{"id":213930,"date":"2022-09-05T23:05:54","date_gmt":"2022-09-06T03:05:54","guid":{"rendered":"https:\/\/fightcolorectalcancer.org\/nuevas-directrices-sobre-las-pruebas-de-biomarcadores\/"},"modified":"2026-06-17T19:21:38","modified_gmt":"2026-06-17T23:21:38","slug":"nuevas-directrices-sobre-las-pruebas-de-biomarcadores","status":"publish","type":"post","link":"https:\/\/fightcolorectalcancer.org\/es\/nuevas-directrices-sobre-las-pruebas-de-biomarcadores\/","title":{"rendered":"Nuevas directrices sobre las pruebas de biomarcadores"},"content":{"rendered":"\n

Los expertos en investigaci\u00f3n de Fight Colorectal Cancer (Fight CRC) han dado su opini\u00f3n sobre unas nuevas directrices basadas en la evidencia que abordan las pruebas de biomarcadores, centr\u00e1ndose menos en el tipo de c\u00e1ncer o el origen del tumor y m\u00e1s en la metodolog\u00eda y el estado del biomarcador. La gu\u00eda, titulada \u00abPruebas de reparaci\u00f3n de desajustes (MMR) e inestabilidad de microsat\u00e9lites (MSI) para el<\/a> tratamiento con inhibidores de puntos de control inmunitario\u00bb, la public\u00f3 el Colegio Americano de Pat\u00f3logos (CAP)<\/a> en colaboraci\u00f3n con la Asociaci\u00f3n de Patolog\u00eda Molecular<\/a>, la Sociedad Americana de Oncolog\u00eda Cl\u00ednica (ASCO)<\/a> y Fight CRC. Seg\u00fan el CAP, la gu\u00eda \u00ababre nuevos caminos con recomendaciones sobre el papel de la carga mutacional tumoral en las pruebas de MMR y la evaluaci\u00f3n del s\u00edndrome de Lynch, un s\u00edndrome de c\u00e1ncer hereditario que puede detectarse de forma inesperada en el estudio de estos pacientes con c\u00e1nceres avanzados\u00bb. <\/p>\n

Los biomarcadores del c\u00e1ncer son entidades biol\u00f3gicas, qu\u00edmicas o biof\u00edsicas que est\u00e1n presentes en los tejidos tumorales o en los fluidos corporales, y pueden aportar informaci\u00f3n valiosa sobre las caracter\u00edsticas de un tumor. Conocer c\u00f3mo se comportar\u00e1 el tumor en el futuro puede ayudar a los pacientes y a sus m\u00e9dicos a decidir cu\u00e1l es el mejor plan de tratamiento. <\/p>\n

Dos de las estrategias que se describen en el informe \u00abPath to a Cure\u00bb<\/a> de Fight CRC consisten en desarrollar campa\u00f1as de formaci\u00f3n para profesionales sanitarios y pacientes, y reforzar la alineaci\u00f3n con las medidas de calidad y acreditaci\u00f3n a trav\u00e9s de la Red Nacional Integral contra el C\u00e1ncer (NCCN) y la Comisi\u00f3n contra el C\u00e1ncer. Gracias a las nuevas directrices del CAP sobre pruebas de biomarcadores, la comunidad dedicada al c\u00e1ncer colorrectal se acerca m\u00e1s a las medidas de acreditaci\u00f3n descritas en \u00abPath to a Cure\u00bb. <\/p>\n

\u00abEsto supone un verdadero avance para los pacientes\u00bb,<\/em> afirm\u00f3 Anjee Davis, presidenta de Fight CRC. \u00abUno de nuestros principales objetivos en nuestro informe \u201cPath to a Cure\u201d es aumentar las pruebas de biomarcadores y moleculares. La nueva gu\u00eda de la CAP nos acerca un paso m\u00e1s a nuestro \u201cPath to a Cure\u201d\u00bb.<\/em><\/p>


Seg\u00fan la CAP, \u00abLa gu\u00eda \u201cPruebas de reparaci\u00f3n de desajustes (MMR) e inestabilidad de microsat\u00e9lites (MSI<\/a>) para el tratamiento con inhibidores de puntos de control inmunitario\u00bb ofrece claridad a los pat\u00f3logos y onc\u00f3logos para mejorar la evaluaci\u00f3n de pacientes con c\u00e1ncer colorrectal, de endometrio, gastroesof\u00e1gico, de intestino delgado y otros tipos de c\u00e1ncer que puedan ser candidatos a las inmunoterapias conocidas como inhibidores de puntos de control inmunitario\u00bb.<\/p>

Wendy Lewis y Wenora Johnson, defensoras de la investigaci\u00f3n de Fight CRC, colaboraron en la publicaci\u00f3n de las directrices.<\/p>

\u00abComo superviviente de tres c\u00e1nceres a la que le diagnosticaron el s\u00edndrome de Lynch, estoy muy orgullosa de haber trabajado en las gu\u00edas cl\u00ednicas sobre las pruebas de reparaci\u00f3n de desajustes y de inestabilidad de microsat\u00e9lites para el tratamiento con inhibidores de puntos de control inmunitario\u00bb, dijo Johnson. \u00abSaber que puedo cambiar mi pron\u00f3stico a largo plazo ante cualquier c\u00e1ncer adicional asociado al s\u00edndrome de Lynch me hace ver la supervivencia al c\u00e1ncer de una forma totalmente diferente. Lo que esto significa para los pacientes es que, gracias a estas gu\u00edas basadas en la evidencia, es posible que podamos tener una mejor calidad y cantidad de vida\u00bb. <\/p>

Fight CRC ofrece recursos gratuitos y revisados por m\u00e9dicos para garantizar que los pacientes se sometan a pruebas m\u00e1s eficaces y puedan defender mejor sus intereses. A principios de este a\u00f1o, el Dr. Richard Goldberg, miembro de la junta directiva de Fight CRC, junto con otros defensores de los pacientes, public\u00f3 un art\u00edculo de opini\u00f3n sobre la importancia de las pruebas de biomarcadores en The Cancer Letter. Lee el art\u00edculo<\/a>. <\/p>\n","protected":false},"excerpt":{"rendered":"

Los defensores de la investigaci\u00f3n de Fight Colorectal Cancer (Fight CRC) han dado su opini\u00f3n sobre unas nuevas directrices basadas en la evidencia que abordan las pruebas de biomarcadores, centr\u00e1ndose menos en el tipo de c\u00e1ncer o el origen del tumor y m\u00e1s en la metodolog\u00eda y el estado del biomarcador. La directriz <\/p>\n","protected":false},"author":3,"featured_media":213932,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[635],"tags":[],"class_list":["post-213930","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sala-de-prensa"],"acf":[],"yoast_head":"\nNuevas directrices sobre las pruebas de biomarcadores - Fight Colorectal Cancer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/fightcolorectalcancer.org\/es\/nuevas-directrices-sobre-las-pruebas-de-biomarcadores\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Nuevas directrices sobre las pruebas de biomarcadores - Fight Colorectal Cancer\" \/>\n<meta property=\"og:description\" content=\"Los defensores de la investigaci\u00f3n de Fight Colorectal Cancer (Fight CRC) han dado su opini\u00f3n sobre unas nuevas directrices basadas en la evidencia que abordan las pruebas de biomarcadores, centr\u00e1ndose menos en el tipo de c\u00e1ncer o el origen del tumor y m\u00e1s en la metodolog\u00eda y el estado del biomarcador. 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