Clinical Trial Finder Search Results

About the Fight CRC Clinical Trial Finder

This Trial Finder is a one-stop place to find and learn more about high-impact clinical trials for colorectal cancer patients with advanced colon or rectal cancer. Originally created by the late Dr. Tom Marsilje as a curated spreadsheet of trials, the FightCRC’s Trial Finder is a resource to find research studies that are open in your geography, and for which you may be eligible. The current data is now for metastatic, stage IV patients with both MSS and MSI-H status. The list of trials here is sourced from the ClinicalTrials.gov website and curated with Comments and Helpful Links. The searches can be focused on immunotherapy-centered trials and narrowed to studies enrolling patients who already have received immunotherapies.

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The information contained in this website is not intended to recommend the self management of health problems, medical conditions or wellness. It is not intended to endorse or recommend any particular type of medical treatment, physician or treatment facility. Should any reader have any health care related questions, promptly call or consult your physician or healthcare provider. The information contained in this website should NOT be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Fight Colorectal Cancer disclaims any liability based on information provided in this website.

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NCT ID	Title	Fase	Date Added	Ubicación	Prior IO Allowed	CRC-directed	Status	Drogas	Etiquetas
NCT ID NCT04111172	TitleUna vacuna (Ad5.F35-hGCC-PADRE) para el tratamiento del adenocarcinoma gastrointestinal	Fase Fase 2	Date Added 2019-10-01	Ubicación Pennsylvania, United States	Prior IO Allowed Sí	CRC-directed Sí	Status Activo, no recluta	Drogas Adenovirus 5/F35-Human Guanylyl Cyclase C-PADRE	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03547999	TitleA Trial of Perioperative CV301 Vaccination in Combination With Nivolumab and Systemic Chemotherapy for Metastatic CRC	Fase Fase 2	Date Added 2018-06-06	Ubicación California, United States Florida, United States Kansas, United States New Jersey, United States Ohio, United States Oregon, United States	Prior IO Allowed Sí	CRC-directed Sí	Status Activo, no recluta	Drogas FPV-CV301, mFOLFOX6, MVA-BN-CV301, Nivolumab	Etiquetas MSS/ MMRp
NCT ID NCT03673787	TitleUn ensayo de ipatasertib en combinación con atezolizumab	Fase Fase 1	Date Added 2018-09-17	Ubicación Reino Unido	Prior IO Allowed Sí	CRC-directed No	Status Reclutamiento	Drogas Atezolizumab, Ipatasertib	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03990233	TitleEnsayo de BI 765063 en monoterapia y en combinación con BI 754091 en pacientes con tumores sólidos avanzados.	Fase Fase 1	Date Added 2019-06-18	Ubicación Bélgica Francia	Prior IO Allowed Sí	CRC-directed No	Status Activo, no recluta	Drogas BI 754091, BI 765063	Etiquetas MSS/ MMRp
NCT ID NCT04973163	TitleEstudio para probar diferentes dosis de BI 1823911 solo y combinado con otros medicamentos en personas con diferentes tipos de cáncer avanzado con mutación KRAS.	Fase Fase 1	Date Added 2021-07-22	Ubicación Texas, United States Bélgica España Reino Unido	Prior IO Allowed No	CRC-directed No	Status Activo, no recluta	Drogas BI 1701963, BI 1823911, Midazolam	Etiquetas MSS/ MMRp
NCT ID NCT04111458	TitleA Study to Test Different Doses of BI 1701963 Alone and Combined With Trametinib in Patients With Different Types of Advanced Cancer (Solid Tumours With KRAS Mutation)	Fase Fase 1	Date Added 2019-10-01	Ubicación Massachusetts, United States North Carolina, United States Tennessee, United States Texas, United States Alemania Países Bajos	Prior IO Allowed Sí	CRC-directed No	Status Activo, no recluta	Drogas BI 1701963, Trametinib	Etiquetas MSS/ MMRp
NCT ID NCT05487235	TitleA Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors	Fase Fase 1	Date Added 2022-08-04	Ubicación Argentina Australia Brasil Canadá Corea, República de Nueva Zelanda	Prior IO Allowed Sí	CRC-directed No	Status Activo, no recluta	Drogas Atezolizumab, GDC-1971, Omeprazole	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03530397	TitleUn estudio para evaluar MEDI5752 en sujetos con tumores sólidos avanzados	Fase Fase 1	Date Added 2018-05-21	Ubicación Michigan, United States New York, United States North Carolina, United States Rhode Island, United States Tennessee, United States Virginia, United States Australia Francia Italia Corea, República de Países Bajos Portugal España Taiwán	Prior IO Allowed Sí	CRC-directed No	Status Activo, no recluta	Drogas Carboplatin, MEDI5752, Pembrolizumab, Pemetrexed, Alimta, Imfinzi, Keytruda, Paraplatin	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT05879822	TitleEstudio para evaluar INCB099280 en participantes con tumores sólidos seleccionados que no han recibido ningún inhibidor de los puntos de control inmunitarios.	Fase Fase 2	Date Added 2023-05-30	Ubicación Brasil China Georgia Greece Hungary Nueva Zelanda Romania Sudáfrica Turkey	Prior IO Allowed No	CRC-directed No	Status Activo, no recluta	Drogas INCB099280	Etiquetas MSI-H/ MMRd
NCT ID NCT06322693	TitleA Study of TSR-022 in Participants With Advanced Solid Tumors (AMBER)	Fase Fase 1	Date Added 2024-03-21	Ubicación Arizona, United States California, United States Colorado, United States Connecticut, United States District of Columbia, United States Florida, United States Georgia, United States Illinois, United States Iowa, United States Kansas, United States Kentucky, United States Maryland, United States Massachusetts, United States Michigan, United States Minnesota, United States New Jersey, United States New York, United States Ohio, United States Oregon, United States Pennsylvania, United States South Carolina, United States Tennessee, United States Texas, United States Virginia, United States Washington, United States Wisconsin, United States Corea, República de España	Prior IO Allowed No	CRC-directed Sí	Status Reclutamiento	Drogas Carboplatin, cisplatin, Docetaxel, Nivolumab, Pemetrexed, TSR-022, TSR-033, TSR-042	Etiquetas MSI-H/ MMRd, MSS/ MMRp

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