Clinical Trial Finder Search Results

About the Fight CRC Clinical Trial Finder

This Trial Finder is a one-stop place to find and learn more about high-impact clinical trials for colorectal cancer patients with advanced colon or rectal cancer. Originally created by the late Dr. Tom Marsilje as a curated spreadsheet of trials, the FightCRC’s Trial Finder is a resource to find research studies that are open in your geography, and for which you may be eligible. The current data is now for metastatic, stage IV patients with both MSS and MSI-H status. The list of trials here is sourced from the ClinicalTrials.gov website and curated with Comments and Helpful Links. The searches can be focused on immunotherapy-centered trials and narrowed to studies enrolling patients who already have received immunotherapies.

Medical Disclaimer

The information contained in this website is not intended to recommend the self management of health problems, medical conditions or wellness. It is not intended to endorse or recommend any particular type of medical treatment, physician or treatment facility. Should any reader have any health care related questions, promptly call or consult your physician or healthcare provider. The information contained in this website should NOT be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Fight Colorectal Cancer disclaims any liability based on information provided in this website.

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NCT ID	Title	Phase	Date Added	Location	Prior IO Allowed	CRC-directed	Status	Drugs	Tags
NCT ID NCT04895709	TitleA Study of BMS-986340 as Monotherapy and in Combination With Nivolumab in Participants With Advanced Solid Tumors	Phase Phase 1, Phase 2	Date Added 2021-05-20	Location California, United States Iowa, United States New Jersey, United States New York, United States Oregon, United States Tennessee, United States Texas, United States Australia Canada China Germany Israel Italy Japan Spain	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs BMS-936558-01, BMS-986340	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT04653480	TitleSurufatinib, Toripalimab and Chemotherapy in Second-line MT and MSS CRC	Phase Phase 2	Date Added 2020-12-04	Location China	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs Chemotherapy, Surufatinib, Toripalimab	Tags MSS/ MMRp
NCT ID NCT03925662	TitleMebendazole as Adjuvant Treatment for Colon Cancer	Phase Phase 3	Date Added 2019-04-24	Location Egypt	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs Folfox with avastin, Mebendazole	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT04948034	TitleThe Combination of Fruquintinib, Tislelizumab and Stereotactic Ablative Radiotherapy in Metastatic Colorectal Cancer(RIFLE)	Phase Phase 2	Date Added 2021-07-01	Location China	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs Fruquintinib, Tislelizumab	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT02856425	TitleTrial Of Pembrolizumab And Nintedanib	Phase Phase 1	Date Added 2016-08-04	Location France	Prior IO Allowed No	CRC-directed No	Status Recruiting	Drugs Nintedanib, Pembrolizumab, Keytruda, Ofev, Vargatef	Tags MSS/ MMRp
NCT ID NCT04659382	TitleStudy to Evaluate Efficacy and Safety of Selective Internal Radiation Therapy Plus Xelox, Bevacizumab and Atezolizumab (Immune Chekpoint Inhibitor) in Patients With Liver-dominant Metastatic Colorectal Cancer	Phase Phase 2	Date Added 2020-12-09	Location France	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs Atezolizumab, Bevacizumab, TheraSphere, XELOX	Tags MSS/ MMRp
NCT ID NCT05213195	TitleNKG2D CAR-NK Cell Therapy in Patients With Refractory Metastatic Colorectal Cancer	Phase Phase 1	Date Added 2022-01-28	Location China	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs NKG2D CAR-NK	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03950154	TitleStudy of Chemotherapy Combination With Autologous Cell Immunotherapy in the Recurrent and Metastatic Colorectal Cancer	Phase Phase 3	Date Added 2019-05-15	Location China	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs Bevacizumab Injection [Avastin], capecitabine, oxaliplatin, PD1-T cells	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03190941	TitleAdministering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients	Phase Phase 1, Phase 2	Date Added 2017-06-19	Location Maryland, United States	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs Anti-KRAS G12V mTCR PBL, Cyclophosphamide, Fludarabine, High-dose Aldesleukin	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03935893	TitleAdoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers	Phase Phase 2	Date Added 2019-05-02	Location Pennsylvania, United States	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs Fludarabine + Cyclophosphamide combination, Tumor Infiltrating Lymphocytes (TIL)	Tags MSI-H/ MMRd, MSS/ MMRp

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