Clinical Trial Finder Search Results

About the Fight CRC Clinical Trial Finder

This Trial Finder is a one-stop place to find and learn more about high-impact clinical trials for colorectal cancer patients with advanced colon or rectal cancer. Originally created by the late Dr. Tom Marsilje as a curated spreadsheet of trials, the FightCRC’s Trial Finder is a resource to find research studies that are open in your geography, and for which you may be eligible. The current data is now for metastatic, stage IV patients with both MSS and MSI-H status. The list of trials here is sourced from the ClinicalTrials.gov website and curated with Comments and Helpful Links. The searches can be focused on immunotherapy-centered trials and narrowed to studies enrolling patients who already have received immunotherapies.

Medical Disclaimer

The information contained in this website is not intended to recommend the self management of health problems, medical conditions or wellness. It is not intended to endorse or recommend any particular type of medical treatment, physician or treatment facility. Should any reader have any health care related questions, promptly call or consult your physician or healthcare provider. The information contained in this website should NOT be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Fight Colorectal Cancer disclaims any liability based on information provided in this website.

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NCT ID	Title	Phase	Date Added	Location	Prior IO Allowed	CRC-directed	Status	Drugs	Tags
NCT ID NCT04014530	TitlePembrolizumab With Ataluren in Patients With Metastatic pMMR and dMMR Colorectal Carcinoma or Metastatic dMMR Endometrial Carcinoma: the ATAPEMBRO Study	Phase Phase 1	Date Added 2019-07-10	Location Netherlands	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs Ataluren + Pembrolizumab, Keytruda	Tags MSS/ MMRp
NCT ID NCT04009681	TitleA Study Evaluating Safety and Therapeutic Activity of THOR-707 in Adult Subjects With Advanced or Metastatic Solid Tumors	Phase Phase 1, Phase 2	Date Added 2019-07-05	Location Arizona, United States Colorado, United States Florida, United States Tennessee, United States Texas, United States Argentina Australia Chile Singapore Spain	Prior IO Allowed No	CRC-directed No	Status Terminated	Drugs anti-EGFR antibody, Checkpoint inhibitor, THOR-707	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT04008030	TitleA Study of Nivolumab, Nivolumab Plus Ipilimumab, or Investigator’s Choice Chemotherapy for the Treatment of Participants With Deficient Mismatch Repair (dMMR)/Microsatellite Instability High (MSI-H) Metastatic Colorectal Cancer (mCRC) ( CheckMate 8HW )	Phase Phase 3	Date Added 2019-07-05	Location California, United States Colorado, United States Illinois, United States New York, United States Oregon, United States Pennsylvania, United States Texas, United States Virginia, United States Argentina Australia Austria Belgium Brazil Canada Chile China Czechia Denmark France Germany Greece Ireland Italy Japan Netherlands Norway Puerto Rico Romania Spain Turkey (Türkiye) United Kingdom	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs Bevacizumab, cetuximab, fluorouracil, Irinotecan, Leucovorin, oxaliplatin	Tags MSI-H/ MMRd
NCT ID NCT04003792	TitleTreatment With Hepatic Arterial Infusion of Oxaliplatin in Combination With Systemic FOLFIRI Chemotherapy and Bevacuzimab in Patients With Liver-only Colorectal Liver Metastases (CRLM): Conversion to Complete Resection in Patients With Initially Inoperable Liver-only CRLM.	Phase Phase 2	Date Added 2019-07-01	Location Israel	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs Bevacizumab, FOLFIRI Protocol, oxaliplatin	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03994601	TitleAn Investigational Immunotherapy Study of BMS-986288 Alone and in Combination With Nivolumab in Advanced Solid Cancers	Phase Phase 1	Date Added 2019-06-21	Location California, United States Colorado, United States Maryland, United States Missouri, United States New Jersey, United States Argentina Canada Chile France Italy Spain	Prior IO Allowed Yes	CRC-directed No	Status Active, not recruiting	Drugs BMS-986288, Nivolumab, Opdivo	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03990233	TitleA Trial of BI 765063 Monotherapy and in Combination With BI 754091 in Patients With Advanced Solid Tumours	Phase Phase 1	Date Added 2019-06-18	Location Belgium France	Prior IO Allowed Yes	CRC-directed No	Status Completed	Drugs BI 754091, BI 765063	Tags MSS/ MMRp
NCT ID NCT03985891	TitleThe Efficacy of JS001 Combined With Chemotherapy in Patients With Locally Advanced Colon Cancer	Phase Phase 1/Phase 2	Date Added 2019-06-14	Location China	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs Anti-PD-1 Monoclonal Antibody JS001, Chemotherapy	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03984578	TitleWindow of Opportunity Study in Colorectal Cancer	Phase Phase 2	Date Added 2019-06-13	Location Singapore	Prior IO Allowed No	CRC-directed Yes	Status Completed	Drugs Capecitabine/ 5-FU, CapeOX, Pembrolizumab, Eloxatin, Keytruda	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03983993	TitleNiraparib and Panitumumab in Patients With Advanced or Metastatic Colorectal Cancer	Phase Phase 2	Date Added 2019-06-12	Location Georgia, United States	Prior IO Allowed Yes	CRC-directed Yes	Status Active, not recruiting	Drugs Niraparib, panitumumab, Vectibix, Zejula	Tags MSS/ MMRp
NCT ID NCT03981146	TitleA Phase II Trial Assessing Nivolumab in Class II Expressing Microsatellite Stable Colorectal Cancer	Phase Phase 2	Date Added 2019-06-10	Location United Kingdom	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs Nivolumab, Opdivo	Tags MSS/ MMRp

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