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S1613, Trastuzumab and Pertuzumab or Cetuximab and Irinotecan Hydrochloride in Treating Patients With Locally Advanced or Metastatic HER2/Neu Amplified Colorectal Cancer That Cannot Be Removed by Surgery

Estado del programa

Activo, no recluta

Fase

Fase 2

Inmunoterapia previa permitida

Sí

Ensayo dirigido por el CRC

Sí

Drogas

cetuximab, HER-2 testing, Irinotecan Hydrochloride, Pertuzumab, Trastuzumab, Camptosar, Erbitux, Herceptin, Perjeta

Etiquetas

MSS/ MMRp

Comentarios

Patients with HER2/neu amplified colorectal cancer that has spread from where it started to other places in the body and cannot be removed by surgery.
Randomized. Arm I (pertuzumab, trastuzumab / Perjeta, Herceptin); Arm II (cetuximab, irinotecan hydrochloride)

Ubicación	Situación
Estados Unidos
Anchorage Associates in Radiation Medicine Anchorage, Alaska 98508	Activo, no recluta
Anchorage Radiation Therapy Center Anchorage, Alaska 99504	Activo, no recluta
Alaska Breast Care and Surgery LLC Anchorage, Alaska 99508	Activo, no recluta
Alaska Oncology and Hematology LLC Anchorage, Alaska 99508	Activo, no recluta
Alaska Women's Cancer Care Anchorage, Alaska 99508	Activo, no recluta
Anchorage Oncology Centre Anchorage, Alaska 99508	Activo, no recluta
Katmai Oncology Group Anchorage, Alaska 99508	Activo, no recluta
Providence Alaska Medical Center Anchorage, Alaska 99508	Activo, no recluta
Fairbanks Memorial Hospital Fairbanks, Alaska 99701	Activo, no recluta
CTCA at Western Regional Medical Center Goodyear, Arizona 85338	Activo, no recluta
Centro Médico Regional de Kingman Kingman, Arizona 86401	Activo, no recluta
Mercy Hospital Fort Smith Fort Smith, Arkansas 72903	Activo, no recluta
CHI Saint Vincent Cancer Center Hot Springs Hot Springs, Arkansas 71913	Activo, no recluta
Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro Jonesboro, Arkansas 72401	Activo, no recluta
Kaiser Permanente-Anaheim Anaheim, California 92806	Activo, no recluta
Mission Hope Medical Oncology - Arroyo Grande Arroyo Grande, California 93420	Activo, no recluta
PCR Oncology Arroyo Grande, California 93420	Activo, no recluta
Sutter Auburn Faith Hospital Auburn, California 95602	Activo, no recluta
Sutter Cancer Centers Radiation Oncology Services-Auburn Auburn, California 95603	Activo, no recluta
Kaiser Permanente-Baldwin Park Baldwin Park, California 91706	Activo, no recluta
Kaiser Permanente-Bellflower Bellflower, California 90706	Activo, no recluta
Alta Bates Summit Medical Center-Herrick Campus Berkeley, California 94704	Activo, no recluta
Providence Saint Joseph Medical Center/Disney Family Cancer Center Burbank, California 91505	Activo, no recluta
Mills-Peninsula Medical Center Burlingame, California 94010	Activo, no recluta
Sutter Cancer Centers Radiation Oncology Services-Cameron Park Cameron Park, California 95682	Activo, no recluta
Eden Hospital Medical Center Castro Valley, California 94546	Activo, no recluta
City of Hope Corona Corona, California 92879	Activo, no recluta
UC Irvine Health Cancer Center-Newport Costa Mesa, California 92627	Activo, no recluta
Sutter Davis Hospital Davis, California 95616	Activo, no recluta
City of Hope Comprehensive Cancer Center Duarte, California 91010	Activo, no recluta
Epic Care-Dublin Dublin, California 94568	Activo, no recluta
Bay Area Breast Surgeons Inc Emeryville, California 94608	Activo, no recluta
Epic Care Partners in Cancer Care Emeryville, California 94608	Activo, no recluta
Kaiser Permanente-Fontana Fontana, California 92335	Activo, no recluta
Palo Alto Medical Foundation-Fremont Fremont, California 94538	Activo, no recluta
Kaiser Permanente - Harbor City Harbor City, California 90710	Activo, no recluta
Kaiser Permanente-Irvine Irvine, California 92618	Activo, no recluta
City of Hope Antelope Valley Lancaster, California 93534	Activo, no recluta
Centro Médico de la Universidad de Loma Linda Loma Linda, California 92354	Activo, no recluta
Kaiser Permanente Los Angeles Medical Center Los Angeles, California 90027	Activo, no recluta
Los Angeles County-USC Medical Center Los Angeles, California 90033	Activo, no recluta
USC / Norris Comprehensive Cancer Center Los Angeles, California 90033	Activo, no recluta
Kaiser Permanente West Los Angeles Los Angeles, California 90034	Activo, no recluta
Contra Costa Regional Medical Center Martinez, California 94553-3156	Activo, no recluta
Fremont - Rideout Cancer Center Marysville, California 95901	Activo, no recluta
City of Hope Mission Hills Mission Hills, California 91345	Activo, no recluta
Memorial Medical Center Modesto, California 95355	Activo, no recluta
Palo Alto Medical Foundation-Camino Division Mountain View, California 94040	Activo, no recluta
Palo Alto Medical Foundation-Gynecologic Oncology Mountain View, California 94040	Activo, no recluta
Sutter Cancer Research Consortium Novato, California 94945	Activo, no recluta
Alta Bates Summit Medical Center - Summit Campus Oakland, California 94609	Activo, no recluta
Bay Area Tumor Institute Oakland, California 94609	Activo, no recluta
Kaiser Permanente-Ontario Ontario, California 91761	Activo, no recluta
UC Irvine Health/Chao Family Comprehensive Cancer Center Orange, California 92868	Activo, no recluta
Palo Alto Medical Foundation Health Care Palo Alto, California 94301	Activo, no recluta
Kaiser Permanente - Panorama City Panorama City, California 91402	Activo, no recluta
Kaiser Permanente-Riverside Riverside, California 92505	Activo, no recluta
Sutter Cancer Centers Radiation Oncology Services-Roseville Roseville, California 95661	Activo, no recluta
Sutter Roseville Medical Center Roseville, California 95661	Activo, no recluta
Sutter Medical Center Sacramento Sacramento, California 95816	Activo, no recluta
Centro Oncológico Integral de la Universidad de California Davis Sacramento, California 95817	Activo, no recluta
Kaiser Permanente-San Diego Mission San Diego, California 92108	Activo, no recluta
Kaiser Permanente-San Diego Zion San Diego, California 92120	Activo, no recluta
California Pacific Medical Center-Pacific Campus San Francisco, California 94115	Activo, no recluta
Pacific Central Coast Health Center-San Luis Obispo San Luis Obispo, California 93401	Activo, no recluta
Kaiser Permanente-San Marcos San Marcos, California 92078	Activo, no recluta
Mills Health Center San Mateo, California 94401	Activo, no recluta
City of Hope - Santa Clarita Santa Clarita, California 91355	Activo, no recluta
Palo Alto Medical Foundation-Santa Cruz Santa Cruz, California 95065	Activo, no recluta
Mission Hope Medical Oncology - Santa Maria Santa Maria, California 93444	Activo, no recluta
Sutter Pacific Medical Foundation Santa Rosa, California 95403	Activo, no recluta
City of Hope South Pasadena South Pasadena, California 91030	Activo, no recluta
Palo Alto Medical Foundation-Sunnyvale Sunnyvale, California 94086	Activo, no recluta
City of Hope Upland Upland, California 91786	Activo, no recluta
Sutter Cancer Centers Radiation Oncology Services-Vacaville Vacaville, California 95687	Activo, no recluta
Sutter Solano Medical Center/Cancer Center Vallejo, California 94589	Activo, no recluta
Epic Care Cyberknife Center Walnut Creek, California 94597	Activo, no recluta
City of Hope West Covina West Covina, California 91790	Activo, no recluta
Kaiser Permanente-Woodland Hills Woodland Hills, California 91367	Activo, no recluta
Rocky Mountain Cancer Centers-Aurora Aurora, Colorado 80012	Activo, no recluta
The Medical Center of Aurora Aurora, Colorado 80012	Activo, no recluta
Hospital Infantil de Colorado Aurora, Colorado 80045	Activo, no recluta
Hospital de la Universidad de Colorado Aurora, Colorado 80045	Activo, no recluta
Boulder Community Hospital Boulder, Colorado 80301	Activo, no recluta
Boulder Community Foothills Hospital Boulder, Colorado 80303	Activo, no recluta
Rocky Mountain Cancer Centers-Boulder Boulder, Colorado 80304	Activo, no recluta
Rocky Mountain Cancer Centers - Centennial Centennial, Colorado 80112	Activo, no recluta
Penrose-Saint Francis Healthcare Colorado Springs, Colorado 80907	Activo, no recluta
Rocky Mountain Cancer Centers-Penrose Colorado Springs, Colorado 80907	Activo, no recluta
UCHealth Memorial Hospital Central Colorado Springs, Colorado 80909	Activo, no recluta
Memorial Hospital North Colorado Springs, Colorado 80920	Activo, no recluta
Cancer Center of Colorado at Sloan's Lake Denver, Colorado 80204	Activo, no recluta
Denver Health Medical Center Denver, Colorado 80204	Activo, no recluta
National Jewish Health-Main Campus Denver, Colorado 80206	Activo, no recluta
The Women's Imaging Center Denver, Colorado 80209	Activo, no recluta
Porter Adventist Hospital Denver, Colorado 80210	Activo, no recluta
Colorado Blood Cancer Institute Denver, Colorado 80218	Activo, no recluta
Presbyterian - Saint Lukes Medical Center - Health One Denver, Colorado 80218	Activo, no recluta
Rocky Mountain Cancer Centers-Midtown Denver, Colorado 80218	Activo, no recluta
SCL Health Saint Joseph Hospital Denver, Colorado 80218	Activo, no recluta
Rocky Mountain Cancer Centers-Rose Denver, Colorado 80220	Activo, no recluta
Rose Medical Center Denver, Colorado 80220	Activo, no recluta
