We have learned that we can prevent colon cancer by taking aspirin. However because of the significant side effects such as gastric ulcer, bleeding complications and kidney problems, aspirin is not recommended for the public to prevent colon cancer.
In an effort to prevent colon cancer but avoid the side effects of aspirin, COX-2 inhibitors such as Celebrex® (celecoxib) was developed and tested to see if they could prevent colon cancer without the side effects of aspirin. Unfortunately, we have witnessed that high doses of Celebrex can cause heart attacks which put a significant hold on the development of these drugs as chemopreventative agents. Read the rest of this entry »