Clinical Trial Finder Search Results

About the Fight CRC Clinical Trial Finder

This Trial Finder is a one-stop place to find and learn more about high-impact clinical trials for colorectal cancer patients with advanced colon or rectal cancer. Originally created by the late Dr. Tom Marsilje as a curated spreadsheet of trials, the FightCRC’s Trial Finder is a resource to find research studies that are open in your geography, and for which you may be eligible. The current data is now for metastatic, stage IV patients with both MSS and MSI-H status. The list of trials here is sourced from the ClinicalTrials.gov website and curated with Comments and Helpful Links. The searches can be focused on immunotherapy-centered trials and narrowed to studies enrolling patients who already have received immunotherapies.

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The information contained in this website is not intended to recommend the self management of health problems, medical conditions or wellness. It is not intended to endorse or recommend any particular type of medical treatment, physician or treatment facility. Should any reader have any health care related questions, promptly call or consult your physician or healthcare provider. The information contained in this website should NOT be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Fight Colorectal Cancer disclaims any liability based on information provided in this website.

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NCT ID	Title	Fase	Date Added	Ubicación	Prior IO Allowed	CRC-directed	Status	Drogas	Etiquetas
NCT ID NCT05194735	TitleEstudio de fase I/II de células T autólogas que expresan receptores de células T (TCR) en sujetos con tumores sólidos	Fase Fase 1	Date Added 2022-01-18	Ubicación Texas, United States	Prior IO Allowed Sí	CRC-directed Sí	Status Activo, no recluta	Drogas Aldesleukin (IL-2), Neoantigen specific TCR-T cell drug product	Etiquetas MSS/ MMRp
NCT ID NCT05722327	TitlePhase I Trial of Adagrasib (MRTX849) in Combination With Cetuximab and Irinotecan in Patients With Colorectal Cancer	Fase Fase 1	Date Added 2023-02-10	Ubicación Texas, United States	Prior IO Allowed No	CRC-directed Sí	Status Activo, no recluta	Drogas cetuximab, Irinotecan, MRTX849	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03772561	TitlePhase I Study of AZD5363 + Olaparib + Durvalumab in Patients With Advanced or Metastatic Solid Tumor Malignancies	Fase Fase 1	Date Added 2018-12-11	Ubicación Singapur	Prior IO Allowed No	CRC-directed No	Status Reclutamiento	Drogas AZD5363+Olaparib+Durvalumab	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT06105021	TitlePhase I Study of Autologous CD8+ and CD4+ Engineered T Cell Receptor T Cells in Subjects With Advanced or Metastatic Solid Tumor	Fase Phase 1, Phase 2	Date Added 2023-10-27	Ubicación California, United States Connecticut, United States New York, United States Oregon, United States Tennessee, United States Texas, United States Washington, United States Wisconsin, United States	Prior IO Allowed Sí	CRC-directed Sí	Status Reclutamiento	Drogas AFNT-211	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT06302062	TitlePhase I Clinical Study of Tumor-associated Lymph Node T Cell Therapy for Advanced Solid Tumors	Fase Fase 1	Date Added 2024-03-08	Ubicación China	Prior IO Allowed Sí	CRC-directed No	Status Reclutamiento	Drogas Cyclophosphamide, IL-2, Serplulimab Injection, Tumor Associated Lymph node T cell	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT04793958	TitleEstudio de fase 3 de MRTX849 con cetuximab frente a quimioterapia en pacientes con cáncer colorrectal avanzado con mutación KRAS G12C (KRYSTAL-10)	Fase Fase 3	Date Added 2021-03-11	Ubicación Alabama, United States Arizona, United States Arkansas, United States California, United States Colorado, United States Connecticut, United States Florida, United States Georgia, United States Illinois, United States Indiana, United States Iowa, United States Louisiana, United States Maryland, United States Massachusetts, United States Michigan, United States Minnesota, United States Missouri, United States Nebraska, United States Nevada, United States New Jersey, United States New York, United States North Carolina, United States Ohio, United States Oklahoma, United States Pennsylvania, United States South Carolina, United States Tennessee, United States Texas, United States Utah, United States Virginia, United States Washington, United States West Virginia, United States Wisconsin, United States Argentina Australia Austria Bélgica Brasil Canadá China Colombia Czechia Dinamarca Finland Francia Alemania Greece Hong Kong Ireland Italia Corea, República de Malaysia Mexico Países Bajos Polonia Portugal Puerto Rico Romania Singapur España Taiwán Tailandia Ukraine Reino Unido	Prior IO Allowed Sí	CRC-directed Sí	Status Activo, no recluta	Drogas cetuximab, FOLFIRI Regimen, mFOLFOX6 Regimen, MRTX849	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT06589440	TitlePhase 2 Study of SR-8541A in Combination With Botensilimab and Balstilimab in Subjects With Refractory Metastatic Microsatellite Stable Colorectal Cancer (MSS-CRC)	Fase Fase 2	Date Added 2024-09-19	Ubicación New Jersey, United States Texas, United States Washington, United States	Prior IO Allowed No	CRC-directed Sí	Status Reclutamiento	Drogas Balstilimab, Botensilimab	Etiquetas MSS/ MMRp
NCT ID NCT05480306	TitlePhase 2 Study of DKN-01 in Colorectal Cancer	Fase Fase 2	Date Added 2022-07-29	Ubicación Arizona, United States California, United States Florida, United States Louisiana, United States Maryland, United States Missouri, United States New York, United States North Carolina, United States South Carolina, United States South Dakota, United States Tennessee, United States Washington, United States Wisconsin, United States Alemania Corea, República de	Prior IO Allowed No	CRC-directed Sí	Status Activo, no recluta	Drogas Bevacizumab, DKN-01, FOLFIRI, FOLFOX	Etiquetas MSS/ MMRp
NCT ID NCT06039202	TitleEstudio de fase 2 de CA102N combinado con TAS-102 comparado con bevacizumab combinado con TAS-102 en sujetos con cáncer colorrectal metastásico recidivante y/o refractario.	Fase Fase 2	Date Added 2023-09-15	Ubicación	Prior IO Allowed Sí	CRC-directed Sí	Status Aún no se ha contratado	Drogas CA102N, TAS-102	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT04046445	TitleEstudio de fase 1b para evaluar ATP128, VSV-GP128 y BI 754091, en pacientes con cáncer colorrectal en estadio IV	Fase Fase 1	Date Added 2019-08-06	Ubicación Arizona, United States California, United States Colorado, United States New York, United States North Carolina, United States Texas, United States Bélgica Alemania Suiza	Prior IO Allowed No	CRC-directed Sí	Status Activo, no recluta	Drogas ATP128, BI 754091, VSV-GP128	Etiquetas MSI-H/ MMRd, MSS/ MMRp

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