Mercy Medical Center Durango, Colorado 81301	Activo, no recluta
Southwest Oncology PC Durango, Colorado 81301	Activo, no recluta
Mountain Blue Cancer Care Center - Swedish Englewood, Colorado 80113	Activo, no recluta
Rocky Mountain Cancer Centers - Swedish Englewood, Colorado 80113	Activo, no recluta
Swedish Medical Center Englewood, Colorado 80113	Activo, no recluta
The Melanoma and Skin Cancer Institute Englewood, Colorado 80113	Activo, no recluta
Poudre Valley Hospital Fort Collins, Colorado 80524	Activo, no recluta
Cancer Care and Hematology-Fort Collins Fort Collins, Colorado 80528	Activo, no recluta
Mountain Blue Cancer Care Center Golden, Colorado 80401	Activo, no recluta
National Jewish Health-Western Hematology Oncology Golden, Colorado 80401	Activo, no recluta
Saint Mary's Hospital and Regional Medical Center Grand Junction, Colorado 81501	Activo, no recluta
Grand Valley Oncology Grand Junction, Colorado 81505	Activo, no recluta
North Colorado Medical Center Greeley, Colorado 80631	Activo, no recluta
UCHealth Greeley Hospital Greeley, Colorado 80631	Activo, no recluta
UCHealth Highlands Ranch Hospital Highlands Ranch, Colorado 80129	Activo, no recluta
Good Samaritan Medical Center Lafayette, Colorado 80026	Activo, no recluta
Rocky Mountain Cancer Centers-Lakewood Lakewood, Colorado 80228	Activo, no recluta
Saint Anthony Hospital Lakewood, Colorado 80228	Activo, no recluta
Rocky Mountain Cancer Centers-Littleton Littleton, Colorado 80120	Activo, no recluta
Littleton Adventist Hospital Littleton, Colorado 80122	Activo, no recluta
Rocky Mountain Cancer Centers-Sky Ridge Lone Tree, Colorado 80124	Activo, no recluta
Sky Ridge Medical Center Lone Tree, Colorado 80124	Activo, no recluta
Longmont United Hospital Longmont, Colorado 80501	Activo, no recluta
Rocky Mountain Cancer Centers-Longmont Longmont, Colorado 80501	Activo, no recluta
Medical Center of the Rockies Loveland, Colorado 80538	Activo, no recluta
McKee Medical Center Loveland, Colorado 80539	Activo, no recluta
Parker Adventist Hospital Parker, Colorado 80138	Activo, no recluta
Rocky Mountain Cancer Centers-Parker Parker, Colorado 80138	Activo, no recluta
Saint Mary Corwin Medical Center Pueblo, Colorado 81004	Activo, no recluta
Rocky Mountain Cancer Centers - Pueblo Pueblo, Colorado 81008	Activo, no recluta
National Jewish Health-Northern Hematology Oncology Thornton, Colorado 80260	Activo, no recluta
Rocky Mountain Cancer Centers-Thornton Thornton, Colorado 80260	Activo, no recluta
SCL Health Lutheran Medical Center Wheat Ridge, Colorado 80033	Activo, no recluta
Smilow Cancer Hospital-Derby Care Center Derby, Connecticut 06418	Activo, no recluta
Smilow Cancer Hospital Care Center-Fairfield Fairfield, Connecticut 06824	Activo, no recluta
Smilow Cancer Hospital Care Center at Glastonbury Glastonbury, Connecticut 06033	Activo, no recluta
Smilow Cancer Hospital Care Center - Guiford Guilford, Connecticut 06437	Activo, no recluta
Smilow Cancer Hospital Care Center at Saint Francis Hartford, Connecticut 06105	Activo, no recluta
Middlesex Hospital Middletown, Connecticut 06457	Activo, no recluta
Centro Oncológico Smilow/Hospital de Yale-New Haven New Haven, Connecticut 06510	Activo, no recluta
Universidad de Yale New Haven, Connecticut 06520	Activo, no recluta
Yale-New Haven Hospital North Haven Medical Center North Haven, Connecticut 06473	Activo, no recluta
Smilow Cancer Hospital-Orange Care Center Orange, Connecticut 06477	Activo, no recluta
Smilow Cancer Hospital-Torrington Care Center Torrington, Connecticut 06790	Activo, no recluta
Smilow Cancer Hospital Care Center-Trumbull Trumbull, Connecticut 06611	Activo, no recluta
Smilow Cancer Hospital-Waterbury Care Center Waterbury, Connecticut 06708	Activo, no recluta
Smilow Cancer Hospital Care Center - Waterford Waterford, Connecticut 06385	Activo, no recluta
Mount Sinai Comprehensive Cancer Center at Aventura Aventura, Florida 33180	Activo, no recluta
Holy Cross Hospital Fort Lauderdale, Florida 33308	Activo, no recluta
Lee Memorial Health System Fort Myers, Florida 33901	Activo, no recluta
Regional Cancer Center-Lee Memorial Health System Fort Myers, Florida 33905	Activo, no recluta
Memorial Regional Hospital/Joe DiMaggio Children's Hospital Hollywood, Florida 33021	Activo, no recluta
Mount Sinai Medical Center Miami Beach, Florida 33140	Activo, no recluta
Memorial Hospital West Pembroke Pines, Florida 33028	Activo, no recluta
Low Country Cancer Care Savannah, Georgia 31404	Activo, no recluta
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler Savannah, Georgia 31405	Activo, no recluta
Summit Cancer Care-Candler Savannah, Georgia 31405	Activo, no recluta
Hawaii Cancer Care - Savio 'Aiea, Hawaii 96701	Activo, no recluta
Pali Momi Medical Center 'Aiea, Hawaii 96701	Activo, no recluta
Queen's Cancer Center - Pearlridge 'Aiea, Hawaii 96701	Activo, no recluta
The Cancer Center of Hawaii-Pali Momi 'Aiea, Hawaii 96701	Activo, no recluta
Hawaii Cancer Care Inc - Waterfront Plaza Honolulu, Hawai 96813	Activo, no recluta
Island Urology Honolulu, Hawai 96813	Activo, no recluta
Queen's Cancer Cenrer - POB I Honolulu, Hawai 96813	Activo, no recluta
Centro Médico Queen Honolulu, Hawai 96813	Activo, no recluta
Straub Clinic and Hospital Honolulu, Hawai 96813	Activo, no recluta
University of Hawaii Cancer Center Honolulu, Hawai 96813	Activo, no recluta
Hawaii Cancer Care Inc-Liliha Honolulu, Hawaii 96817	Activo, no recluta
Kuakini Medical Center Honolulu, Hawaii 96817	Activo, no recluta
Queen's Cancer Center - Kuakini Honolulu, Hawaii 96817	Activo, no recluta
The Cancer Center of Hawaii-Liliha Honolulu, Hawaii 96817	Activo, no recluta
Kapiolani Medical Center for Women and Children Honolulu, Hawaii 96826	Activo, no recluta
Wilcox Memorial Hospital and Kauai Medical Clinic Lihue, Hawaii 96766	Activo, no recluta
Saint Alphonsus Cancer Care Center-Boise Boise, Idaho 83706	Activo, no recluta
Instituto Oncológico Saint Luke's - Boise Boise, Idaho 83712	Activo, no recluta
Saint Alphonsus Cancer Care Center-Caldwell Caldwell, Idaho 83605	Activo, no recluta
Kootenai Health - Coeur d'Alene Coeur d'Alene, Idaho 83814	Activo, no recluta
Walter Knox Memorial Hospital Emmett, Idaho 83617	Activo, no recluta
Instituto Oncológico Saint Luke's - Fruitland Fruitland, Idaho 83619	Activo, no recluta
Idaho Urologic Institute-Meridian Meridian, Idaho 83642	Activo, no recluta
Instituto Oncológico Saint Luke's - Meridian Meridian, Idaho 83642	Activo, no recluta
Saint Alphonsus Medical Center-Nampa Nampa, Idaho 83686	Activo, no recluta
Instituto Oncológico Saint Luke's - Nampa Nampa, Idaho 83686	Activo, no recluta
Kootenai Clinic Cancer Services - Post Falls Post Falls, Idaho 83854	Activo, no recluta
Kootenai Cancer Clinic Sandpoint, Idaho 83864	Activo, no recluta
Instituto Oncológico Saint Luke's - Twin Falls Twin Falls, Idaho 83301	Activo, no recluta
Saint Anthony's Health Alton, Illinois 62002	Activo, no recluta
Rush - Copley Medical Center Aurora, Illinois 60504	Activo, no recluta
Illinois CancerCare-Bloomington Bloomington, Illinois 61704	Activo, no recluta
Loyola Center for Health at Burr Ridge Burr Ridge, Illinois 60527	Activo, no recluta
Illinois CancerCare-Canton Canton, Illinois 61520	Activo, no recluta
Memorial Hospital of Carbondale Carbondale, Illinois 62902	Activo, no recluta
SIH Cancer Institute Carterville, Illinois 62918	Activo, no recluta
Illinois CancerCare-Carthage Carthage, Illinois 62321	Activo, no recluta
Centralia Oncology Clinic Centralia, Illinois 62801	Activo, no recluta
Northwestern University Chicago, Illinois 60611	Activo, no recluta
Carle on Vermilion Danville, Illinois 61832	Activo, no recluta
Cancer Care Specialists of Illinois - Decatur Decatur, Illinois 62526	Activo, no recluta
Decatur Memorial Hospital Decatur, Illinois 62526	Activo, no recluta
Northwestern Medicine Cancer Center Kishwaukee DeKalb, Illinois 60115	Activo, no recluta
Illinois CancerCare-Dixon Dixon, Illinois 61021	Activo, no recluta
Carle Physician Group-Effingham Effingham, Illinois 62401	Activo, no recluta
Crossroads Cancer Center Effingham, Illinois 62401	Activo, no recluta
Illinois CancerCare-Eureka Eureka, Illinois 61530	Activo, no recluta
Illinois CancerCare-Galesburg Galesburg, Illinois 61401	Activo, no recluta
Western Illinois Cancer Treatment Center Galesburg, Illinois 61401	Activo, no recluta
Northwestern Medicine Cancer Center Delnor Geneva, Illinois 60134	Activo, no recluta
Loyola Medicine Homer Glen Homer Glen, Illinois 60491	Activo, no recluta
Illinois CancerCare-Kewanee Clinic Kewanee, Illinois 61443	Activo, no recluta
Northwestern Medicine Lake Forest Hospital Lake Forest, Illinois 60045	Activo, no recluta
Illinois CancerCare-Macomb Macomb, Illinois 61455	Activo, no recluta
Carle Physician Group-Mattoon/Charleston Mattoon, Illinois 61938	Activo, no recluta
Loyola University Medical Center Maywood, Illinois 60153	Activo, no recluta
Marjorie Weinberg Cancer Center at Loyola-Gottlieb Melrose Park, Illinois 60160	Activo, no recluta
Good Samaritan Regional Health Center Mount Vernon, Illinois 62864	Activo, no recluta
Cancer Care Center of O'Fallon O'Fallon, Illinois 62269	Activo, no recluta
Illinois CancerCare-Ottawa Clinic Ottawa, Illinois 61350	Activo, no recluta
