{"id":213833,"date":"2022-01-13T14:26:23","date_gmt":"2022-01-13T19:26:23","guid":{"rendered":"https:\/\/fightcolorectalcancer.org\/%e5%8c%96%e7%96%97%e6%9c%9f%e9%97%b4%e7%9a%84%e5%86%b0%e6%95%b7\/"},"modified":"2026-06-17T19:20:41","modified_gmt":"2026-06-17T23:20:41","slug":"%e5%8c%96%e7%96%97%e6%9c%9f%e9%97%b4%e7%9a%84%e5%86%b0%e6%95%b7","status":"publish","type":"post","link":"https:\/\/fightcolorectalcancer.org\/zh-hans\/%e5%8c%96%e7%96%97%e6%9c%9f%e9%97%b4%e7%9a%84%e5%86%b0%e6%95%b7\/","title":{"rendered":"\u5316\u7597\u671f\u95f4\u7684\u201c\u51b0\u6577\u201d"},"content":{"rendered":"\n<p>\u5728\u708e\u70ed\u7684\u590f\u65e5\u91cc\uff0c\u5bf9\u8bb8\u591a\u4eba\u6765\u8bf4\uff0c\u4e00\u676f\u51b0\u9547\u67e0\u6aac\u6c34\u6216\u4e00\u6839\u51b0\u68d2\u7b80\u76f4\u662f\u5b8c\u7f8e\u7684\u4eab\u53d7\u3002\u4f46\u5982\u679c\u4f60\u6b63\u5728\u63a5\u53d7\u67d0\u4e9b\u5316\u7597\u65b9\u6848\uff0c\u4e14\u5bf9\u5bd2\u51b7\u654f\u611f\uff0c\u8fd9\u79cd\u51b0\u51c9\u7684\u96f6\u98df\u53ef\u80fd\u4f1a\u8ba9\u4f60\u89c9\u5f97\u5b83\u662f\u4f60\u7684\u5934\u53f7\u654c\u4eba\u3002 <\/p>\n<p>\u8bb8\u591a\u7ed3\u76f4\u80a0\u764c\u60a3\u8005\u63a5\u53d7\u4e00\u79cd\u540d\u4e3aFOLFOX\u7684\u8054\u5408\u836f\u7269\u6cbb\u7597\uff0c\u8be5\u65b9\u6848\u5305\u62ec\u5965\u6c99\u5229\u94c2\u3001\u4e9a\u53f6\u9178\u548c\u6c1f\u5c3f\u5627\u5576\u3002 \u5176\u4e2d\uff0c\u5965\u6c99\u5229\u94c2\u5c24\u5176\u4ee5\u4f1a\u589e\u52a0\u60a3\u8005\u5bf9\u5bd2\u51b7\u7684\u654f\u611f\u6027\u800c\u8457\u79f0\u3002\u5b83\u4f1a\u5f15\u8d77\u9ebb\u6728\u3001\u523a\u75db\u548c\u808c\u8089\u75c9\u631b\uff0c\u800c\u63a5\u89e6\u4f4e\u6e29\u73af\u5883\u6216\u63a5\u89e6\u51b7\u7269\u4f53\u4f1a\u52a0\u5267\u8fd9\u4e9b\u75c7\u72b6\u3002  <\/p>\n<p>\u7136\u800c\uff0c\u6700\u663e\u8457\u7684\u526f\u4f5c\u7528\u662f\u53e3\u8154\u548c\u54bd\u5589\u90e8\u4f4d\u51fa\u73b0\u7684\u77ed\u671f\u795e\u7ecf\u635f\u4f24\uff0c\u8fd9\u4f1a\u5bfc\u81f4\u6cbb\u7597\u540e\u7684\u51e0\u5929\u5185\u96be\u4ee5\u8fdb\u98df\u6216\u996e\u7528\u4efb\u4f55\u51b7\u98df\u51b7\u996e\u3002 \u6b64\u5916\uff0cFOLFOX\u65b9\u6848\u5e38\u4f1a\u5bfc\u81f4\u5316\u7597\u5f15\u8d77\u7684\u5468\u56f4\u795e\u7ecf\u75c5\u53d8\uff08CIPN\uff09\u3002CIPN\u662f\u4e00\u79cd\u53d1\u751f\u5728\u624b\u811a\u4e0a\u7684\u8fdb\u884c\u6027\u75c5\u53d8\uff0c\u6709\u65f6\u4e0d\u53ef\u9006\u3002\u60a3\u8005\u5e38\u5c06\u5176\u63cf\u8ff0\u4e3a\u9ebb\u6728\u3001\u523a\u75db\u548c\u75bc\u75db\uff0c\u8fd8\u4f1a\u5bfc\u81f4\u5bf9\u5bd2\u51b7\u7684\u654f\u611f\u3002   <\/p>\n<p><em>\u201c\u5728\u63a5\u53d7\u4e8612\u4e2a\u7597\u7a0b\u7684Folfox\u5316\u7597\u540e\uff0c\u6211\u4e00\u541e\u4e0b\u4efb\u4f55\u51b7\u7684\u4e1c\u897f\uff0c\u5c31\u4f1a\u611f\u5230\u5f3a\u70c8\u7684\u51b7\u523a\u6fc0\uff08\u5c31\u50cf\u541e\u4e0b\u51b0\u5c51\u4e00\u6837\uff09\u3002<\/em>\u201d\u2014\u2014\u5b89\u5fb7\u70c8\u5a05\u00b7\u8fea\u80af\uff0cIV\u671f\u7ed3\u80a0\u764c\u60a3\u8005<\/p><h2>\u201c\u51b0\u6577\u201d\u53ef\u80fd\u6709\u5e2e\u52a9<\/h2>\n<p>\u51e0\u5341\u5e74\u6765\uff0c\u60a3\u8005\u4e00\u76f4\u5c06\u8fd9\u4e9b\u4ee4\u4eba\u4e0d\u9002\u7684\u526f\u4f5c\u7528\u89c6\u4e3a\u764c\u75c7\u6cbb\u7597\u4e2d\u4e0d\u53ef\u907f\u514d\u7684\u4e00\u90e8\u5206\u3002\u7136\u800c\uff0c\u60a3\u8005\u4eec\u6b63\u5728\u5e7f\u4e3a\u4f20\u64ad\u4f7f\u7528\u51b0\u5757\u6765\u7f13\u89e3\u754f\u5bd2\u75c7\u72b6\u7684\u597d\u5904\u3002\u5c3d\u7ba1\u8fd9\u4f3c\u4e4e\u6709\u6096\u5e38\u7406\uff0c\u4f46\u7814\u7a76\u8868\u660e\uff0c\u8fd9\u79cd\u65b9\u6cd5\u6216\u8bb8\u786e\u5b9e\u6709\u6548\u3002  <\/p>\n<p>2019\u5e744\u6708\u53d1\u8868\u5728<a href=\"https:\/\/jnccn.org\/view\/journals\/jnccn\/17\/4\/article-p358.xml\" target=\"_blank\" rel=\"noopener\">\u300a\u7f8e\u56fd\u56fd\u5bb6\u7efc\u5408\u764c\u75c7\u7f51\u7edc\u6742\u5fd7\u300b\u4e0a<\/a>\u7684\u4e00\u9879\u7814\u7a76\u8868\u660e\uff0c\u5728\u63a5\u53d7\u5965\u6c99\u5229\u94c2\u8f93\u6ce8\u671f\u95f4\u5c06\u51b0\u5757\u542b\u5728\u53e3\u4e2d\u7684\u80c3\u80a0\u9053\u764c\u75c7\u60a3\u8005\uff08\u6709\u4e9b\u4eba\u79f0\u4e4b\u4e3a\u201c\u51b0\u6577\u6cd5\u201d\uff09\uff0c\u5176\u53e3\u8154\u5bf9\u51b7\u523a\u6fc0\u7684\u654f\u611f\u5ea6\u4f4e\u4e8e\u6cbb\u7597\u671f\u95f4\u672a\u5c06\u51b0\u5757\u542b\u5728\u53e3\u4e2d\u7684\u60a3\u8005\u3002 \u6b64\u4e3e\u7684\u597d\u5904\u5728\u4e8e\uff0c\u8fd9\u4e9b\u60a3\u8005\u5728\u8fdb\u98df\u548c\u996e\u6c34\u65f6\u4f1a\u611f\u5230\u8f83\u5c11\u7684\u4e0d\u9002\u3002 <\/p>\n<p><em>\u201c\u76ee\u524d\u6211\u6b63\u5728\u63a5\u53d7CapOx\u6cbb\u7597\uff0c\u5df2\u662f\u7b2c5\u4e2a\u7597\u7a0b\uff0c\u73b0\u5728\u6b63\u5728\u51b0\u6577\u3002\u548c\u4ee5\u524d\u76f8\u6bd4\u7b80\u76f4\u5929\u5dee\u5730\u522b\uff01\u73b0\u5728\u6211\u7ec8\u4e8e\u80fd\u559d\u51b7\u996e\u4e86\u3002<\/em>\u201d\u2014\u2014\u5b89\u5fb7\u70c8\u5a05\u00b7\u8fea\u80af\uff0cIV\u671f\u7ed3\u80a0\u764c\u60a3\u8005<\/p><h2>COLONTOWN \u7684\u201cIcing Protocol\u201d<\/h2>\n<p>\u901a\u8fc7\u4e2a\u4eba\u7ecf\u9a8c\u5206\u4eab\uff0cCOLONTOWN\u201cLive Wire\u201dFacebook\u5728\u7ebf\u7fa4\u7ec4\u4e2d\u7684\u60a3\u8005\u5f00\u59cb\u5c1d\u8bd5\u5404\u81ea\u7684\u51b0\u6577\u65b9\u6848\uff0c\u5e76\u62a5\u544a\u4e86\u6210\u529f\u7684\u6cbb\u7597\u6548\u679c\u3002 \u8be5\u65b9\u6848\u5305\u62ec\u5728\u5f00\u59cb\u5965\u6c99\u5229\u94c2\u6cbb\u7597\u524d10\u5206\u949f\u8fdb\u884c\u51b0\u6577\uff0c\u5e76\u5728\u6574\u4e2a\u8f93\u6db2\u8fc7\u7a0b\u4e2d\u4ee5\u53ca\u8f93\u6db2\u7ed3\u675f\u540e20\u5206\u949f\u5185\uff0c\u5c06\u51b7\u6577\u5305\u6577\u4e8e\u624b\u811a\uff0c\u5e76\u542b\u670d\u6216\u5480\u56bc\u51b0\u5757\u3001\u51b0\u68d2\u6216\u51b0\u9547\u996e\u6599\u7b49\u51b7\u98df\u3002\u8be5\u7fa4\u7ec4\u4e2d\u7684\u8bb8\u591a\u6210\u5458\u5747\u53cd\u9988\u8be5\u65b9\u6848\u53d6\u5f97\u4e86\u79ef\u6781\u6548\u679c\u3002  <\/p>\n<p>COLONTOWN\u7684\u9886\u5bfc\u56e2\u961f\u57282020\u5e74\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u5e74\u4f1a\u4e0a\u53d1\u8868<a href=\"https:\/\/meetings.asco.org\/abstracts-presentations\/188651\" target=\"_blank\" rel=\"noopener\">\u4e86\u4e00\u7bc7\u5173\u4e8e\u60a3\u8005\u793e\u7fa4\u529b\u91cf\u53ca\u51b0\u6577\u6280\u5de7\u7684\u6458\u8981<\/a>\u3002 \u6839\u636e\u4ed6\u4eec\u7684\u7ed3\u8bba\uff0c\u201c\u8fd9\u4e00\u73b0\u5b9e\u6848\u4f8b\u51f8\u663e\u4e86\u53d7\u8fc7\u6559\u80b2\u7684\u60a3\u8005\u5021\u5bfc\u8005\u5728\u793e\u4ea4\u5a92\u4f53\u4e0a\u7684\u4f5c\u7528\u3002\u4e0e\u8fd9\u4e9b\u7fa4\u4f53\u76f4\u63a5\u5408\u4f5c\uff0c\u53ef\u4ee5\u4e3a\u533b\u5b66\u754c\u63d0\u4f9b\u6d1e\u89c1\uff0c\u5e2e\u52a9\u4e86\u89e3\u60a3\u8005\u53ef\u4ee5\u91c7\u53d6\u54ea\u4e9b\u63aa\u65bd\u6765\u9884\u9632\u5316\u7597\u76f8\u5173\u7684\u526f\u4f5c\u7528\u3002\u201d <\/p>\n<p><em>\u201c\u770b\u5230\u5728FOLFOX\u8f93\u6db2\u671f\u95f4\u56bc\u51b0\u5757\u8fd9\u6837\u7b80\u5355\u7684\u4e8b\u60c5\uff0c\u7adf\u80fd\u5bf9\u7ed3\u76f4\u80a0\u764c\u60a3\u8005\u5728\u5316\u7597\u671f\u95f4\u7684\u751f\u6d3b\u8d28\u91cf\u4ea7\u751f\u5982\u6b64\u5927\u7684\u5f71\u54cd\uff0c\u8fd9\u4ee4\u4eba\u632f\u594b\u3002\u5728\u6b64\u4e4b\u524d\uff0c\u6211\u4eec\u66fe\u7aed\u5c3d\u5168\u529b\u907f\u514d\u63a5\u89e6\u4efb\u4f55\u51b7\u7684\u4e1c\u897f\u3002 \u73b0\u5728\uff0c\u6709\u4e9b\u60a3\u8005\u751a\u81f3\u4f1a\u5728\u79bb\u5f00\u8f93\u6db2\u4e2d\u5fc3\u540e\u76f4\u63a5\u53bb\u4e70\u51b0\u6dc7\u6dcb\uff01\u6211\u6700\u671f\u5f85\u770b\u5230\u51b0\u6577\u5728\u51cf\u8f7b\u5316\u7597\u6027\u5468\u56f4\u795e\u7ecf\u75c5\u53d8\uff08CIPN\uff09\u65b9\u9762\u53ef\u80fd\u4ea7\u751f\u7684\u957f\u671f\u6548\u679c\u3002\u8fd9\u5145\u5206\u5c55\u73b0\u4e86\u5728\u53d7\u8fc7\u6559\u80b2\u7684\u793e\u4ea4\u5a92\u4f53\u73af\u5883\u4e2d\uff0c\u60a3\u8005\u6240\u5177\u5907\u7684\u5f71\u54cd\u529b\u3002\u201d<\/em>\u2014\u2014\u8fbe\u5a1c\u00b7\u5361\u8fea\u7eb3\u65af\u533b\u751f\uff0c\u9000\u4f11\u8db3\u75c5\u533b\u751f\uff0cIIIc\u671f\u7ed3\u76f4\u80a0\u764c\u5e78\u5b58\u8005<\/p><h2>\u51b7\u51bb\u7597\u6cd5\u5e76\u975e\u65b0\u4e8b\u7269<\/h2>\n<p>\u5728\u764c\u75c7\u6cbb\u7597\u4e2d\u5bf9\u7279\u5b9a\u8eab\u4f53\u90e8\u4f4d\u8fdb\u884c\u51b7\u5374\u7684\u60f3\u6cd5\uff0c\u5728\u764c\u75c7\u6cbb\u7597\u9886\u57df\u5e76\u975e\u5b8c\u5168\u65b0\u9c9c\u3002\u4e00\u98792017\u5e74\u7684\u7814\u7a76\u8868\u660e\uff0c\u63a5\u53d7\u7d2b\u6749\u7c7b\u836f\u7269\u3001\u84bd\u73af\u7c7b\u836f\u7269\u6216\u4e24\u8005\u8054\u5408\u5316\u7597\u7684\u4e73\u817a\u764c\u5973\u6027\u60a3\u8005\uff0c\u82e5\u8fdb\u884c<a href=\"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2601500\" target=\"_blank\" rel=\"noopener\">\u5934\u76ae\u51b7\u5374<\/a>\uff0c\u5176\u8131\u53d1\u7387\u4f4e\u4e8e50%\u7684\u53ef\u80fd\u6027\u663e\u8457\u9ad8\u4e8e\u672a\u8fdb\u884c\u5934\u76ae\u51b7\u5374\u7684\u60a3\u8005\u3002 <\/p>\n<p>\u53e6\u4e00\u9879\u9488\u5bf9\u4e73\u817a\u764c\u60a3\u8005\u7684\u7814\u7a76<a href=\"https:\/\/academic.oup.com\/jnci\/article\/110\/2\/141\/4443215\" target=\"_blank\" 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