Clinical Trial Finder Search Results

About the Fight CRC Clinical Trial Finder

This Trial Finder is a one-stop place to find and learn more about high-impact clinical trials for colorectal cancer patients with advanced colon or rectal cancer. Originally created by the late Dr. Tom Marsilje as a curated spreadsheet of trials, the FightCRC’s Trial Finder is a resource to find research studies that are open in your geography, and for which you may be eligible. The current data is now for metastatic, stage IV patients with both MSS and MSI-H status. The list of trials here is sourced from the ClinicalTrials.gov website and curated with Comments and Helpful Links. The searches can be focused on immunotherapy-centered trials and narrowed to studies enrolling patients who already have received immunotherapies.

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The information contained in this website is not intended to recommend the self management of health problems, medical conditions or wellness. It is not intended to endorse or recommend any particular type of medical treatment, physician or treatment facility. Should any reader have any health care related questions, promptly call or consult your physician or healthcare provider. The information contained in this website should NOT be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Fight Colorectal Cancer disclaims any liability based on information provided in this website.

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NCT ID	Title	Fase	Date Added	Ubicación	Prior IO Allowed	CRC-directed	Status	Drogas	Etiquetas
NCT ID NCT06493760	TitleA Phase 2 Study of SSGJ-707 in Metastatic Colorectal Cancer Patients	Fase Fase 2	Date Added 2024-07-10	Ubicación China	Prior IO Allowed No	CRC-directed Sí	Status Reclutamiento	Drogas	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03600883	TitleA Phase 1/2, Study Evaluating the Safety, Tolerability, PK, and Efficacy of Sotorasib (AMG 510) in Subjects With Solid Tumors With a Specific KRAS Mutation (CodeBreaK 100)	Fase Phase 1, Phase 2	Date Added 2018-07-26	Ubicación California, United States Colorado, United States Connecticut, United States Delaware, United States Florida, United States Georgia, United States Indiana, United States Maryland, United States Massachusetts, United States Michigan, United States Missouri, United States New York, United States North Carolina, United States Ohio, United States Pennsylvania, United States South Carolina, United States Tennessee, United States Texas, United States Utah, United States Virginia, United States Washington, United States Australia Austria Bélgica Brasil Canadá Francia Alemania Greece Hungary Japón Corea, República de Portugal Romania España Suiza	Prior IO Allowed Sí	CRC-directed No	Status Activo, no recluta	Drogas Anti PD-1/L1, Midazolam, Sotorasib	Etiquetas MSS/ MMRp
NCT ID NCT06055439	TitleEstudio de fase 1/2 para evaluar CHM-2101, una terapia autóloga con células T receptoras de antígeno quimérico (CAR) de cadherina 17.	Fase Phase 1, Phase 2	Date Added 2023-09-26	Ubicación Georgia, United States Illinois, United States Pennsylvania, United States Tennessee, United States	Prior IO Allowed Sí	CRC-directed Sí	Status Reclutamiento	Drogas	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT06011772	TitleA Phase 0 Study of EGF-Depleting Therapy CIMAvax-EGF in Combination With Standard Therapy for RAS- and BRAF Wild-Type Metastatic Colorectal Cancer	Fase Fase inicial 1	Date Added 2023-08-25	Ubicación New York, United States	Prior IO Allowed Sí	CRC-directed Sí	Status Suspendido	Drogas fluorouracil, Irinotecan, Leucovorin, oxaliplatin	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT06412198	TitleA Multicenter Phase 1b/2 Study of Adagrasib, Cetuximab, and Cemiplimab for Metastatic Colorectal Cancer Harboring KRAS G12C Mutations	Fase Phase 1, Phase 2	Date Added 2024-05-14	Ubicación Massachusetts, United States Texas, United States	Prior IO Allowed No	CRC-directed Sí	Status Reclutamiento	Drogas Adagrasib, cemiplimab, cetuximab	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT05865535	TitleA Dose Escalation Study of AV-380 in Metastatic Cancer Patients With Cachexia	Fase Fase 1	Date Added 2023-05-19	Ubicación California, United States Florida, United States Georgia, United States Nebraska, United States New York, United States Oregon, United States South Carolina, United States Tennessee, United States Texas, United States	Prior IO Allowed No	CRC-directed No	Status Reclutamiento	Drogas	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT06010901	TitleA Clinical Study of TQB2618 Injection Monotherapy and Combination Regimen (With Penpulimab Injection ±Anlotinib Hydrochloride Capsules) in the Four or Later Lines of Treatment of Advanced Colorectal Cancer.	Fase Fase 1	Date Added 2023-08-25	Ubicación China	Prior IO Allowed Sí	CRC-directed Sí	Status Reclutamiento	Drogas Anlotinib hydrochloride capsules, Penpulimab Injection, TQB2618 injection	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT05973487	TitleA Basket Study of Customized Autologous TCR-T Cell Therapies in Patients With Locally Advanced (Unresectable) or Metastatic Solid Tumors	Fase Fase 1	Date Added 2023-08-03	Ubicación Arizona, United States California, United States Connecticut, United States Florida, United States Illinois, United States Kentucky, United States Michigan, United States Minnesota, United States New York, United States North Carolina, United States Ohio, United States Oklahoma, United States Oregon, United States Pennsylvania, United States Tennessee, United States Texas, United States	Prior IO Allowed Sí	CRC-directed Sí	Status Reclutamiento	Drogas	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT06856837	Title– IKF/AIO-QUINTIS – Evaluating Fruquintinib in Combination With Tislelizumab in Microsatellite Stable / Proficient Mismatch Repair (MSS/pMMR) Metastatic Colorectal Cancer Without Active Liver Metastases	Fase Fase 2	Date Added 2025-03-04	Ubicación Austria Alemania	Prior IO Allowed No	CRC-directed Sí	Status Aún no se ha contratado	Drogas	Etiquetas MSS/ MMRp

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