Illinois CancerCare-Pekin Pekin, Illinois 61554	Activo, no recluta
OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center Pekin, Illinois 61554	Activo, no recluta
Illinois CancerCare-Peoria Peoria, Illinois 61615	Activo, no recluta
OSF Saint Francis Radiation Oncology at Peoria Cancer Center Peoria, Illinois 61615	Activo, no recluta
Methodist Medical Center of Illinois Peoria, Illinois 61636	Activo, no recluta
OSF Saint Francis Medical Center Peoria, Illinois 61637	Activo, no recluta
Illinois CancerCare-Peru Peru, Illinois 61354	Activo, no recluta
Valley Radiation Oncology Peru, Illinois 61354	Activo, no recluta
Illinois CancerCare-Princeton Princeton, Illinois 61356	Activo, no recluta
Southern Illinois University School of Medicine Springfield, Illinois 62702	Activo, no recluta
Springfield Clinic Springfield, Illinois 62702	Activo, no recluta
Memorial Medical Center Springfield, Illinois 62781	Activo, no recluta
Southwest Illinois Health Services LLP Swansea, Illinois 62226	Activo, no recluta
Carle Cancer Center Urbana, Illinois 61801	Activo, no recluta
The Carle Foundation Hospital Urbana, Illinois 61801	Activo, no recluta
Northwestern Medicine Cancer Center Warrenville Warrenville, Illinois 60555	Activo, no recluta
Illinois CancerCare - Washington Washington, Illinois 61571	Activo, no recluta
Rush-Copley Healthcare Center Yorkville, Illinois 60560	Activo, no recluta
Community Cancer Center East Indianapolis, Indiana 46219	Activo, no recluta
Community Cancer Center South Indianapolis, Indiana 46227	Activo, no recluta
Franciscan Health Indianapolis Indianapolis, Indiana 46237	Activo, no recluta
Community Cancer Center North Indianapolis, Indiana 46256	Activo, no recluta
Community Howard Regional Health Kokomo, Indiana 46904	Activo, no recluta
Franciscan Saint Elizabeth Health - Lafayette East Lafayette, Indiana 47905	Activo, no recluta
Woodland Cancer Care Center Michigan City, Indiana 46360	Activo, no recluta
Memorial Regional Cancer Center Day Road Mishawaka, Indiana 46545	Activo, no recluta
Franciscan Health Mooresville Mooresville, Indiana 46158	Activo, no recluta
Baptist Health Floyd New Albany, Indiana 47150	Activo, no recluta
Reid Health Richmond, Indiana 47374	Activo, no recluta
Memorial Hospital of South Bend South Bend, Indiana 46601	Activo, no recluta
Union Hospital Terre Haute, Indiana 47804	Activo, no recluta
Saint Anthony Regional Hospital Carroll, Iowa 51401	Activo, no recluta
Medical Oncology and Hematology Associates-West Des Moines Clive, Iowa 50325	Activo, no recluta
Centro oncológico Mercy-West Lakes Clive, Iowa 50325	Activo, no recluta
Jennie Edmundson Memorial Hospital Council Bluffs, Iowa 51502	Activo, no recluta
Alegent Health Mercy Hospital Council Bluffs, Iowa 51503	Activo, no recluta
Heartland Oncology and Hematology LLP Council Bluffs, Iowa 51503	Activo, no recluta
Gran Centro Médico Regional Creston, Iowa 50801	Activo, no recluta
Centro Médico Metodista de Iowa Des Moines, Iowa 50309	Activo, no recluta
Medical Oncology and Hematology Associates-Des Moines Des Moines, Iowa 50309	Activo, no recluta
Broadlawns Medical Center Des Moines, Iowa 50314	Activo, no recluta
Medical Oncology and Hematology Associates-Laurel Des Moines, Iowa 50314	Activo, no recluta
Centro Médico Mercy - Des Moines Des Moines, Iowa 50314	Activo, no recluta
Iowa Lutheran Hospital Des Moines, Iowa 50316	Activo, no recluta
Trinity Regional Medical Center Fort Dodge, Iowa 50501	Activo, no recluta
Methodist West Hospital West Des Moines, Iowa 50266-7700	Activo, no recluta
Centro Médico Mercy-West Lakes West Des Moines, Iowa 50266	Activo, no recluta
Coffeyville Regional Medical Center Coffeyville, Kansas 67337	Activo, no recluta
University of Kansas Clinical Research Center Fairway, Kansas 66205	Activo, no recluta
Central Care Cancer Center - Garden City Garden City, Kansas 67846	Activo, no recluta
Central Care Cancer Center - Great Bend Great Bend, Kansas 67530	Activo, no recluta
HaysMed University of Kansas Health System Hays, Kansas 67601	Activo, no recluta
University of Kansas Cancer Center-West Kansas City, Kansas 66112	Activo, no recluta
University of Kansas Cancer Center Kansas City, Kansas 66160	Activo, no recluta
Lawrence Memorial Hospital Lawrence, Kansas 66044	Activo, no recluta
Kansas Institute of Medicine Cancer and Blood Center Lenexa, Kansas 66219	Activo, no recluta
Minimally Invasive Surgery Hospital Lenexa, Kansas 66219	Activo, no recluta
Olathe Health Cancer Center Olathe, Kansas 66061	Activo, no recluta
Menorah Medical Center Overland Park, Kansas 66209	Activo, no recluta
University of Kansas Cancer Center-Overland Park Overland Park, Kansas 66210	Activo, no recluta
Ascension Via Christi - Pittsburg Pittsburg, Kansas 66762	Activo, no recluta
Salina Regional Health Center Salina, Kansas 67401	Activo, no recluta
University of Kansas Health System Saint Francis Campus Topeka, Kansas 66606	Activo, no recluta
University of Kansas Hospital-Westwood Cancer Center Westwood, Kansas 66205	Activo, no recluta
Cancer Center of Kansas-Wichita Medical Arts Tower Wichita, Kansas 67208	Activo, no recluta
Cancer Center of Kansas - Wichita Wichita, Kansas 67214	Activo, no recluta
Flaget Memorial Hospital Bardstown, Kentucky 40004	Activo, no recluta
Baptist Health Corbin Corbin, Kentucky 40701	Activo, no recluta
Commonwealth Cancer Center-Corbin Corbin, Kentucky 40701	Activo, no recluta
Baptist Health Lexington Lexington, Kentucky 40503	Activo, no recluta
Saint Joseph Radiation Oncology Resource Center Lexington, Kentucky 40504	Activo, no recluta
Saint Joseph Hospital East Lexington, Kentucky 40509	Activo, no recluta
Universidad de Kentucky/Centro Oncológico Markey Lexington, Kentucky 40536	Activo, no recluta
Saint Joseph London London, Kentucky 40741	Activo, no recluta
Jewish Hospital Louisville, Kentucky 40202	Activo, no recluta
Baptist Health Louisville Louisville, Kentucky 40207	Activo, no recluta
Saints Mary and Elizabeth Hospital Louisville, Kentucky 40215	Activo, no recluta
Jewish Hospital Medical Center Northeast Louisville, Kentucky 40245	Activo, no recluta
Baptist Health Madisonville/Merle Mahr Cancer Center Madisonville, Kentucky 42431	Activo, no recluta
Baptist Health Paducah Paducah, Kentucky 42003	Activo, no recluta
Jewish Hospital Medical Center South Shepherdsville, Kentucky 40165	Activo, no recluta
Ochsner Health Center-Summa Baton Rouge, Louisiana 70809	Activo, no recluta
Medical Center of Baton Rouge Baton Rouge, Louisiana 70816	Activo, no recluta
Ochsner High Grove Baton Rouge, Louisiana 70836	Activo, no recluta
Ochsner Medical Center Jefferson New Orleans, Louisiana 70121	Activo, no recluta
University of Maryland/Greenebaum Cancer Center Baltimore, Maryland 21201	Activo, no recluta
Beverly Hospital Beverly, Massachusetts 01915	Activo, no recluta
Lahey Hospital and Medical Center Burlington, Massachusetts 01805	Activo, no recluta
Addison Gilbert Hospital Gloucester, Massachusetts 01930	Activo, no recluta
Lahey Medical Center-Peabody Peabody, Massachusetts 01960	Activo, no recluta
Mercy Medical Center Springfield, Massachusetts 01104	Activo, no recluta
Winchester Hospital Winchester, Massachusetts 01890	Activo, no recluta
Hickman Cancer Center Adrian, Michigan 49221	Activo, no recluta
Saint Joseph Mercy Hospital Ann Arbor, Michigan 48106	Activo, no recluta
University of Michigan Comprehensive Cancer Center Ann Arbor, Michigan 48109	Activo, no recluta
Bronson Battle Creek Battle Creek, Michigan 49017	Activo, no recluta
McLaren Cancer Institute-Bay City Bay City, Michigan 48706	Activo, no recluta
McLaren Cancer Institute-Bloomfield Bloomfield, Michigan 48302	Activo, no recluta
IHA Hematology Oncology Consultants-Brighton Brighton, Michigan 48114	Activo, no recluta
Saint Joseph Mercy Brighton Brighton, Michigan 48114	Activo, no recluta
Henry Ford Cancer Institute-Downriver Brownstown, Michigan 48183	Activo, no recluta
IHA Hematology Oncology Consultants-Canton Canton, Michigan 48188	Activo, no recluta
Saint Joseph Mercy Canton Canton, Michigan 48188	Activo, no recluta
Caro Cancer Center Caro, Michigan 48723	Activo, no recluta
IHA Hematology Oncology Consultants-Chelsea Chelsea, Michigan 48118	Activo, no recluta
Saint Joseph Mercy Chelsea Chelsea, Michigan 48118	Activo, no recluta
Hematology Oncology Consultants-Clarkston Clarkston, Michigan 48346	Activo, no recluta
McLaren Cancer Institute-Clarkston Clarkston, Michigan 48346	Activo, no recluta
Newland Medical Associates-Clarkston Clarkston, Michigan 48346	Activo, no recluta
Henry Ford Macomb Hospital-Clinton Township Clinton Township, Michigan 48038	Activo, no recluta
Beaumont Hospital - Dearborn Dearborn, Michigan 48124	Activo, no recluta
Henry Ford Medical Center-Fairlane Dearborn, Michigan 48126	Activo, no recluta
Wayne State University/Karmanos Cancer Institute Detroit, Michigan 48201	Activo, no recluta
Hospital Henry Ford Detroit, Michigan 48202	Activo, no recluta
Ascension Saint John Hospital Detroit, Michigan 48236	Activo, no recluta
Great Lakes Cancer Management Specialists-Doctors Park East China Township, Michigan 48054	Activo, no recluta
Weisberg Cancer Treatment Center Farmington Hills, Michigan 48334	Activo, no recluta
