Clinical Trial Finder Search Results

About the Fight CRC Clinical Trial Finder

This Trial Finder is a one-stop place to find and learn more about high-impact clinical trials for colorectal cancer patients with advanced colon or rectal cancer. Originally created by the late Dr. Tom Marsilje as a curated spreadsheet of trials, the FightCRC’s Trial Finder is a resource to find research studies that are open in your geography, and for which you may be eligible. The current data is now for metastatic, stage IV patients with both MSS and MSI-H status. The list of trials here is sourced from the ClinicalTrials.gov website and curated with Comments and Helpful Links. The searches can be focused on immunotherapy-centered trials and narrowed to studies enrolling patients who already have received immunotherapies.

Medical Disclaimer

The information contained in this website is not intended to recommend the self management of health problems, medical conditions or wellness. It is not intended to endorse or recommend any particular type of medical treatment, physician or treatment facility. Should any reader have any health care related questions, promptly call or consult your physician or healthcare provider. The information contained in this website should NOT be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Fight Colorectal Cancer disclaims any liability based on information provided in this website.

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NCT ID	Title	Phase	Date Added	Location	Prior IO Allowed	CRC-directed	Status	Drugs	Tags
NCT ID NCT03608046	TitleAvelumab Combined With Cetuximab and Irinotecan for Treatment Refractory Metastatic Colorectal Microsatellite Stable Cancer	Phase Phase 2	Date Added 2018-07-31	Location Belgium	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs Avelumab, Cetuximab Injection, Irinotecan	Tags MSS/ MMRp
NCT ID NCT03626922	TitleStudy of Pembrolizumab With Pemetrexed and Oxaliplatin in Chemo-Refractory Metastatic Colorectal Cancer Patients	Phase Phase 1	Date Added 2018-08-13	Location Florida, United States Illinois, United States Michigan, United States Minnesota, United States Pennsylvania, United States	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs Dexamethasone, oxaliplatin, Pembrolizumab, Pemetrexed, Alimta, Eloxatin, Keytruda	Tags MSS/ MMRp
NCT ID NCT03013218	TitleA Study of Evorpacept (ALX148) in Patients With Advanced Solid Tumors and Lymphoma (ASPEN-01)	Phase Phase 1	Date Added 2017-01-06	Location Colorado, United States Connecticut, United States Massachusetts, United States Michigan, United States Washington, United States Korea, Republic of	Prior IO Allowed No	CRC-directed No	Status Completed	Drugs 5-FU + Cisplatin, Evorpacept (ALX148), Pembrolizumab, Ramucirumab + Paclitaxel, Rituximab, Trastuzumab	Tags MSS/ MMRp
NCT ID NCT03638206	TitleAutologous CAR-T/TCR-T Cell Immunotherapy for Malignancies	Phase Phase 1/Phase 2	Date Added 2018-08-20	Location China	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs CAR-T cell immunotherapy	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03772561	TitlePhase I Study of AZD5363 + Olaparib + Durvalumab in Patients With Advanced or Metastatic Solid Tumor Malignancies	Phase Phase 1	Date Added 2018-12-11	Location Singapore	Prior IO Allowed No	CRC-directed No	Status Recruiting	Drugs AZD5363+Olaparib+Durvalumab	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT02343991	TitleBlood-Brain Barrier Disruption Using Transcranial MRI-Guided Focused Ultrasound	Phase Not Applicable	Date Added 2015-01-22	Location Canada	Prior IO Allowed No	CRC-directed No	Status Active, not recruiting	Drugs Transcranial ExABlate	Tags MSS/ MMRp
NCT ID NCT04991948	TitleStudy of Pembrolizumab Treatment After CYAD-101 With FOLFOX Preconditioning in Metastatic Colorectal Cancer	Phase Phase 1	Date Added 2021-08-05	Location Florida, United States Belgium	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs CYAD-101, FOLFOX, Pembrolizumab	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT05299840	TitleImpact of Using the Oncogramme(R) Device to Select the First Line of Treatment for Patients With Metastatic Colorectal Cancer	Phase Not Applicable	Date Added 2022-03-29	Location France	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03865082	TitleStudy of Tilsotolimod in Combination With Nivolumab and Ipilimumab for the Treatment of Solid Tumors (ILLUMINATE-206)	Phase Phase 2	Date Added 2019-03-06	Location Arizona, United States California, United States Texas, United States	Prior IO Allowed No	CRC-directed No	Status Active, not recruiting	Drugs Ipilimumab, Nivolumab, Tilsotolimod, Opdivo, Yervoy	Tags MSS/ MMRp
NCT ID NCT03366155	TitleHepatic Artery Infusion Pump Chemotherapy With Floxuridine and Dexamethasone in Combination With Systemic Chemotherapy for Patients With Colorectal Cancer Metastatic to the Liver	Phase Phase 2	Date Added 2017-12-08	Location Maryland, United States	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs 5FU, cetuximab, FUDR-Dex, Irinotecan, Medtronic SynchroMed II Pump with Codman 3000 Constant Flow Pump Catheter, OneRNA, oxaliplatin, panitumumab	Tags MSI-H/ MMRd, MSS/ MMRp

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