Clinical Trial Finder Search Results

About the Fight CRC Clinical Trial Finder

This Trial Finder is a one-stop place to find and learn more about high-impact clinical trials for colorectal cancer patients with advanced colon or rectal cancer. Originally created by the late Dr. Tom Marsilje as a curated spreadsheet of trials, the FightCRC’s Trial Finder is a resource to find research studies that are open in your geography, and for which you may be eligible. The current data is now for metastatic, stage IV patients with both MSS and MSI-H status. The list of trials here is sourced from the ClinicalTrials.gov website and curated with Comments and Helpful Links. The searches can be focused on immunotherapy-centered trials and narrowed to studies enrolling patients who already have received immunotherapies.

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The information contained in this website is not intended to recommend the self management of health problems, medical conditions or wellness. It is not intended to endorse or recommend any particular type of medical treatment, physician or treatment facility. Should any reader have any health care related questions, promptly call or consult your physician or healthcare provider. The information contained in this website should NOT be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Fight Colorectal Cancer disclaims any liability based on information provided in this website.

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NCT ID	Title	Fase	Date Added	Ubicación	Prior IO Allowed	CRC-directed	Status	Drogas	Etiquetas
NCT ID NCT03785249	TitleEstudio de fase 1/2 de MRTX849 en pacientes con cáncer que presentan una mutación KRAS G12C KRYSTAL-1	Fase Fase 1	Date Added 2018-12-24	Ubicación Alabama, United States Alaska, United States Arizona, United States California, United States Colorado, United States Connecticut, United States Delaware, United States Florida, United States Georgia, United States Illinois, United States Indiana, United States Iowa, United States Kansas, United States Kentucky, United States Louisiana, United States Maine, United States Maryland, United States Massachusetts, United States Michigan, United States Minnesota, United States Missouri, United States Montana, United States Nebraska, United States Nevada, United States New York, United States North Carolina, United States Ohio, United States Oklahoma, United States Oregon, United States Pennsylvania, United States South Carolina, United States Tennessee, United States Texas, United States Virginia, United States Washington, United States Wisconsin, United States Puerto Rico	Prior IO Allowed Sí	CRC-directed Sí	Status Reclutamiento	Drogas afatinib, cetuximab, MRTX849, Pembrolizumab	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT06066424	TitlePhase 1 Dose Escalation and Expansion Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Patients With Advanced Solid Tumors (TROPIKANA)	Fase Fase 1	Date Added 2023-10-04	Ubicación Texas, United States	Prior IO Allowed Sí	CRC-directed No	Status Reclutamiento	Drogas Cyclophosphamide, Fludarabine Phosphate, Rimiducid, TROP2-CAR-NK Cells	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID PG545 (pixatimod) in combination with nivolumab	TitlePG545 (pixatimod) in combination with nivolumab	Fase Fase 1	Date Added 2019-04-26	Ubicación	Prior IO Allowed Sí	CRC-directed Sí	Status Reclutamiento	Drogas	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT06841159	TitlePersonalized Ultrafractionated Stereotactic Adaptive Radiotherapy (PULSAR ) Combined With Anti-PD1，Chemotherapy and Target Therapy for Metastatic Colorectal Cancer	Fase Fase 2	Date Added 2025-03-25	Ubicación China	Prior IO Allowed No	CRC-directed Sí	Status Reclutamiento	Drogas	Etiquetas MSS/ MMRp
NCT ID NCT05349890	TitlePersonalized TCR-T: Study of Adoptively Transferred T-cell Receptor Gene-engineered T Cells (TCR-T)	Fase Fase 1	Date Added 2022-04-27	Ubicación Oregon, United States	Prior IO Allowed Sí	CRC-directed No	Status Activo, no recluta	Drogas CDX-1140, Pembrolizumab, Keytruda	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT02600949	TitleVacuna peptídica personalizada para el tratamiento de pacientes con cáncer de páncreas o colorrectal avanzado	Fase Fase 1	Date Added 2015-11-09	Ubicación Texas, United States	Prior IO Allowed Sí	CRC-directed Sí	Status Reclutamiento	Drogas imiquimod, Pembrolizumab, Sotigalimab, Synthetic Tumor-Associated Peptide Vaccine Therapy	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03568058	TitlePersonalized Immunotherapy in Adults With Advanced Cancers Immunotherapy in Adults With Advanced Cancers	Fase Fase 1	Date Added 2018-06-26	Ubicación California, United States	Prior IO Allowed Sí	CRC-directed No	Status Activo, no recluta	Drogas Pembrolizumab, personalized vaccine, Keytruda	Etiquetas MSS/ MMRp
NCT ID NCT04096417	TitlePemigatinib for the Treatment of Metastatic or Unresectable Colorectal Cancer Harboring FGFR Alterations	Fase Fase 2	Date Added 2019-09-19	Ubicación Arizona, United States Georgia, United States Minnesota, United States North Carolina, United States Tennessee, United States Wisconsin, United States	Prior IO Allowed No	CRC-directed Sí	Status Activo, no recluta	Drogas Pemigatinib	Etiquetas MSS/ MMRp
NCT ID NCT04014530	TitlePembrolizumab With Ataluren in Patients With Metastatic pMMR and dMMR Colorectal Carcinoma or Metastatic dMMR Endometrial Carcinoma: the ATAPEMBRO Study	Fase Fase 1	Date Added 2019-07-10	Ubicación Países Bajos	Prior IO Allowed No	CRC-directed Sí	Status Reclutamiento	Drogas Ataluren + Pembrolizumab, Keytruda	Etiquetas MSS/ MMRp
NCT ID NCT03519412	TitlePembrolizumab en cáncer colorrectal metastásico competente en MMR preparado farmacológicamente para desencadenar el estado de hipermutación	Fase Fase 2	Date Added 2018-05-09	Ubicación Italia	Prior IO Allowed No	CRC-directed Sí	Status Activo, no recluta	Drogas pembrolizumab (treatment), temozolomide (induction),, Keytruda, Temodar	Etiquetas MSS/ MMRp

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