Genesee Cancer and Blood Disease Treatment Center Flint, Michigan 48503	Activo, no recluta
Genesee Hematology Oncology PC Flint, Michigan 48503	Activo, no recluta
Instituto Oncológico Genesys Hurley Flint, Michigan 48503	Activo, no recluta
Centro Médico Hurley Flint, Michigan 48503	Activo, no recluta
Singh and Arora Hematology Oncology PC Flint, Michigan 48532	Activo, no recluta
Helen DeVos Children's Hospital at Spectrum Health Grand Rapids, Michigan 49503	Activo, no recluta
Mercy Health Saint Mary's Grand Rapids, Michigan 49503	Activo, no recluta
Spectrum Health at Butterworth Campus Grand Rapids, Michigan 49503	Activo, no recluta
Academic Hematology Oncology Specialists Grosse Pointe Woods, Michigan 48236	Activo, no recluta
Great Lakes Cancer Management Specialists-Van Elslander Cancer Center Grosse Pointe Woods, Michigan 48236	Activo, no recluta
Michigan Breast Specialists-Grosse Pointe Woods Grosse Pointe Woods, Michigan 48236	Activo, no recluta
Allegiance Health Jackson, Michigan 49201	Activo, no recluta
Bronson Methodist Hospital Kalamazoo, Michigan 49007	Activo, no recluta
West Michigan Cancer Center Kalamazoo, Michigan 49007	Activo, no recluta
Borgess Medical Center Kalamazoo, Michigan 49048	Activo, no recluta
McLaren-Greater Lansing Lansing, Michigan 48910	Activo, no recluta
Mid-Michigan Physicians-Lansing Lansing, Michigan 48912	Activo, no recluta
Sparrow Hospital Lansing, Michigan 48912	Activo, no recluta
Hope Cancer Clinic Livonia, Michigan 48154	Activo, no recluta
Saint Mary Mercy Hospital Livonia, Michigan 48154	Activo, no recluta
Great Lakes Cancer Management Specialists-Macomb Medical Campus Macomb, Michigan 48044	Activo, no recluta
Michigan Breast Specialists-Macomb Township Macomb, Michigan 48044	Activo, no recluta
Saint Mary's Oncology/Hematology Associates of Marlette Marlette, Michigan 48453	Activo, no recluta
Toledo Clinic Cancer Centers-Monroe Monroe, Michigan 48162	Activo, no recluta
McLaren Cancer Institute-Macomb Mount Clemens, Michigan 48043	Activo, no recluta
McLaren Cancer Institute-Central Michigan Mount Pleasant, Michigan 48858	Activo, no recluta
Mercy Health Mercy Campus Muskegon, Michigan 49444	Activo, no recluta
Lakeland Hospital Niles Niles, Michigan 49120	Activo, no recluta
Cancer and Hematology Centers of Western Michigan - Norton Shores Norton Shores, Michigan 49444	Activo, no recluta
Henry Ford Medical Center-Columbus Novi, Michigan 48377	Activo, no recluta
McLaren Cancer Institute-Northern Michigan Petoskey, Michigan 49770	Activo, no recluta
21st Century Oncology-Pontiac Pontiac, Michigan 48341	Activo, no recluta
Hope Cancer Center Pontiac, Michigan 48341	Activo, no recluta
Newland Medical Associates-Pontiac Pontiac, Michigan 48341	Activo, no recluta
Saint Joseph Mercy Oakland Pontiac, Michigan 48341	Activo, no recluta
Huron Medical Center PC Port Huron, Michigan 48060	Activo, no recluta
Lake Huron Medical Center Port Huron, Michigan 48060	Activo, no recluta
McLaren-Port Huron Port Huron, Michigan 48060	Activo, no recluta
Spectrum Health Reed City Hospital Reed City, Michigan 49677	Activo, no recluta
Great Lakes Cancer Management Specialists-Rochester Hills Rochester Hills, Michigan 48309	Activo, no recluta
Ascension Saint Mary's Hospital Saginaw, Michigan 48601	Activo, no recluta
Oncology Hematology Associates of Saginaw Valley PC Saginaw, Michigan 48604	Activo, no recluta
Lakeland Medical Center Saint Joseph Saint Joseph, Michigan 49085	Activo, no recluta
Marie Yeager Cancer Center Saint Joseph, Michigan 49085	Activo, no recluta
Henry Ford Macomb Health Center - Shelby Township Shelby, Michigan 48315	Activo, no recluta
Bhadresh Nayak MD PC-Sterling Heights Sterling Heights, Michigan 48312	Activo, no recluta
Ascension Saint Joseph Hospital Tawas City, Michigan 48764	Activo, no recluta
Munson Medical Center Traverse City, Michigan 49684	Activo, no recluta
Advanced Breast Care Center PLLC Warren, Michigan 48088	Activo, no recluta
Great Lakes Cancer Management Specialists-Macomb Professional Building Warren, Michigan 48093	Activo, no recluta
Macomb Hematology Oncology PC Warren, Michigan 48093	Activo, no recluta
Michigan Breast Specialists-Warren Warren, Michigan 48093	Activo, no recluta
Saint John Macomb-Oakland Hospital Warren, Michigan 48093	Activo, no recluta
Henry Ford West Bloomfield Hospital West Bloomfield, Michigan 48322	Activo, no recluta
Saint Mary's Oncology/Hematology Associates of West Branch West Branch, Michigan 48661	Activo, no recluta
Metro Health Hospital Wyoming, Michigan 49519	Activo, no recluta
Huron Gastroenterology PC Ypsilanti, Michigan 48106	Activo, no recluta
IHA Hematology Oncology Consultants-Ann Arbor Ypsilanti, Michigan 48197	Activo, no recluta
Riverwood Healthcare Center Aitkin, Minnesota 56431	Activo, no recluta
Essentia Health Saint Joseph's Medical Center Brainerd, Minnesota 56401	Activo, no recluta
Fairview Ridges Hospital Burnsville, Minnesota 55337	Activo, no recluta
Minnesota Oncology - Burnsville Burnsville, Minnesota 55337	Activo, no recluta
Cambridge Medical Center Cambridge, Minnesota 55008	Activo, no recluta
Mercy Hospital Coon Rapids, Minnesota 55433	Activo, no recluta
Essentia Health - Deer River Clinic Deer River, Minnesota 56636	Activo, no recluta
Essentia Health Saint Mary's - Detroit Lakes Clinic Detroit Lakes, Minnesota 56501	Activo, no recluta
Essentia Health Cancer Center Duluth, Minnesota 55805	Activo, no recluta
Essentia Health Saint Mary's Medical Center Duluth, Minnesota 55805	Activo, no recluta
Miller-Dwan Hospital Duluth, Minnesota 55805	Activo, no recluta
Fairview Southdale Hospital Edina, Minnesota 55435	Activo, no recluta
Lake Region Healthcare Corporation-Cancer Care Fergus Falls, Minnesota 56537	Activo, no recluta
Essentia Health - Fosston Fosston, Minnesota 56542	Activo, no recluta
Unity Hospital Fridley, Minnesota 55432	Activo, no recluta
Essentia Health Hibbing Clinic Hibbing, Minnesota 55746	Activo, no recluta
Fairview Clinics and Surgery Center Maple Grove Maple Grove, Minnesota 55369	Activo, no recluta
Minnesota Oncology Hematology PA-Maplewood Maplewood, Minnesota 55109	Activo, no recluta
Saint John's Hospital - Healtheast Maplewood, Minnesota 55109	Activo, no recluta
Abbott-Northwestern Hospital Minneapolis, Minnesota 55407	Activo, no recluta
Hennepin County Medical Center Minneapolis, Minnesota 55415	Activo, no recluta
Health Partners Inc Minneapolis, Minnesota 55454	Activo, no recluta
Monticello Cancer Center Monticello, Minnesota 55362	Activo, no recluta
New Ulm Medical Center New Ulm, Minnesota 56073	Activo, no recluta
Essentia Health - Park Rapids Park Rapids, Minnesota 56470	Activo, no recluta
Fairview Northland Medical Center Princeton, Minnesota 55371	Activo, no recluta
North Memorial Medical Health Center Robbinsdale, Minnesota 55422	Activo, no recluta
Coborn Cancer Center at Saint Cloud Hospital Saint Cloud, Minnesota 56303	Activo, no recluta
Park Nicollet Clinic - Saint Louis Park Saint Louis Park, Minnesota 55416	Activo, no recluta
Regions Hospital Saint Paul, Minnesota 55101	Activo, no recluta
United Hospital Saint Paul, Minnesota 55102	Activo, no recluta
Essentia Health Sandstone Sandstone, Minnesota 55072	Activo, no recluta
Saint Francis Regional Medical Center Shakopee, Minnesota 55379	Activo, no recluta
Lakeview Hospital Stillwater, Minnesota 55082	Activo, no recluta
Essentia Health Virginia Clinic Virginia, Minnesota 55792	Activo, no recluta
Ridgeview Medical Center Waconia, Minnesota 55387	Activo, no recluta
Rice Memorial Hospital Willmar, Minnesota 56201	Activo, no recluta
Minnesota Oncology Hematology PA-Woodbury Woodbury, Minnesota 55125	Activo, no recluta
Fairview Lakes Medical Center Wyoming, Minnesota 55092	Activo, no recluta
Singing River Hospital Pascagoula, Mississippi 39581	Activo, no recluta
Saint Louis Cancer and Breast Institute-Ballwin Ballwin, Missouri 63011	Activo, no recluta
Central Care Cancer Center - Bolivar Bolivar, Missouri 65613	Activo, no recluta
Parkland Health Center-Bonne Terre Bonne Terre, Missouri 63628	Activo, no recluta
Cox Cancer Center Branson Branson, Missouri 65616	Activo, no recluta
Saint Francis Medical Center Cape Girardeau, Missouri 63703	Activo, no recluta
Southeast Cancer Center Cape Girardeau, Missouri 63703	Activo, no recluta
Centro Oncológico Siteman del West County Hospital Creve Coeur, Missouri 63141	Activo, no recluta
Parkland Health Center - Farmington Farmington, Missouri 63640	Activo, no recluta
Centerpoint Medical Center LLC Independence, Missouri 64057	Activo, no recluta
Capital Region Southwest Campus Jefferson City, Missouri 65109	Activo, no recluta
Freeman Health System Joplin, Missouri 64804	Activo, no recluta
Mercy Hospital Joplin Joplin, Missouri 64804	Activo, no recluta
Truman Medical Centers Kansas City, Missouri 64108	Activo, no recluta
Kansas City Veterans Affairs Medical Center Kansas City, Missouri 64128	Activo, no recluta
Research Medical Center Kansas City, Missouri 64132	Activo, no recluta
University of Kansas Cancer Center - North Kansas City, Missouri 64154	Activo, no recluta
University of Kansas Cancer Center - Lee's Summit Lee's Summit, Missouri 64064	Activo, no recluta
Delbert Day Cancer Institute at PCRMC Rolla, Missouri 65401	Activo, no recluta
