Clinical Trial Finder Search Results

About the Fight CRC Clinical Trial Finder

This Trial Finder is a one-stop place to find and learn more about high-impact clinical trials for colorectal cancer patients with advanced colon or rectal cancer. Originally created by the late Dr. Tom Marsilje as a curated spreadsheet of trials, the FightCRC’s Trial Finder is a resource to find research studies that are open in your geography, and for which you may be eligible. The current data is now for metastatic, stage IV patients with both MSS and MSI-H status. The list of trials here is sourced from the ClinicalTrials.gov website and curated with Comments and Helpful Links. The searches can be focused on immunotherapy-centered trials and narrowed to studies enrolling patients who already have received immunotherapies.

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The information contained in this website is not intended to recommend the self management of health problems, medical conditions or wellness. It is not intended to endorse or recommend any particular type of medical treatment, physician or treatment facility. Should any reader have any health care related questions, promptly call or consult your physician or healthcare provider. The information contained in this website should NOT be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Fight Colorectal Cancer disclaims any liability based on information provided in this website.

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NCT ID	Title	Fase	Date Added	Ubicación	Prior IO Allowed	CRC-directed	Status	Drogas	Etiquetas
NCT ID NCT05019534	TitleTolerability and Safety of Vemurafenib, Cetuximab Combined With Camrelizumab for BRAF V600E-mutated /MSS Metastatic Colorectal Cancer	Fase Fase 1	Date Added 2021-08-25	Ubicación China	Prior IO Allowed No	CRC-directed Sí	Status Reclutamiento	Drogas Camrelizumab, Cetuximab Injection [Erbitux], Vemurafenib Oral Tablet [Zelboraf]	Etiquetas MSS/ MMRp
NCT ID NCT04591431	TitleThe Rome Trial From Histology to Target: the Road to Personalize Target Therapy and Immunotherapy	Fase Fase 2	Date Added 2020-10-19	Ubicación Italia	Prior IO Allowed No	CRC-directed No	Status Activo, no recluta	Drogas Alectinib, Atezolizumab, Brigatinib, Cobimetinib, Entrectinib, Erlotinib, everolimus, Ipatasertib, Ipilimumab, Itacitinib, Lapatinib, Nivolumab, Oncology Drugs, palbociclib, Pemigatinib, Pertuzumab, Ponatinib, Trastuzumab, Trastuzumab emtansine, Vemurafenib, Vismogedib	Etiquetas MSS/ MMRp
NCT ID NCT03985891	TitleEficacia del JS001 combinado con quimioterapia en pacientes con cáncer de colon localmente avanzado	Fase Fase 1/Fase 2	Date Added 2019-06-14	Ubicación China	Prior IO Allowed Sí	CRC-directed Sí	Status Reclutamiento	Drogas Anti-PD-1 Monoclonal Antibody JS001, Chemotherapy	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT04984369	TitleThe Efficacy of HLX208 (BRAF V600E Inhibitor) With Cetuximab for Metastatic Colorectal Cancer (mCRC) With BRAF V600E Mutation After First-line Treatment	Fase Fase 2	Date Added 2021-07-30	Ubicación China	Prior IO Allowed Sí	CRC-directed Sí	Status Activo, no recluta	Drogas Cetuximab Injection [Erbitux], HLX208	Etiquetas MSS/ MMRp
NCT ID NCT02925234	TitleProtocolo de redescubrimiento de fármacos (ensayo DRUP)	Fase Fase 2	Date Added 2016-10-05	Ubicación Países Bajos	Prior IO Allowed Sí	CRC-directed No	Status Reclutamiento	Drogas Abemaciclib, afatinib, Alectinib, Alpelisib, Atezolizumab and Bevacizumab, Axitinib, Cabozantinib, Crizotinib, Dabrafenib, Dabrafenib and trametinib, Dacomitinib, durvalumab, Entrectinib, Erdafitinib, Erlotinib, Ipilimumab and nivolumab, Lenvatinib, lorlatinib, Nilotinib, Nivolumab, Olaparib, palbociclib, panitumumab, Pembrolizumab, Regorafenib, ribociclib, Rucaparib, Sunitinib, Talazoparib, Trametinib, Trastuzumab and Pertuzumab (combination treatment), Vemurafenib and Cobimetinib (combination treatment), Vismodegib	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT04535024	TitleThe Combination of Immunotherapy and Stereotactic Ablative Radiotherapy in MSS Oligometastatic Colorectal Cancer	Fase Fase 2	Date Added 2020-09-01	Ubicación China	Prior IO Allowed No	CRC-directed Sí	Status Reclutamiento	Drogas Sintilimab	Etiquetas MSS/ MMRp
NCT ID NCT04948034	TitleLa combinación de fruquintinib, tislelizumab y radioterapia ablativa estereotáctica en el cáncer colorrectal metastásico (RIFLE)	Fase Fase 2	Date Added 2021-07-01	Ubicación China	Prior IO Allowed No	CRC-directed Sí	Status Reclutamiento	Drogas Fruquintinib, Tislelizumab	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT02298959	TitleTesting the PD-1 Antibody, MK3475, Given With Ziv-aflibercept in Patients With Advanced Cancer	Fase Fase 1	Date Added 2014-11-24	Ubicación Florida, United States Maryland, United States Massachusetts, United States Canadá	Prior IO Allowed No	CRC-directed Sí	Status Activo, no recluta	Drogas Pembrolizumab, Ziv-Aflibercept, Keytruda, Zaltrap	Etiquetas MSS/ MMRp
NCT ID NCT03502733	TitleTesting the Combination of Copanlisib, Nivolumab and Ipilimumab in Patients With Advanced Cancer and Lymphoma	Fase Fase 1	Date Added 2018-04-19	Ubicación Maryland, United States Texas, United States	Prior IO Allowed Sí	CRC-directed No	Status Activo, no recluta	Drogas Copanlisib, Ipilimumab, Nivolumab, Aliqopa, Opdivo	Etiquetas MSS/ MMRp
NCT ID NCT05673148	TitlePrueba de la adición de la terapia ablativa total al tratamiento sistémico habitual para el cáncer colorrectal metastásico limitado, el estudio ERASur	Fase Fase 3	Date Added 2023-01-06	Ubicación Arizona, United States California, United States Delaware, United States District of Columbia, United States Florida, United States Georgia, United States Idaho, United States Illinois, United States Iowa, United States Kentucky, United States Maryland, United States Michigan, United States Minnesota, United States Mississippi, United States Missouri, United States Montana, United States Nebraska, United States Nevada, United States New Hampshire, United States New Jersey, United States New Mexico, United States New York, United States North Dakota, United States Ohio, United States Oklahoma, United States Pennsylvania, United States South Dakota, United States Tennessee, United States Texas, United States Utah, United States Washington, United States Wisconsin, United States	Prior IO Allowed No	CRC-directed Sí	Status Reclutamiento	Drogas Quimioterapia	Etiquetas MSS/ MMRp

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