Clinical Trial Finder Search Results

About the Fight CRC Clinical Trial Finder

This Trial Finder is a one-stop place to find and learn more about high-impact clinical trials for colorectal cancer patients with advanced colon or rectal cancer. Originally created by the late Dr. Tom Marsilje as a curated spreadsheet of trials, the FightCRC’s Trial Finder is a resource to find research studies that are open in your geography, and for which you may be eligible. The current data is now for metastatic, stage IV patients with both MSS and MSI-H status. The list of trials here is sourced from the ClinicalTrials.gov website and curated with Comments and Helpful Links. The searches can be focused on immunotherapy-centered trials and narrowed to studies enrolling patients who already have received immunotherapies.

Medical Disclaimer

The information contained in this website is not intended to recommend the self management of health problems, medical conditions or wellness. It is not intended to endorse or recommend any particular type of medical treatment, physician or treatment facility. Should any reader have any health care related questions, promptly call or consult your physician or healthcare provider. The information contained in this website should NOT be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Fight Colorectal Cancer disclaims any liability based on information provided in this website.

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NCT ID	Title	Fase	Date Added	Ubicación	Prior IO Allowed	CRC-directed	Status	Drogas	Etiquetas
NCT ID NCT03519412	TitlePembrolizumab en cáncer colorrectal metastásico competente en MMR preparado farmacológicamente para desencadenar el estado de hipermutación	Fase Fase 2	Date Added 2018-05-09	Ubicación Italia	Prior IO Allowed No	CRC-directed Sí	Status Activo, no recluta	Drogas pembrolizumab (treatment), temozolomide (induction),, Keytruda, Temodar	Etiquetas MSS/ MMRp
NCT ID NCT02886585	TitlePembrolizumab In Central Nervous System Metastases	Fase Fase 2	Date Added 2016-09-01	Ubicación Massachusetts, United States	Prior IO Allowed No	CRC-directed No	Status Activo, no recluta	Drogas Pembrolizumab	Etiquetas MSS/ MMRp
NCT ID NCT04963283	TitleStudy of Cabozantinib and Nivolumab in Refractory Metastatic Microsatellite Stable (MSS) Colorectal Cancer	Fase Fase 2	Date Added 2021-07-15	Ubicación Colorado, United States	Prior IO Allowed No	CRC-directed Sí	Status Activo, no recluta	Drogas Cabozantinib, Nivolumab	Etiquetas MSS/ MMRp
NCT ID NCT03977090	TitleGeptanolimab(GB226) combinado con fruquintinib en el tratamiento del cáncer colorrectal metastásico	Fase Fase 1	Date Added 2019-06-06	Ubicación China	Prior IO Allowed No	CRC-directed Sí	Status Reclutamiento	Drogas Fruquintinib, Geptanolimab Injection, Elunate	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT02298959	TitleTesting the PD-1 Antibody, MK3475, Given With Ziv-aflibercept in Patients With Advanced Cancer	Fase Fase 1	Date Added 2014-11-24	Ubicación Florida, United States Maryland, United States Massachusetts, United States Canadá	Prior IO Allowed No	CRC-directed Sí	Status Activo, no recluta	Drogas Pembrolizumab, Ziv-Aflibercept, Keytruda, Zaltrap	Etiquetas MSS/ MMRp
NCT ID NCT03844750	TitlePembrolizumab After Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver and Who Are Undergoing Liver Surgery	Fase Fase 2	Date Added 2019-02-18	Ubicación California, United States	Prior IO Allowed No	CRC-directed Sí	Status Activo, no recluta	Drogas Pembrolizumab, Vactosertib, Keytruda	Etiquetas MSS/ MMRp
NCT ID NCT05243862	TitleSafety and Activity of PolyPEPI1018 Plus Atezolizumab in Colorectal Cancer.	Fase Fase 2	Date Added 2022-02-17	Ubicación Arizona, United States Florida, United States Minnesota, United States	Prior IO Allowed No	CRC-directed Sí	Status Activo, no recluta	Drogas Atezolizumab, PolyPEPI1018, Tecentriq	Etiquetas MSS/ MMRp
NCT ID NCT04776148	TitleStudy of Lenvatinib (MK-7902/E7080) in Combination With Pembrolizumab (MK-3475) Versus Standard of Care in Participants With Metastatic Colorectal Cancer (MK-7902-017/E7080-G000-325/LEAP-017)	Fase Fase 3	Date Added 2021-03-01	Ubicación California, United States Georgia, United States Illinois, United States Maryland, United States Michigan, United States Montana, United States Oregon, United States Pennsylvania, United States Virginia, United States Washington, United States Argentina Australia Canadá China Dinamarca Alemania Israel Japón Corea, República de Russian Federation España Taiwán Turkey Reino Unido	Prior IO Allowed No	CRC-directed Sí	Status Activo, no recluta	Drogas Lenvatinib, Pembrolizumab, Regorafenib, TAS-102 (trifluridine and tipiracil)	Etiquetas MSS/ MMRp
NCT ID NCT04653480	TitleSurufatinib, Toripalimab and Chemotherapy in Second-line MT and MSS CRC	Fase Fase 2	Date Added 2020-12-04	Ubicación China	Prior IO Allowed No	CRC-directed Sí	Status Reclutamiento	Drogas Chemotherapy, Surufatinib, Toripalimab	Etiquetas MSS/ MMRp
NCT ID NCT03925662	TitleMebendazol como tratamiento adyuvante del cáncer de colon	Fase Fase 3	Date Added 2019-04-24	Ubicación Egipto	Prior IO Allowed No	CRC-directed Sí	Status Reclutamiento	Drogas Folfox with avastin, Mebendazole	Etiquetas MSI-H/ MMRd, MSS/ MMRp

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