Clinical Trial Finder Search Results

About the Fight CRC Clinical Trial Finder

This Trial Finder is a one-stop place to find and learn more about high-impact clinical trials for colorectal cancer patients with advanced colon or rectal cancer. Originally created by the late Dr. Tom Marsilje as a curated spreadsheet of trials, the FightCRC’s Trial Finder is a resource to find research studies that are open in your geography, and for which you may be eligible. The current data is now for metastatic, stage IV patients with both MSS and MSI-H status. The list of trials here is sourced from the ClinicalTrials.gov website and curated with Comments and Helpful Links. The searches can be focused on immunotherapy-centered trials and narrowed to studies enrolling patients who already have received immunotherapies.

Medical Disclaimer

The information contained in this website is not intended to recommend the self management of health problems, medical conditions or wellness. It is not intended to endorse or recommend any particular type of medical treatment, physician or treatment facility. Should any reader have any health care related questions, promptly call or consult your physician or healthcare provider. The information contained in this website should NOT be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Fight Colorectal Cancer disclaims any liability based on information provided in this website.

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NCT ID	Title	Phase	Date Added	Location	Prior IO Allowed	CRC-directed	Status	Drugs	Tags
NCT ID NCT06788171	TitlePULSAR Combined With PD-1 Ab and Chemotherapy Plus Bev. for CRLM	Phase Phase 2	Date Added 2025-03-25	Location China	Prior IO Allowed No	CRC-directed Yes	Status Not yet recruiting	Drugs	Tags MSS/ MMRp
NCT ID NCT06764680	TitleOral Chemotherapy, Targeted Therapy and Immunotherapy With/without Radiotherapy As 3rd- or Later-line Therapy for Advanced MSS/pMMR Colorectal Cancer	Phase Phase 2	Date Added 2025-01-08	Location China	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs	Tags MSS/ MMRp
NCT ID NCT06634875	TitleIsunakinra Alone and in Combination with Pembrolizumab in Patients with Colorectal Cancer (MSS)	Phase Phase 2	Date Added 2024-10-10	Location California, United States	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs	Tags MSS/ MMRp
NCT ID NCT06589440	TitlePhase 2 Study of SR-8541A in Combination With Botensilimab and Balstilimab in Subjects With Refractory Metastatic Microsatellite Stable Colorectal Cancer (MSS-CRC)	Phase Phase 2	Date Added 2024-09-19	Location New Jersey, United States Texas, United States Washington, United States	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs Balstilimab, Botensilimab	Tags MSS/ MMRp
NCT ID NCT06566755	TitleCadonilimab (AK104) Combined With Chemotherapy and Bevacizumab as First-line Treatment for RAS Mutated or Right Sided-metastatic MSS Colorectal Cancer	Phase Phase 3	Date Added 2024-08-22	Location China	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs	Tags MSS/ MMRp
NCT ID NCT06558773	TitleGSL Synthetase Inhibitor Plus Immune Checkpoint Inhibitor and/or Regorafenib in Previously Treated pMMR/MSS CRC.	Phase Phase 2	Date Added 2024-08-19	Location China	Prior IO Allowed Yes	CRC-directed Yes	Status Not yet recruiting	Drugs	Tags MSS/ MMRp
NCT ID NCT06515314	TitleHRYZ-T102 TCR-T Cell for AFP Positive Advanced HCC and Other Solid Tumors	Phase Phase 1	Date Added 2024-07-23	Location China	Prior IO Allowed Yes	CRC-directed No	Status Recruiting	Drugs	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT06514651	TitleMAQ-001 in Patients With Advanced Solid Tumors	Phase Phase 1	Date Added 2024-07-23	Location France	Prior IO Allowed Yes	CRC-directed No	Status Recruiting	Drugs	Tags MSI-H/ MMRd
NCT ID NCT06513221	TitleA Prospective Study of MSS-type Metastatic Colorectal Cancer Receiving Multiple Lines of Standard Chemotherapy, Bevacizumab Combined With Adebrelimab	Phase	Date Added 2024-07-22	Location	Prior IO Allowed No	CRC-directed Yes	Status	Drugs	Tags MSS/ MMRp
NCT ID NCT06508307	TitleA Phase I Clinical Study of Intratumoral Injection Oncolytic Vaccinia Virus GC001 in Patient With Advanced Solid Tumors	Phase Phase 1	Date Added 2024-07-18	Location China	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs	Tags MSI-H/ MMRd, MSS/ MMRp

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