, only the group whose…  Read More

Early Tumor Shrinkage Points to Good Erbitux Outcomes

Patients with advanced colorectal cancer whose tumors have gotten smaller six weeks after starting treatment with Erbitux had a much longer time before their cancer got worse and almost twice the overall survival as patients whose tumors didn’t shrink. Patients in the BOND study had already gotten worse on standard chemotherapy and were receiving either Erbitux®…  Read More

Lack of Insurance Impacts Survival in CRC Patients Under 65.

Not having insurance reduces the chance that someone with colorectal cancer will live a year after their diagnosis.  Even when patients from 18 to 64 have other illnesses, their insurance status makes a difference in survival. Risk of dying during that first year was 50 to 90 percent higher among the uninsured.  They were more likely…  Read More

Adding Irinotecan to Infusional 5-FU Does Not Add Benefit for Stage III Colon Cancer

Five years after surgery, there was no improvement in either disease-free survival or overall survival when irinotecan was added to standard 5-FU treatments delivered via continous infusion for patients with stage III colon cancer.  Adding irinotecan increased the rate of serious side effects. The PETACC-3  (Pan European Trial Adjuvant Colon Cancer)  trial was designed to see if…  Read More

Tumor Mutation Predicts Poor Prognosis in Stage I-III Colon Cancer

By studying changes in tumor tissue from colon cancer patients whose cancers had not spread to distant organs, researchers were able to isolate a gene mutation that led to a poor outcome. Stage I through III colon cancer patients whose tumors had a mutation in the PIK3CA gene were more likely to die of colon cancer…  Read More