Clinical Trial Finder Search Results

About the Fight CRC Clinical Trial Finder

This Trial Finder is a one-stop place to find and learn more about high-impact clinical trials for colorectal cancer patients with advanced colon or rectal cancer. Originally created by the late Dr. Tom Marsilje as a curated spreadsheet of trials, the FightCRC’s Trial Finder is a resource to find research studies that are open in your geography, and for which you may be eligible. The current data is now for metastatic, stage IV patients with both MSS and MSI-H status. The list of trials here is sourced from the ClinicalTrials.gov website and curated with Comments and Helpful Links. The searches can be focused on immunotherapy-centered trials and narrowed to studies enrolling patients who already have received immunotherapies.

Medical Disclaimer

The information contained in this website is not intended to recommend the self management of health problems, medical conditions or wellness. It is not intended to endorse or recommend any particular type of medical treatment, physician or treatment facility. Should any reader have any health care related questions, promptly call or consult your physician or healthcare provider. The information contained in this website should NOT be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Fight Colorectal Cancer disclaims any liability based on information provided in this website.

Location

MS status

Recruitment Status

Phase

Drugs

Prior Immunotherapy Allowed

NCT ID

Title key word search

Date Trial Added

From To

View:

Compact Expanded

PDF Excel CSV

NCT ID	Title	Phase	Date Added	Location	Prior IO Allowed	CRC-directed	Status	Drugs	Tags
NCT ID NCT05319314	TitleGCC19CART for Patients With Metastatic Colorectal Cancer	Phase Phase 1	Date Added 2022-04-08	Location California, United States Colorado, United States Massachusetts, United States Michigan, United States Texas, United States	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs GCC19CART	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT05785325	TitleRC48-ADC Combined With Bevacizumab in HER2-positive Advanced Colorectal Cancer	Phase Phase 2	Date Added 2023-03-27	Location China	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs RC48-ADC plus Bevacizumab	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT05784688	TitleStudy of TU2218 in Combination With Pembrolizumab in Patients With Advanced Solid Tumors	Phase Phase 1, Phase 2	Date Added 2023-03-27	Location Texas, United States Washington, United States Korea, Republic of	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs TU2218 + Pembrolizumab	Tags MSS/ MMRp
NCT ID NCT05798533	TitleNeo-T in Treating Patients With Advanced Solid Tumors(GI-NeoT-03)	Phase Phase 1	Date Added 2023-04-04	Location China	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs Cyclophosphamide, Fludarabine, Interleukin-2	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT00001823	TitleEvaluation for NCI Surgery Branch Immunotherapy Clinical Research Protocols	Phase	Date Added 1999-11-04	Location Maryland, United States	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT05382741	TitleAdjuvant Durvalumab Plus Regorafenib vs Untreated Control in Stage IV Colorectal Cancer Patients With no Evidence of Disease (NED): VIVA Trial	Phase Phase 2	Date Added 2022-05-19	Location Italy	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs Durvalumab Injection for intravenous use 500 mg vial solution for infusion, Regorafenib 30 mg capsules, Imfinzi, Stivarga	Tags MSS/ MMRp
NCT ID NCT05838768	TitleStudy of HRO761 Alone or in Combination in Cancer Patients With Specific DNA Alterations Called Microsatellite Instability or Mismatch Repair Deficiency.	Phase Phase 1	Date Added 2023-05-03	Location California, United States Massachusetts, United States New York, United States Texas, United States Belgium China France Germany Israel Italy Japan Norway Singapore South Korea Spain Sweden Taiwan United Kingdom	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs HRO761, Irinotecan	Tags MSI-H/ MMRd
NCT ID NCT05426005	TitleCadonilimab for PD-1/PD-L1 Blockade-refractory, MSI-H/dMMR, Advanced Colorectal Cancer	Phase Phase 1, Phase 2	Date Added 2022-06-21	Location China	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs Cadonilimab	Tags MSI-H/ MMRd
NCT ID NCT03667170	TitleKN035 for dMMR/MSI-H Advanced Solid Tumors	Phase Phase 2	Date Added 2018-09-12	Location China	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs	Tags MSI-H/ MMRd
NCT ID NCT05239741	TitleStudy of Pembrolizumab (MK-3475) Versus Chemotherapy in Chinese Participants With Stage IV Colorectal Cancer (MK-3475-C66)	Phase Phase 3	Date Added 2022-02-15	Location China	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs 5-Fluorouracil, Irinotecan, Leucovorin, oxaliplatin	Tags MSI-H/ MMRd

Showing 111 to 120 of 299 entries