Mercy Clinic-Rolla-Cancer and Hematology Rolla, Missouri 65401	Activo, no recluta
Heartland Regional Medical Center Saint Joseph, Missouri 64506	Activo, no recluta
Saint Louis Cancer and Breast Institute-South City Saint Louis, Missouri 63109	Activo, no recluta
Facultad de Medicina de la Universidad de Washington San Luis, Missouri 63110	Activo, no recluta
Mercy Hospital South Saint Louis, Missouri 63128	Activo, no recluta
Centro Oncológico Siteman-Condado Sur San Luis, Misuri 63129	Activo, no recluta
Missouri Baptist Medical Center Saint Louis, Missouri 63131	Activo, no recluta
Centro Oncológico Siteman del Christian Hospital San Luis, Misuri 63136	Activo, no recluta
Hospital Mercy de Saint Louis San Luis, Misuri 63141	Activo, no recluta
Centro Oncológico Siteman del Hospital Saint Peters San Peters, Missouri 63376	Activo, no recluta
Sainte Genevieve County Memorial Hospital Sainte Genevieve, Missouri 63670	Activo, no recluta
Hospital Mercy de Springfield Springfield, Missouri 65804	Activo, no recluta
CoxHealth South Hospital Springfield, Missouri 65807	Activo, no recluta
Missouri Baptist Sullivan Hospital Sullivan, Missouri 63080	Activo, no recluta
Missouri Baptist Outpatient Center-Sunset Hills Sunset Hills, Missouri 63127	Activo, no recluta
Mercy Hospital Washington Washington, Missouri 63090	Activo, no recluta
Community Hospital of Anaconda Anaconda, Montana 59711	Activo, no recluta
Centro Oncológico de la Clínica Billings Billings, Montana 59101	Activo, no recluta
Saint Vincent Healthcare Billings, Montana 59101	Activo, no recluta
Saint Vincent Frontier Cancer Center Billings, Montana 59102	Activo, no recluta
Bozeman Deaconess Hospital Bozeman, Montana 59715	Activo, no recluta
Saint James Community Hospital and Cancer Treatment Center Butte, Montana 59701	Activo, no recluta
Benefis Healthcare- Sletten Cancer Institute Great Falls, Montana 59405	Activo, no recluta
Great Falls Clinic Great Falls, Montana 59405	Activo, no recluta
Saint Peter's Community Hospital Helena, Montana 59601	Activo, no recluta
Kalispell Regional Medical Center Kalispell, Montana 59901	Activo, no recluta
Saint Patrick Hospital - Community Hospital Missoula, Montana 59802	Activo, no recluta
Community Medical Hospital Missoula, Montana 59804	Activo, no recluta
CHI Health Saint Francis Grand Island, Nebraska 68803	Activo, no recluta
Heartland Hematology and Oncology Kearney, Nebraska 68845	Activo, no recluta
CHI Health Good Samaritan Kearney, Nebraska 68847	Activo, no recluta
Saint Elizabeth Regional Medical Center Lincoln, Nebraska 68510	Activo, no recluta
Hospital Metodista de Nebraska Omaha, Nebraska 68114	Activo, no recluta
Alegent Health Immanuel Medical Center Omaha, Nebraska 68122	Activo, no recluta
Hematology and Oncology Consultants PC Omaha, Nebraska 68122	Activo, no recluta
Alegent Health Bergan Mercy Medical Center Omaha, Nebraska 68124	Activo, no recluta
Alegent Health Lakeside Hospital Omaha, Nebraska 68130	Activo, no recluta
Creighton University Medical Center Omaha, Nebraska 68131	Activo, no recluta
Midlands Community Hospital Papillion, Nebraska 68046	Activo, no recluta
Carson Tahoe Regional Medical Center Carson City, Nevada 89703	Activo, no recluta
Cancer and Blood Specialists-Henderson Henderson, Nevada 89052	Activo, no recluta
Comprehensive Cancer Centers of Nevada - Henderson Henderson, Nevada 89052	Activo, no recluta
Comprehensive Cancer Centers of Nevada-Horizon Ridge Henderson, Nevada 89052	Activo, no recluta
Las Vegas Cancer Center-Henderson Henderson, Nevada 89052	Activo, no recluta
OptumCare Cancer Care at Seven Hills Henderson, Nevada 89052	Activo, no recluta
21st Century Oncology-Henderson Henderson, Nevada 89074	Activo, no recluta
Comprehensive Cancer Centers of Nevada-Southeast Henderson Henderson, Nevada 89074	Activo, no recluta
Las Vegas Urology - Green Valley Henderson, Nevada 89074	Activo, no recluta
Las Vegas Urology - Pebble Henderson, Nevada 89074	Activo, no recluta
Urology Specialists of Nevada - Green Valley Henderson, Nevada 89074	Activo, no recluta
Las Vegas Urology - Pecos Las Vegas, Nevada 89074	Activo, no recluta
Desert West Surgery Las Vegas, Nevada 89102	Activo, no recluta
OptumCare Cancer Care at Charleston Las Vegas, Nevada 89102	Activo, no recluta
University Medical Center of Southern Nevada Las Vegas, Nevada 89102	Activo, no recluta
Hope Cancer Care of Nevada Las Vegas, Nevada 89103	Activo, no recluta
Cancer and Blood Specialists-Shadow Las Vegas, Nevada 89106	Activo, no recluta
Radiation Oncology Centers of Nevada Central Las Vegas, Nevada 89106	Activo, no recluta
Urology Specialists of Nevada - Central Las Vegas, Nevada 89106	Activo, no recluta
21st Century Oncology Las Vegas, Nevada 89109	Activo, no recluta
HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway Las Vegas, Nevada 89109	Activo, no recluta
Sunrise Hospital and Medical Center Las Vegas, Nevada 89109	Activo, no recluta
HealthCare Partners Medical Group Oncology/Hematology-San Martin Las Vegas, Nevada 89113	Activo, no recluta
Las Vegas Prostate Cancer Center Las Vegas, Nevada 89113	Activo, no recluta
Las Vegas Urology - Sunset Las Vegas, Nevada 89113	Activo, no recluta
Radiation Oncology Centers of Nevada Southeast Las Vegas, Nevada 89119	Activo, no recluta
Cancer Therapy and Integrative Medicine Las Vegas, Nevada 89121	Activo, no recluta
21st Century Oncology-Vegas Tenaya Las Vegas, Nevada 89128	Activo, no recluta
Ann M Wierman MD LTD Las Vegas, Nevada 89128	Activo, no recluta
Cancer and Blood Specialists-Tenaya Las Vegas, Nevada 89128	Activo, no recluta
Comprehensive Cancer Centers of Nevada - Northwest Las Vegas, Nevada 89128	Activo, no recluta
HealthCare Partners Medical Group Oncology/Hematology-Tenaya Las Vegas, Nevada 89128	Activo, no recluta
Las Vegas Urology - Cathedral Rock Las Vegas, Nevada 89128	Activo, no recluta
Las Vegas Urology - Smoke Ranch Las Vegas, Nevada 89128	Activo, no recluta
OptumCare Cancer Care at MountainView Las Vegas, Nevada 89128	Activo, no recluta
Urology Specialists of Nevada - Northwest Las Vegas, Nevada 89128	Activo, no recluta
Alliance for Childhood Diseases/Cure 4 the Kids Foundation Las Vegas, Nevada 89135	Activo, no recluta
Comprehensive Cancer Centers of Nevada - Town Center Las Vegas, Nevada 89144	Activo, no recluta
Comprehensive Cancer Centers of Nevada-Summerlin Las Vegas, Nevada 89144	Activo, no recluta
Summerlin Hospital Medical Center Las Vegas, Nevada 89144	Activo, no recluta
Las Vegas Cancer Center-Medical Center Las Vegas, Nevada 89148-2405	Activo, no recluta
21st Century Oncology-Fort Apache Las Vegas, Nevada 89148	Activo, no recluta
Centros Oncológicos Integrales de Nevada Las Vegas, Nevada 89148	Activo, no recluta
OptumCare Cancer Care at Fort Apache Las Vegas, Nevada 89148	Activo, no recluta
Urology Specialists of Nevada - Southwest Las Vegas, Nevada 89148	Activo, no recluta
HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills Las Vegas, Nevada 89149	Activo, no recluta
Comprehensive Cancer Centers of Nevada - Central Valley Las Vegas, Nevada 89169	Activo, no recluta
University Cancer Center Las Vegas, Nevada 89169	Activo, no recluta
Hope Cancer Care of Nevada-Pahrump Pahrump, Nevada 89048	Activo, no recluta
Centro Médico Regional Renown Reno, Nevada 89502	Activo, no recluta
Saint Mary's Regional Medical Center Reno, Nevada 89503	Activo, no recluta
Radiation Oncology Associates Reno, Nevada 89509	Activo, no recluta
Centro Médico Dartmouth Hitchcock Lebanon, Nuevo Hampshire 03756	Activo, no recluta
Norris Cotton Cancer Center-Manchester Manchester, New Hampshire 03102	Activo, no recluta
Norris Cotton Cancer Center-Nashua Nashua, New Hampshire 03063	Activo, no recluta
AtlantiCare Health Park-Cape May Court House Cape May Court House, New Jersey 08210	Activo, no recluta
AtlantiCare Surgery Center Egg Harbor Township, New Jersey 08234	Activo, no recluta
Inspira Medical Center Mullica Hill Mullica Hill, New Jersey 08062	Activo, no recluta
Instituto del Cáncer Rutgers de Nueva Jersey New Brunswick, Nueva Jersey 08903	Activo, no recluta
Newark Beth Israel Medical Center Newark, New Jersey 07112	Activo, no recluta
Inspira Medical Center Vineland Vineland, New Jersey 08360	Activo, no recluta
Lovelace Medical Center-Saint Joseph Square Albuquerque, New Mexico 87102	Activo, no recluta
Centro Oncológico de la Universidad de Nuevo México Albuquerque, New Mexico 87102	Activo, no recluta
New Mexico Cancer Care Alliance Albuquerque, Nuevo México 87106	Activo, no recluta
New Mexico Oncology Hematology Consultants Albuquerque, New Mexico 87109	Activo, no recluta
Presbyterian Kaseman Hospital Albuquerque, New Mexico 87110	Activo, no recluta
Memorial Medical Center - Las Cruces Las Cruces, New Mexico 88011	Activo, no recluta
Presbyterian Rust Medical Center/Jorgensen Cancer Center Rio Rancho, New Mexico 87124	Activo, no recluta
Atrium Health Stanly/LCI-Albemarle Albemarle, North Carolina 28002	Activo, no recluta
AdventHealth Infusion Center Asheville Asheville, North Carolina 28803	Activo, no recluta
Carolinas Medical Center/Levine Cancer Institute Charlotte, North Carolina 28203	Activo, no recluta
Atrium Health Pineville/LCI-Pineville Charlotte, North Carolina 28210	Activo, no recluta
