Clinical Trial Finder Search Results

About the Fight CRC Clinical Trial Finder

This Trial Finder is a one-stop place to find and learn more about high-impact clinical trials for colorectal cancer patients with advanced colon or rectal cancer. Originally created by the late Dr. Tom Marsilje as a curated spreadsheet of trials, the FightCRC’s Trial Finder is a resource to find research studies that are open in your geography, and for which you may be eligible. The current data is now for metastatic, stage IV patients with both MSS and MSI-H status. The list of trials here is sourced from the ClinicalTrials.gov website and curated with Comments and Helpful Links. The searches can be focused on immunotherapy-centered trials and narrowed to studies enrolling patients who already have received immunotherapies.

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The information contained in this website is not intended to recommend the self management of health problems, medical conditions or wellness. It is not intended to endorse or recommend any particular type of medical treatment, physician or treatment facility. Should any reader have any health care related questions, promptly call or consult your physician or healthcare provider. The information contained in this website should NOT be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Fight Colorectal Cancer disclaims any liability based on information provided in this website.

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NCT ID	Title	Fase	Date Added	Ubicación	Prior IO Allowed	CRC-directed	Status	Drogas	Etiquetas
NCT ID NCT06010901	TitleA Clinical Study of TQB2618 Injection Monotherapy and Combination Regimen (With Penpulimab Injection ±Anlotinib Hydrochloride Capsules) in the Four or Later Lines of Treatment of Advanced Colorectal Cancer.	Fase Fase 1	Date Added 2023-08-25	Ubicación China	Prior IO Allowed Sí	CRC-directed Sí	Status Reclutamiento	Drogas Anlotinib hydrochloride capsules, Penpulimab Injection, TQB2618 injection	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT06011772	TitleA Phase 0 Study of EGF-Depleting Therapy CIMAvax-EGF in Combination With Standard Therapy for RAS- and BRAF Wild-Type Metastatic Colorectal Cancer	Fase Fase inicial 1	Date Added 2023-08-25	Ubicación New York, United States	Prior IO Allowed Sí	CRC-directed Sí	Status Suspendido	Drogas fluorouracil, Irinotecan, Leucovorin, oxaliplatin	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT06013111	TitleAn Exploratory Clinical Study Evaluating the Safety and Efficacy of Anti-CEA-CAR-T Cells Injection in Patients With CEA+ Locally Advanced and/or Metastatic Solid Tumors	Fase Fase 1	Date Added 2023-08-28	Ubicación China	Prior IO Allowed Sí	CRC-directed Sí	Status Reclutamiento	Drogas	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT06099821	TitleKN046 más regorafenib o apatinib en cánceres del aparato digestivo MSI-H resistentes al bloqueo de PD-1/PD-L1	Fase Fase 2	Date Added 2023-10-25	Ubicación China	Prior IO Allowed Sí	CRC-directed Sí	Status Reclutamiento	Drogas apatinib, KN046, Regorafenib	Etiquetas MSI-H/ MMRd
NCT ID NCT06102902	TitleTesting the Addition of Anti-cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment, Cetuximab Plus Encorafenib, for Refractory BRAF V600E mCRC	Fase Fase 1	Date Added 2023-10-26	Ubicación California, United States Kansas, United States Ohio, United States Oklahoma, United States Texas, United States Virginia, United States	Prior IO Allowed Sí	CRC-directed Sí	Status Reclutamiento	Drogas BET Bromodomain Inhibitor ZEN-3694, encorafenib	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT06105021	TitlePhase I Study of Autologous CD8+ and CD4+ Engineered T Cell Receptor T Cells in Subjects With Advanced or Metastatic Solid Tumor	Fase Phase 1, Phase 2	Date Added 2023-10-27	Ubicación California, United States Connecticut, United States New York, United States Oregon, United States Tennessee, United States Texas, United States Washington, United States Wisconsin, United States	Prior IO Allowed Sí	CRC-directed Sí	Status Reclutamiento	Drogas AFNT-211	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03223779	TitleEstudio de TAS-102 más radioterapia para el tratamiento del hígado en pacientes con metástasis hepáticas de cáncer colorrectal	Fase Fase 1	Date Added 2017-07-21	Ubicación Massachusetts, United States	Prior IO Allowed Sí	CRC-directed Sí	Status Reclutamiento	Drogas	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT06120127	TitlePostoperative Chemotherapy With/Without Radiotherapy and Immunotherapy for Colorectal Liver Metastases With High Risk of Locally Recurrence	Fase Fase 2	Date Added 2023-11-07	Ubicación China	Prior IO Allowed Sí	CRC-directed Sí	Status Reclutamiento	Drogas Chemotherapy, PD-1 antibody	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT06253520	TitleAutologous T-cells Genetically Engineered to Express Receptors Reactive Against KRAS Mutations in Conjunction With a Vaccine Directed Against These Antigens in Participants With Metastatic Cancer	Fase Fase 1	Date Added 2024-02-12	Ubicación Maryland, United States	Prior IO Allowed Sí	CRC-directed Sí	Status Reclutamiento	Drogas Aldesleukin, Cyclophosphamide, Fludarabine	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT06302062	TitlePhase I Clinical Study of Tumor-associated Lymph Node T Cell Therapy for Advanced Solid Tumors	Fase Fase 1	Date Added 2024-03-08	Ubicación China	Prior IO Allowed Sí	CRC-directed No	Status Reclutamiento	Drogas Cyclophosphamide, IL-2, Serplulimab Injection, Tumor Associated Lymph node T cell	Etiquetas MSI-H/ MMRd, MSS/ MMRp

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