{"id":213174,"date":"2026-05-08T20:12:48","date_gmt":"2026-05-09T00:12:48","guid":{"rendered":"https:\/\/fightcolorectalcancer.org\/%e9%9d%9e%e8%bd%ac%e7%a7%bb%e6%80%a7%e8%82%9b%e9%97%a8%e7%99%8c%e5%8e%9f%e5%8f%91%e6%89%8b%e6%9c%af%e5%8f%8a%e6%80%bb%e7%94%9f%e5%ad%98%e6%9c%9f%e7%9a%84%e8%b6%8b%e5%8a%bf%ef%bc%9a%e4%b8%80%e9%a1%b9\/"},"modified":"2026-06-17T19:08:55","modified_gmt":"2026-06-17T23:08:55","slug":"%e9%9d%9e%e8%bd%ac%e7%a7%bb%e6%80%a7%e8%82%9b%e9%97%a8%e7%99%8c%e5%8e%9f%e5%8f%91%e6%89%8b%e6%9c%af%e5%8f%8a%e6%80%bb%e7%94%9f%e5%ad%98%e6%9c%9f%e7%9a%84%e8%b6%8b%e5%8a%bf%ef%bc%9a%e4%b8%80%e9%a1%b9","status":"publish","type":"post","link":"https:\/\/fightcolorectalcancer.org\/zh-hans\/%e9%9d%9e%e8%bd%ac%e7%a7%bb%e6%80%a7%e8%82%9b%e9%97%a8%e7%99%8c%e5%8e%9f%e5%8f%91%e6%89%8b%e6%9c%af%e5%8f%8a%e6%80%bb%e7%94%9f%e5%ad%98%e6%9c%9f%e7%9a%84%e8%b6%8b%e5%8a%bf%ef%bc%9a%e4%b8%80%e9%a1%b9\/","title":{"rendered":"\u975e\u8f6c\u79fb\u6027\u809b\u95e8\u764c\u539f\u53d1\u624b\u672f\u53ca\u603b\u751f\u5b58\u671f\u7684\u8d8b\u52bf\uff1a\u4e00\u9879\u57fa\u4e8e\u4eba\u7fa4\u7684\u5206\u6790"},"content":{"rendered":"<div>\n<p>\u300a\u80bf\u7624\u5b66\u5bb6\u300b. 2026\u5e745\u67088\u65e5;31(6):oyag148. doi: 10.1093\/oncolo\/oyag148.  <\/p>\n<p><b>\u6458\u8981<\/b><\/p>\n<p>\u80cc\u666f\uff1a\u7f8e\u56fd\u809b\u95e8\u764c\u53d1\u75c5\u7387\u5448\u4e0a\u5347\u8d8b\u52bf\uff0c\u76ee\u524d\u6bcf\u5e74\u75c5\u4f8b\u6570\u5df2\u8d85\u8fc710 000\u4f8b\u3002 \u5316\u653e\u7597\uff08CRT\uff09\u662f\u6cbb\u7597\u975e\u8f6c\u79fb\u6027\u809b\u95e8\u9cde\u72b6\u7ec6\u80de\u764c\uff08SCCA\uff09\u7684\u6807\u51c6\u6839\u6cbb\u6027\u6cbb\u7597\u65b9\u6848\uff0c\u624b\u672f\u901a\u5e38\u4ec5\u7528\u4e8e\u5bf9\u6cbb\u7597\u65e0\u53cd\u5e94\u4e14\u75be\u75c5\u6301\u7eed\u5b58\u5728\u6216\u8fdb\u5c55\u7684\u60a3\u8005\u3002 \u8fd1\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4f18\u5316\u4e86\u6cbb\u7597\u65b9\u6848\uff0c\u652f\u6301\u5728\u8003\u8651\u624b\u672f\u524d\u4e8e\u7b2c26\u5468\u8bc4\u4f30\u6cbb\u7597\u53cd\u5e94\u3002\u7136\u800c\uff0c\u5f53\u524d\u4eba\u7fa4\u5c42\u9762\u4e2d upfront \u521d\u6b21\u624b\u672f\u7684\u6a21\u5f0f\u53ca\u5176\u76f8\u5173\u7684\u751f\u5b58\u8d8b\u52bf\u4ecd\u672a\u5f97\u5230\u5145\u5206\u63cf\u8ff0\u3002   <\/p>\n<p>\u65b9\u6cd5\uff1a\u5229\u7528\u76d1\u6d4b\u3001\u6d41\u884c\u75c5\u5b66\u548c\u6700\u7ec8\u7ed3\u679c\uff08SEER\uff09\u767b\u8bb0\u7cfb\u7edf\uff082004-2020\u5e74\uff09\uff0c\u6211\u4eec\u7b5b\u9009\u51fa\u65b0\u8bca\u65ad\u4e3a\u975e\u8f6c\u79fb\u6027\u809b\u95e8\u9cde\u72b6\u7ec6\u80de\u80bf\u7624\uff08ICD-O-3 8050-8089\uff09\u7684\u6210\u5e74\u60a3\u8005\u3002 \u7814\u7a76\u7ed3\u5c40\u5305\u62ec\u662f\u5426\u63a5\u53d7\u539f\u53d1\u624b\u672f\u4f5c\u4e3a\u521d\u59cb\u6cbb\u7597\u4ee5\u53ca\u603b\u751f\u5b58\u671f\u3002\u6211\u4eec\u8bc4\u4f30\u4e86\u65f6\u95f4\u8d8b\u52bf\uff08Cochran-Armitage\u68c0\u9a8c\uff09\u3001\u4e0e\u539f\u53d1\u624b\u672f\u76f8\u5173\u7684\u56e0\u7d20\uff08\u591a\u53d8\u91cf\u903b\u8f91\u56de\u5f52\u5206\u6790\uff09\u4ee5\u53ca\u968f\u65f6\u95f4\u63a8\u79fb\u7684\u751f\u5b58\u60c5\u51b5\uff08Kaplan-Meier\u751f\u5b58\u5206\u6790\uff1b\u591a\u53d8\u91cfCox\u6bd4\u4f8b\u98ce\u9669\u6a21\u578b\uff09\u3002  <\/p>\n<p>\u7ed3\u679c\uff1a\u572816 718\u4f8b\u975e\u8f6c\u79fb\u6027\u809b\u7ba1\u764c\u60a3\u8005\u4e2d\uff0c33.1%\uff08n = 5529\uff09\u63a5\u53d7\u4e86\u521d\u6b21\u624b\u672f\uff0c83.7%\uff08n = 13 997\uff09\u4f5c\u4e3a\u521d\u59cb\u6cbb\u7597\u7684\u4e00\u90e8\u5206\u63a5\u53d7\u4e86\u653e\u7597\u3002 \u9996\u9009\u624b\u672f\u7684\u6bd4\u4f8b\u4ece2004\u5e74\u768446.0%\u4e0b\u964d\u81f32020\u5e74\u768428.7%\uff08\u8d8b\u52bfP < 0.001\uff09\uff0c\u800c\u653e\u7597\u7684\u5e94\u7528\u7387\u968f\u65f6\u95f4\u63a8\u79fb\u76f8\u5bf9\u7a33\u5b9a\uff08\u8d8b\u52bfP = 0.106\uff09\u3002 \u5728\u8c03\u6574\u540e\u7684\u5206\u6790\u4e2d\uff0c\u5e74\u9f84\u8f83\u8f7b\uff08<50 \u5c81 vs 60-69 \u5c81\uff1bOR 1.614\uff09\u3001\u7537\u6027\uff08OR 1.508\uff09\u4ee5\u53ca\u975e\u897f\u73ed\u7259\u88d4\u9ed1\u4eba\uff08\u4e0e\u975e\u897f\u73ed\u7259\u88d4\u767d\u4eba\u76f8\u6bd4\uff1b OR 1.178\uff09\u4e0e\u63a5\u53d7\u9996\u9009\u624b\u672f\u7684\u51e0\u7387\u8f83\u9ad8\u76f8\u5173\u3002\u80bf\u7624\u56e0\u7d20\u4e0e\u624b\u672f\u4f7f\u7528\u5b58\u5728\u663e\u8457\u5173\u8054\uff08\u4f8b\u5982\uff0cT1 \u4e0e T2 \u76f8\u6bd4\uff1aOR 3.072\uff1bN \u5206\u671f\u8d8a\u9ad8\uff0c\u63a5\u53d7\u624b\u672f\u7684\u51e0\u7387\u8d8a\u4f4e\uff09\u3002 \u603b\u4f53\u751f\u5b58\u7387\u5728\u4e0d\u540c\u8bca\u65ad\u65f6\u671f\u5448\u73b0\u6539\u5584\u8d8b\u52bf\uff08log-rank P = 0.0002\uff09\uff1b\u5728\u8c03\u6574\u540e\u7684Cox\u6a21\u578b\u4e2d\uff0c2016-2020\u5e74\u786e\u8bca\uff08\u4e0e2004-2007\u5e74\u76f8\u6bd4\uff09\u4e0e\u8f83\u4f4e\u7684\u6b7b\u4ea1\u98ce\u9669\u76f8\u5173\uff08HR 0.77\uff09\u3002    <\/p>\n<p>\u7ed3\u8bba\uff1a2004\u5e74\u81f32020\u5e74\u95f4\uff0c\u4f5c\u4e3a\u975e\u8f6c\u79fb\u6027\u809b\u95e8\u764c\u521d\u59cb\u6cbb\u7597\u65b9\u6848\u7684\u521d\u6b21\u624b\u672f\u7387\u663e\u8457\u4e0b\u964d\uff0c\u8fd9\u4e0e\u5316\u653e\u7597\uff08CRT\uff09\u5e94\u7528\u7387\u7684\u4e0a\u5347\u8d8b\u52bf\u4e00\u81f4\uff0c\u800c\u603b\u4f53\u751f\u5b58\u7387\u5219\u968f\u65f6\u95f4\u63a8\u79fb\u6709\u6240\u63d0\u9ad8\u3002\u5728\u7279\u5b9a\u4e9a\u7ec4\u4e2d\u4ecd\u6301\u7eed\u91c7\u7528\u521d\u6b21\u624b\u672f\u7684\u505a\u6cd5\uff0c\u9700\u8981\u8fdb\u4e00\u6b65\u7814\u7a76\u4ee5\u660e\u786e\u5176\u9002\u5e94\u75c7\uff0c\u5e76\u786e\u4fdd\u6cbb\u7597\u7b26\u5408\u6307\u5357\u8981\u6c42\u3002 <\/p>\n<p>PMID:<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42101873\/?utm_source=SimplePie&#038;utm_medium=rss&#038;utm_campaign=pubmed-2&#038;utm_content=1zCzv8cgXYLTFpYKqcnmEQSRKKzgHYU2epGXR7qqB04ouFsEtP&#038;fc=20260305170338&#038;ff=20260508201247&#038;v=2.20.0\">42101873<\/a>| DOI:<a href=\"https:\/\/doi.org\/10.1093\/oncolo\/oyag148\">10.1093\/oncolo\/oyag148<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>\u300a\u80bf\u7624\u5b66\u5bb6\u300b. 2026\u5e745\u67088\u65e5;31(6):oyag148. doi: 10.1093\/oncolo\/oy [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"rop_custom_images_group":[],"rop_custom_messages_group":[],"rop_publish_now":"initial","rop_publish_now_accounts":[],"rop_publish_now_history":[],"rop_publish_now_status":"pending","footnotes":""},"categories":[640],"tags":[],"class_list":["post-213174","post","type-post","status-publish","format-standard","hentry","category-research"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ 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