Levine Cancer Institute-SouthPark Charlotte, North Carolina 28211	Activo, no recluta
Atrium Health University City/LCI-University Charlotte, North Carolina 28262	Activo, no recluta
Levine Cancer Institute-Ballantyne Charlotte, North Carolina 28277	Activo, no recluta
Southeastern Medical Oncology Center-Clinton Clinton, North Carolina 28328	Activo, no recluta
AdventHealth Infusion Center Haywood Clyde, North Carolina 28721	Activo, no recluta
Atrium Health Cabarrus/LCI-Concord Concord, North Carolina 28025	Activo, no recluta
Levine Cancer Institute - Rutherford Forest City, North Carolina 28043	Activo, no recluta
CaroMont Regional Medical Center Gastonia, North Carolina 28054	Activo, no recluta
Levine Cancer Institute-Gaston Gastonia, North Carolina 28054	Activo, no recluta
Southeastern Medical Oncology Center-Goldsboro Goldsboro, North Carolina 27534	Activo, no recluta
Wayne Memorial Hospital Goldsboro, North Carolina 27534	Activo, no recluta
AdventHealth Hendersonville Hendersonville, North Carolina 28792	Activo, no recluta
Onslow Memorial Hospital Jacksonville, North Carolina 28546	Activo, no recluta
Southeastern Medical Oncology Center-Jacksonville Jacksonville, North Carolina 28546	Activo, no recluta
Vidant Oncology-Kenansville Kenansville, North Carolina 28349	Activo, no recluta
Vidant Oncology-Kinston Kinston, North Carolina 28501	Activo, no recluta
Atrium Health Lincoln/LCI-Lincolnton Lincolnton, North Carolina 28092	Activo, no recluta
Atrium Health Union/LCI-Union Monroe, North Carolina 28112	Activo, no recluta
Vidant Oncology-Richlands Richlands, North Carolina 28574	Activo, no recluta
Atrium Health Cleveland/LCI-Cleveland Shelby, North Carolina 28150	Activo, no recluta
Johnston Memorial Hospital Smithfield, North Carolina 27577	Activo, no recluta
AdventHealth Infusion Center Weaverville Weaverville, North Carolina 28787	Activo, no recluta
Essentia Health Cancer Center-South University Clinic Fargo, North Dakota 58103	Activo, no recluta
Altru Cancer Center Grand Forks, North Dakota 58201	Activo, no recluta
Essentia Health - Jamestown Clinic Jamestown, North Dakota 58401	Activo, no recluta
Cleveland Clinic Akron General Akron, Ohio 44307	Activo, no recluta
Indu and Raj Soin Medical Center Beavercreek, Ohio 45431	Activo, no recluta
Strecker Cancer Center-Belpre Belpre, Ohio 45714	Activo, no recluta
Saint Elizabeth Boardman Hospital Boardman, Ohio 44512	Activo, no recluta
Dayton Physicians LLC-Miami Valley Sur Centerville, Ohio 45459	Activo, no recluta
Miami Valley Hospital Sur Centerville, Ohio 45459	Activo, no recluta
Adena Regional Medical Center Chillicothe, Ohio 45601	Activo, no recluta
Good Samaritan Hospital - Cincinnati Cincinnati, Ohio 45220	Activo, no recluta
Oncology Hematology Care Inc-Kenwood Cincinnati, Ohio 45236	Activo, no recluta
Bethesda North Hospital Cincinnati, Ohio 45242	Activo, no recluta
TriHealth Cancer Institute-Westside Cincinnati, Ohio 45247	Activo, no recluta
TriHealth Cancer Institute-Anderson Cincinnati, Ohio 45255	Activo, no recluta
Centro Oncológico Integral de la Universidad Estatal de Ohio Columbus, Ohio 43210	Activo, no recluta
Mount Carmel East Hospital Columbus, Ohio 43213	Activo, no recluta
Columbus Oncology and Hematology Associates Inc Columbus, Ohio 43214	Activo, no recluta
Riverside Methodist Hospital Columbus, Ohio 43214	Activo, no recluta
Grant Medical Center Columbus, Ohio 43215	Activo, no recluta
The Mark H Zangmeister Center Columbus, Ohio 43219	Activo, no recluta
Mount Carmel Health Center West Columbus, Ohio 43222	Activo, no recluta
Doctors Hospital Columbus, Ohio 43228	Activo, no recluta
Good Samaritan Hospital - Dayton Dayton, Ohio 45406	Activo, no recluta
Hospital Miami Valley Dayton, Ohio 45409	Activo, no recluta
Dayton Physician LLC-Miami Valley Hospital North Dayton, Ohio 45415	Activo, no recluta
Miami Valley Hospital Norte Dayton, Ohio 45415	Activo, no recluta
Delaware Health Center-Grady Cancer Center Delaware, Ohio 43015	Activo, no recluta
Delaware Radiation Oncology Delaware, Ohio 43015	Activo, no recluta
Grady Memorial Hospital Delaware, Ohio 43015	Activo, no recluta
Dublin Methodist Hospital Dublin, Ohio 43016	Activo, no recluta
Armes Family Cancer Center Findlay, Ohio 45840	Activo, no recluta
Blanchard Valley Hospital Findlay, Ohio 45840	Activo, no recluta
Orion Cancer Care Findlay, Ohio 45840	Activo, no recluta
Centro Médico Atrium-Hospital Regional Middletown Franklin, Ohio 45005-1066	Activo, no recluta
Dayton Physicians LLC-Atrium Franklin, Ohio 45005	Activo, no recluta
Dayton Physicians LLC-Wayne Greenville, Ohio 45331	Activo, no recluta
Wayne Hospital Greenville, Ohio 45331	Activo, no recluta
Mount Carmel Grove City Hospital Grove City, Ohio 43123	Activo, no recluta
Greater Dayton Cancer Center Kettering, Ohio 45409	Activo, no recluta
First Dayton Cancer Care Kettering, Ohio 45420	Activo, no recluta
Kettering Medical Center Kettering, Ohio 45429	Activo, no recluta
Fairfield Medical Center Lancaster, Ohio 43130	Activo, no recluta
Saint Rita's Medical Center Lima, Ohio 45801	Activo, no recluta
Hospital OhioHealth Mansfield Mansfield, Ohio 44903	Activo, no recluta
Marietta Memorial Hospital Marietta, Ohio 45750	Activo, no recluta
OhioHealth Marion General Hospital Marion, Ohio 43302	Activo, no recluta
Toledo Clinic Cancer Centers-Maumee Maumee, Ohio 43537	Activo, no recluta
Toledo Radiation Oncology at Northwest Ohio Onocolgy Center Maumee, Ohio 43537	Activo, no recluta
Knox Community Hospital Mount Vernon, Ohio 43050	Activo, no recluta
Licking Memorial Hospital Newark, Ohio 43055	Activo, no recluta
Newark Radiation Oncology Newark, Ohio 43055	Activo, no recluta
Mercy Health Perrysburg Cancer Center Perrysburg, Ohio 43551	Activo, no recluta
Southern Ohio Medical Center Portsmouth, Ohio 45662	Activo, no recluta
Springfield Regional Cancer Center Springfield, Ohio 45504	Activo, no recluta
Springfield Regional Medical Center Springfield, Ohio 45505	Activo, no recluta
Saint Vincent Mercy Medical Center Toledo, Ohio 43608	Activo, no recluta
Mercy Health - Saint Anne Hospital Toledo, Ohio 43623	Activo, no recluta
Toledo Clinic Cancer Centers-Toledo Toledo, Ohio 43623	Activo, no recluta
Dayton Physicians LLC-Upper Valley Troy, Ohio 45373	Activo, no recluta
Centro Médico Upper Valley Troy, Ohio 45373	Activo, no recluta
Saint Joseph Warren Hospital Warren, Ohio 44484	Activo, no recluta
Saint Ann's Hospital Westerville, Ohio 43081	Activo, no recluta
Saint Elizabeth Youngstown Hospital Youngstown, Ohio 44501	Activo, no recluta
Genesis Healthcare System Cancer Care Center Zanesville, Ohio 43701	Activo, no recluta
Cancer Centers of Southwest Oklahoma Research Lawton, Oklahoma 73505	Activo, no recluta
Centro de Ciencias de la Salud de la Universidad de Oklahoma Oklahoma City, Oklahoma 73104	Activo, no recluta
Integris Southwest Medical Center Oklahoma City, Oklahoma 73109	Activo, no recluta
Mercy Hospital Oklahoma City Oklahoma City, Oklahoma 73120	Activo, no recluta
Integris Cancer Institute of Oklahoma Oklahoma City, Oklahoma 73142	Activo, no recluta
Oklahoma Cancer Specialists and Research Institute-Tulsa Tulsa, Oklahoma 74146	Activo, no recluta
Saint Alphonsus Medical Center-Baker City Baker City, Oregon 97814	Activo, no recluta
Saint Charles Health System Bend, Oregon 97701	Activo, no recluta
Clackamas Radiation Oncology Center Clackamas, Oregon 97015	Activo, no recluta
Providence Cancer Institute Clackamas Clinic Clackamas, Oregon 97015	Activo, no recluta
Bay Area Hospital Coos Bay, Oregon 97420	Activo, no recluta
Providence Newberg Medical Center Newberg, Oregon 97132	Activo, no recluta
Saint Alphonsus Medical Center-Ontario Ontario, Oregon 97914	Activo, no recluta
Centro Médico Providence Portland Portland, Oregón 97213	Activo, no recluta
Providence Saint Vincent Medical Center Portland, Oregon 97225	Activo, no recluta
Saint Charles Health System-Redmond Redmond, Oregon 97756	Activo, no recluta
Lehigh Valley Hospital-Cedar Crest Allentown, Pennsylvania 18103	Activo, no recluta
Lehigh Valley Hospital - Muhlenberg Bethlehem, Pennsylvania 18017	Activo, no recluta
Bryn Mawr Hospital Bryn Mawr, Pennsylvania 19010	Activo, no recluta
Main Line Health Center-Collegeville Collegeville, Pennsylvania 19426	Activo, no recluta
Centro Médico Geisinger Danville, Pensilvania 17822	Activo, no recluta
Pocono Medical Center East Stroudsburg, Pennsylvania 18301	Activo, no recluta
Main Line Health Center-Exton Exton, Pennsylvania 19341	Activo, no recluta
Geisinger Medical Center-Cancer Center Hazleton Hazleton, Pennsylvania 18201	Activo, no recluta
Lehigh Valley Hospital-Hazleton Hazleton, Pennsylvania 18201	Activo, no recluta
Oncología Médica Geisinger-Lewisburg Lewisburg, Pensilvania 17837	Activo, no recluta
Lewistown Hospital Lewistown, Pennsylvania 17044	Activo, no recluta
Riddle Memorial Hospital Media, Pennsylvania 19063	Activo, no recluta
Bryn Mawr Health Center Newtown Square, Pennsylvania 19073	Activo, no recluta
Paoli Memorial Hospital Paoli, Pennsylvania 19301	Activo, no recluta
Fox Chase Cancer Center Philadelphia, Pennsylvania 19111	Activo, no recluta
Temple University Hospital Philadelphia, Pennsylvania 19140	Activo, no recluta
Pottstown Hospital Pottstown, Pennsylvania 19464	Activo, no recluta
Geisinger Cancer Services-Pottsville Pottsville, Pennsylvania 17901	Activo, no recluta
Community Medical Center Scranton, Pennsylvania 18510	Activo, no recluta
Geisinger Medical Oncology-Selinsgrove Selinsgrove, Pennsylvania 17870	Activo, no recluta
Geisinger Medical Group State College, Pennsylvania 16801	Activo, no recluta
Reading Hospital West Reading, Pennsylvania 19611	Activo, no recluta
Centro Oncológico Geisinger Wyoming Valley/Henry Wilkes-Barre, Pensilvania 18711	Activo, no recluta
Lankenau Medical Center Wynnewood, Pennsylvania 19096	Activo, no recluta
Kent Hospital Warwick, Rhode Island 02886	Activo, no recluta
Saint Joseph's/Candler - Bluffton Campus Bluffton, South Carolina 29910	Activo, no recluta
South Carolina Cancer Specialists PC Hilton Head Island, South Carolina 29926-3827	Activo, no recluta
Levine Cancer Institute-Rock Hill Rock Hill, South Carolina 29732	Activo, no recluta
Memorial Hospital Chattanooga, Tennessee 37404	Activo, no recluta
Pulmonary Medicine Center of Chattanooga-Hixson Hixson, Tennessee 37343	Activo, no recluta
Memorial GYN Plus Ooltewah, Tennessee 37363	Activo, no recluta
Houston Methodist San Jacinto Hospital Baytown, Texas 77521	Activo, no recluta
Saint Joseph Regional Cancer Center Bryan, Texas 77802	Activo, no recluta
Parkland Memorial Hospital Dallas, Texas 75235	Activo, no recluta
UT Southwestern/Simmons Cancer Center-Dallas Dallas, Texas 75390	Activo, no recluta
UT Southwestern/Simmons Cancer Center-Fort Worth Fort Worth, Texas 76104	Activo, no recluta
Hospital Metodista de Houston Houston, Texas 77030	Activo, no recluta
Centro Oncológico M D Anderson Houston, Texas 77030	Activo, no recluta
Methodist Willowbrook Hospital Houston, Texas 77070	Activo, no recluta
UT Southwestern Clinical Center at Richardson/Plano Richardson, Texas 75080	Activo, no recluta
Scott and White Healthcare Round Rock Round Rock, Texas 78665	Activo, no recluta
Houston Methodist Sugar Land Hospital Sugar Land, Texas 77479	Activo, no recluta
Scott and White Memorial Hospital Temple, Texas 76508	Activo, no recluta
American Fork Hospital / Huntsman Intermountain Cancer Center American Fork, Utah 84003	Activo, no recluta
Sandra L Maxwell Cancer Center Cedar City, Utah 84720	Activo, no recluta
Farmington Health Center Farmington, Utah 84025	Activo, no recluta
Logan Regional Hospital Logan, Utah 84321	Activo, no recluta
Intermountain Medical Center Murray, Utah 84107	Activo, no recluta
McKay-Dee Hospital Center Ogden, Utah 84403	Activo, no recluta
Utah Valley Regional Medical Center Provo, Utah 84604	Activo, no recluta
Riverton Hospital Riverton, Utah 84065	Activo, no recluta
Dixie Medical Center Regional Cancer Center Saint George, Utah 84770	Activo, no recluta
Utah Cancer Specialists-Salt Lake City Salt Lake City, Utah 84106	Activo, no recluta
Instituto Huntsman del Cáncer/Universidad de Utah Salt Lake City, Utah 84112	Activo, no recluta
LDS Hospital Salt Lake City, Utah 84143	Activo, no recluta
South Jordan Health Center South Jordan, Utah 84009	Activo, no recluta
Norris Cotton Cancer Center-North Saint Johnsbury, Vermont 05819	Activo, no recluta
Providence Regional Cancer System-Aberdeen Aberdeen, Washington 98520	Activo, no recluta
MultiCare Auburn Medical Center Auburn, Washington 98001	Activo, no recluta
Overlake Medical Center Bellevue, Washington 98004	Activo, no recluta
PeaceHealth Saint Joseph Medical Center Bellingham, Washington 98225	Activo, no recluta
Harrison HealthPartners Hematology and Oncology-Bremerton Bremerton, Washington 98310	Activo, no recluta
Harrison Medical Center Bremerton, Washington 98310	Activo, no recluta
Highline Medical Center-Main Campus Burien, Washington 98166	Activo, no recluta
Providence Regional Cancer System-Centralia Centralia, Washington 98531	Activo, no recluta
Swedish Cancer Institute-Edmonds Edmonds, Washington 98026	Activo, no recluta
Saint Elizabeth Hospital Enumclaw, Washington 98022	Activo, no recluta
Providence Regional Cancer Partnership Everett, Washington 98201	Activo, no recluta
Saint Francis Hospital Federal Way, Washington 98003	Activo, no recluta
MultiCare Gig Harbor Medical Park Gig Harbor, Washington 98335	Activo, no recluta
Swedish Cancer Institute-Issaquah Issaquah, Washington 98029	Activo, no recluta
Kadlec Clinic Hematology and Oncology Kennewick, Washington 99336	Activo, no recluta
Providence Regional Cancer System-Lacey Lacey, Washington 98503	Activo, no recluta
Saint Clare Hospital Lakewood, Washington 98499	Activo, no recluta
PeaceHealth Saint John Medical Center Longview, Washington 98632	Activo, no recluta
Jefferson Healthcare Port Townsend, Washington 98368	Activo, no recluta
Harrison HealthPartners Hematology and Oncology-Poulsbo Poulsbo, Washington 98370	Activo, no recluta
MultiCare Good Samaritan Hospital Puyallup, Washington 98372	Activo, no recluta
Centro Médico Valley Renton, Washington 98055	Activo, no recluta
Pacific Gynecology Specialists Seattle, Washington 98104	Activo, no recluta
Swedish Medical Center-Ballard Campus Seattle, Washington 98107	Activo, no recluta
Kaiser Permanente Washington Seattle, Washington 98112	Activo, no recluta
Swedish Medical Center-First Hill Seattle, Washington 98122-4307	Activo, no recluta
Swedish Medical Center-Cherry Hill Seattle, Washington 98122-5711	Activo, no recluta
PeaceHealth United General Medical Center Sedro-Woolley, Washington 98284	Activo, no recluta
Providence Regional Cancer System-Shelton Shelton, Washington 98584	Activo, no recluta
MultiCare Deaconess Cancer and Blood Specialty Center - Valley Spokane Valley, Washington 99216	Activo, no recluta
MultiCare Deaconess Cancer and Blood Specialty Center - Downtown Spokane, Washington 99204	Activo, no recluta
MultiCare Deaconess Cancer and Blood Specialty Center - North Spokane, Washington 99218	Activo, no recluta
Franciscan Research Center-Northwest Medical Plaza Tacoma, Washington 98405	Activo, no recluta
Mary Bridge Children's Hospital and Health Center Tacoma, Washington 98405	Activo, no recluta
MultiCare Tacoma General Hospital Tacoma, Washington 98405	Activo, no recluta
Northwest Medical Specialties PLLC Tacoma, Washington 98405	Activo, no recluta
PeaceHealth Southwest Medical Center Vancouver, Washington 98664	Activo, no recluta
Providence Saint Mary Regional Cancer Center Walla Walla, Washington 99362	Activo, no recluta
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital Yakima, Washington 98902	Activo, no recluta
Providence Regional Cancer System-Yelm Yelm, Washington 98597	Activo, no recluta
United Hospital Center Bridgeport, West Virginia 26330	Activo, no recluta
Edwards Comprehensive Cancer Center Huntington, West Virginia 25701	Activo, no recluta
WVUH-Berkely Medical Center Martinsburg, West Virginia 25401	Activo, no recluta
West Virginia University Healthcare Morgantown, West Virginia 26506	Activo, no recluta
Camden Clark Medical Center Parkersburg, West Virginia 26101	Activo, no recluta
Duluth Clinic Ashland Ashland, Wisconsin 54806	Activo, no recluta
Northwest Wisconsin Cancer Center Ashland, Wisconsin 54806	Activo, no recluta
Marshfield Clinic-Chippewa Center Chippewa Falls, Wisconsin 54729	Activo, no recluta
Marshfield Medical Center-EC Cancer Center Eau Claire, Wisconsin 54701	Activo, no recluta
Mercyhealth Hospital and Cancer Center - Janesville Janesville, Wisconsin 53548	Activo, no recluta
Gundersen Lutheran Medical Center La Crosse, Wisconsin 54601	Activo, no recluta
Marshfield Clinic - Ladysmith Center Ladysmith, Wisconsin 54848	Activo, no recluta
Marshfield Medical Center-Marshfield Marshfield, Wisconsin 54449	Activo, no recluta
Marshfield Clinic-Minocqua Center Minocqua, Wisconsin 54548	Activo, no recluta
Cancer Center of Western Wisconsin New Richmond, Wisconsin 54017	Activo, no recluta
Marshfield Medical Center-Rice Lake Rice Lake, Wisconsin 54868	Activo, no recluta
Marshfield Clinic Stevens Point Center Stevens Point, Wisconsin 54482	Activo, no recluta
Marshfield Clinic-Wausau Center Wausau, Wisconsin 54401	Activo, no recluta
Marshfield Medical Center - Weston Weston, Wisconsin 54476	Activo, no recluta
Marshfield Clinic - Wisconsin Rapids Center Wisconsin Rapids, Wisconsin 54494	Activo, no recluta
Cheyenne Regional Medical Center-West Cheyenne, Wyoming 82001	Activo, no recluta
Billings Clinic-Cody Cody, Wyoming 82414	Activo, no recluta
Welch Cancer Center Sheridan, Wyoming 82801	Activo, no recluta
Puerto Rico
Advance Oncology Center Aguadilla 00603	Activo, no recluta
Doctor's Cancer Center-Arecibo Arecibo 00614	Activo, no recluta
Cancer Center-Metro Medical Center Bayamon Bayamon 00959-5060	Activo, no recluta
Hematologia Oncologia San Pablo Bayamon 00961	Activo, no recluta
HIMA San Pablo Oncologic Hospital Caguas 00726	Activo, no recluta
Doctors Cancer Center Manati 00674	Activo, no recluta
Instituto Oncologia Moderna Ponce Ponce 00716	Activo, no recluta
San Juan Community Oncology Group San Juan 00917	Activo, no recluta
Primary Care Physician Group San Juan 00920	Activo, no recluta
Centro Comprensivo de Cancer de UPR San Juan 00927	Activo, no recluta
San Juan City Hospital San Juan 00936	Activo, no recluta
Centro de Hematologia y Oncologia del Sur Santa Isabel 00757	Activo, no recluta

Criterios de inclusión

Criterios de inclusión:

* STEP 1 INITIAL REGISTRATION: HER2 TESTING
* Patients must have histologically or cytologically documented adenocarcinoma of the colon or rectum that is metastatic or locally advanced and unresectable
* Mutation results:

* All patients must have molecular testing performed in a Clinical Laboratory Improvement Act (CLIA) certified lab which includes which includes KRAS and NRAS gene and exon 15 of BRAF gene (BRAF V600E mutation); patients with any known activating mutation in exon 2 [codons 12 and 13], exon 3 [codons 59 and 61] and exon 4 [codons 117 and 146]) of KRAS/NRAS genes and in exon 15 (BRAFV600E mutation) of BRAF gene are not eligible
* Patients must not have been treated with any of the following prior to step 1 initial registration:

* Cetuximab, panitumumab, or any other monoclonal antibody against EGFR or inhibitor of EGFR
* HER-2 targeting for treatment of colorectal cancer; patients who have received prior trastuzumab or pertuzumab for other indications such as prior history of adjuvant or neoadjuvant breast cancer treatment prior to the development of advanced colorectal cancer are eligible
* Patients must not have had history of severe toxicity and intolerance to or hypersensitivity to irinotecan or any other study drug; patients must not have had a severe infusion-related reaction during any prior therapy with pertuzumab or trastuzumab
* Patients must have tumor slides available for submission for HER-2 testing; HER-2 testing must be completed by the central lab prior to step 2 randomization
* Patients must be informed of the investigational nature of this study and must sign and give informed consent in accordance with institutional and federal guidelines; for step 1 initial registration, the appropriate consent form is the step 1 consent form
* As a part of the OPEN registration process the treating institution's identity is provided in order to ensure that the current (within 365 days) date of institutional review board approval for this study has been entered in the system
* STEP 2 RANDOMIZATION
* Patients must have HER-2 amplification as determined by central testing (3+ or 2+ by immunohistochemistry and HER-2 gene amplification by in situ hybridization with a ratio of HER-2 gene signals to centromere 17 signals >= 2.0)
* Patients must have measurable disease that is metastatic or locally advanced and unresectable; imaging used to assess all disease per RECIST 1.1 must have been completed within 28 days prior to step 2 randomization; all disease must be assessed and documented on the Baseline Tumor Assessment Form
* Patients must have had at least one prior regimen of systemic chemotherapy for metastatic or locally advanced, unresectable disease; patients must have progressed following the most recent therapy; prior treatment with irinotecan is allowed; for patients that received adjuvant chemotherapy: prior treatment for metastatic disease is not required for patient who experienced disease recurrence during or within 6 months of completion of adjuvant chemotherapy; if the patient received one line of adjuvant treatment and had disease recurrence after 6 months of completing chemotherapy, patients will only be eligible after failing one additional line of chemotherapy used to treat the metastatic or locally advanced, unresectable disease; patients who have received >= 3 lines of systemic chemotherapy for metastatic or locally advanced, unresectable disease are not eligible
* Patients must have completed prior chemotherapy, immunotherapy, or radiation therapy at least 14 days prior to step 2 randomization and all toxicity must be resolved to Common Terminology Criteria for Adverse Events (CTCAE) version (v)4.0 grade 1 (with the exception of CTCAE v4.0 grade 2 neuropathy) prior to step 2 randomization
* Brain metastases are allowed if they have been adequately treated with radiotherapy or surgery and stable for at least 30 days prior to step 2 randomization; eligible patients must be neurologically asymptomatic and without corticosteroid treatment for at least 7 days prior to step 2 randomization
* Patients must have a Zubrod performance status of 0 or 1
* Patients must have a complete physical examination and medical history within 28 days prior to step 2 randomization
* Absolute neutrophil count (ANC) >= 1,500/mcL
* Plaquetas >= 75.000/mcL
* Hemoglobin >= 9 g/dL
* Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) both =< 5 x institutional upper limit of normal (IULN)
* Bilirubin =< 1.5 mg/dL * Calculated creatinine clearance > 30 ml/min within 14 days prior to step 2 randomization
* Patients who have had an echocardiogram performed within 6 months prior to step 2 randomization must have ventricular ejection fraction (left ventricular ejection fraction [LVEF]) >= 50% or >= within normal limits for the institution
* Patients must not have an uncontrolled intercurrent illness including, but not limited to diabetes, hypertension, severe infection, severe malnutrition, unstable angina, class III-IV New York Heart Association (NYHA) congestive heart failure, ventricular arrhythmias, active ischemic heart disease, or myocardial infarction within 6 months prior to step 2 randomization
* Patients must not have any known previous or concurrent condition suggesting susceptibility to hypersensitivity or allergic reactions, including, but not limited to: known hypersensitivity to any of the study treatments or to excipients of recombinant human or humanized antibodies; patients with mild or seasonal allergies may be included after discussion with the study chairs
* Patients must not be planning treatment with other systemic anti-cancer agents (e.g., chemotherapy, hormonal therapy, immunotherapy) or other treatments not part of protocol-specified anti-cancer therapy including concurrent investigational agents of any type
* No prior malignancy is allowed except for adequately treated basal cell or squamous cell skin cancer, in situ cervical cancer, ductal carcinoma in situ, other low grade lesions such as incidental appendix carcinoid, or any other cancer from which the patient has been disease and treatment free for two years; prostate cancer patients on active surveillance are eligible
* Patients must not be pregnant or nursing; females of child-bearing potential must have a negative serum pregnancy test within 7 days prior to registration; women/men of reproductive potential must have agreed to use an effective contraceptive method while on study and for at least 7 months after the last dose of study treatment; a woman is considered to be of "reproductive potential" if she has had menses at any time in the preceding 12 consecutive months; in addition to routine contraceptive methods, "effective contraception" also includes heterosexual celibacy and surgery intended to prevent pregnancy (or with a side-effect of pregnancy prevention) defined as a hysterectomy, bilateral oophorectomy or bilateral tubal ligation; however, if at any point a previously celibate patient chooses to become heterosexually active during the time period for use of contraceptive measures outlined in the protocol, he/she is responsible for beginning contraceptive measures
* Patients must be given the opportunity to consent to the optional submission of tissue for future research
* Patients must be informed of the investigational nature of this study and must sign and give written informed consent in accordance with institutional and federal guidelines; the appropriate consent form for this registration is the step 2 consent form
* STEP 2 RANDOMIZATION: As a part of the Oncology Patient Enrollment Network (OPEN) registration process the treating institution's identity is provided in order to ensure that the current (within 365 days) date of institutional review board approval for this study has been entered in the system
* STEP 3 CROSSOVER REGISTRATION (OPTIONAL): Patients must have documented disease progression while on CETIRI (Arm 2) on this protocol; the Follow-up Tumor Assessment Form documenting disease progression must be submitted to Southwest Oncology Group (SWOG) prior to step 3 crossover registration; registration to step 3 crossover must be within 28 days of discontinuation of CETIRI protocol treatment; patients going off treatment for any other reason are not eligible
* STEP 3 CROSSOVER REGISTRATION (OPTIONAL): Patients must have a Zubrod performance status of 0 or 1
* STEP 3 CROSSOVER REGISTRATION (OPTIONAL): ANC >= 1,500/mcL
* STEP 3 CROSSOVER REGISTRATION (OPTIONAL): Platelets >= 75,000/mcL
* STEP 3 CROSSOVER REGISTRATION (OPTIONAL): Hemoglobin >= 9 g/dL
* STEP 3 CROSSOVER REGISTRATION (OPTIONAL): AST and ALT both =< 5 x institutional upper limit of normal (IULN)
* STEP 3 CROSSOVER REGISTRATION (OPTIONAL): Bilirubin =< 1.5 mg/dL * STEP 3 CROSSOVER REGISTRATION (OPTIONAL): Calculated creatinine clearance > 30 ml/min within 14 days prior to step 3 crossover registration
* STEP 3 CROSSOVER REGISTRATION (OPTIONAL): Patients must have left ventricular ejection fraction (LVEF) >= 50% or >= lower limit of normal for the institution by echocardiogram within 14 days prior to step 3 crossover registration
* STEP 3 CROSSOVER REGISTRATION (OPTIONAL): Patients must have a magnesium, potassium, calcium, sodium, bicarbonate, and chloride performed within 14 days prior to step 3 crossover registration
* STEP 3 CROSSOVER REGISTRATION (OPTIONAL): Patients must be informed of the investigational nature of this study and must sign and give written informed consent in accordance with institutional and federal guidelines; the appropriate consent form for this registration is the step 2 consent form
* STEP 3 CROSSOVER REGISTRATION (OPTIONAL): As a part of the OPEN registration process the treating institution's identity is provided in order to ensure that the current (within 365 days) date of institutional review board approval for this study has been entered in the system

NCT ID

NCT03365882

Fecha en que se añadió el juicio

2017-12-07

Fecha de actualización

2025-03-25