Clinical Trial Finder Search Results

About the Fight CRC Clinical Trial Finder

This Trial Finder is a one-stop place to find and learn more about high-impact clinical trials for colorectal cancer patients with advanced colon or rectal cancer. Originally created by the late Dr. Tom Marsilje as a curated spreadsheet of trials, the FightCRC’s Trial Finder is a resource to find research studies that are open in your geography, and for which you may be eligible. The current data is now for metastatic, stage IV patients with both MSS and MSI-H status. The list of trials here is sourced from the ClinicalTrials.gov website and curated with Comments and Helpful Links. The searches can be focused on immunotherapy-centered trials and narrowed to studies enrolling patients who already have received immunotherapies.

Medical Disclaimer

The information contained in this website is not intended to recommend the self management of health problems, medical conditions or wellness. It is not intended to endorse or recommend any particular type of medical treatment, physician or treatment facility. Should any reader have any health care related questions, promptly call or consult your physician or healthcare provider. The information contained in this website should NOT be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Fight Colorectal Cancer disclaims any liability based on information provided in this website.

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NCT ID	Title	Phase	Date Added	Location	Prior IO Allowed	CRC-directed	Status	Drugs	Tags
NCT ID NCT05308446	TitleTesting the Addition of Nivolumab to Standard Treatment for Patients With Metastatic or Unresectable Colorectal Cancer That Have a BRAF Mutation	Phase Phase 2	Date Added 2022-04-04	Location Arizona, United States California, United States Colorado, United States Georgia, United States Hawaii, United States Idaho, United States Illinois, United States Indiana, United States Iowa, United States Louisiana, United States Michigan, United States Minnesota, United States Missouri, United States Montana, United States New Hampshire, United States New Jersey, United States New York, United States North Carolina, United States Ohio, United States Oklahoma, United States Oregon, United States Pennsylvania, United States Rhode Island, United States South Carolina, United States Tennessee, United States Texas, United States Utah, United States Vermont, United States Washington, United States West Virginia, United States Wisconsin, United States Puerto Rico	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs cetuximab, encorafenib, Nivolumab, Braftovi, Erbitux, Opdivo	Tags MSS/ MMRp
NCT ID NCT03096093	TitleInvestigation of a Therapeutic Vaccine (ACIT-1) in Cancer	Phase Phase 1, Phase 2	Date Added 2017-03-30	Location United Kingdom	Prior IO Allowed Yes	CRC-directed No	Status Active, not recruiting	Drugs ACIT-1	Tags MSS/ MMRp
NCT ID NCT03030378	TitlePembrolizumab and Recombinant Interleukin-12 in Treating Patients With Solid Tumors	Phase Phase 1	Date Added 2017-01-25	Location California, United States Colorado, United States Connecticut, United States Florida, United States Georgia, United States Iowa, United States Maryland, United States Massachusetts, United States Missouri, United States New Jersey, United States North Carolina, United States Ohio, United States Pennsylvania, United States Texas, United States Virginia, United States	Prior IO Allowed No	CRC-directed No	Status Active, not recruiting	Drugs Edodekin alfa, Pembrolizumab	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03994601	TitleAn Investigational Immunotherapy Study of BMS-986288 Alone and in Combination With Nivolumab in Advanced Solid Cancers	Phase Phase 1	Date Added 2019-06-21	Location California, United States Colorado, United States Maryland, United States Missouri, United States New Jersey, United States Argentina Canada Chile France Italy Spain	Prior IO Allowed Yes	CRC-directed No	Status Active, not recruiting	Drugs BMS-986288, Nivolumab, Opdivo	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03795311	TitleEvaluation of the Efficacy and the Safety of FOLFIRINOX3 Bevacizumab Treatment in Patients With Colorectal Cancer (FOLFIRINOX 3)	Phase Phase 1, Phase 2	Date Added 2019-01-07	Location France	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs FOLFIRINOX Bevacizumab	Tags MSS/ MMRp
NCT ID NCT03983993	TitleNiraparib and Panitumumab in Patients With Advanced or Metastatic Colorectal Cancer	Phase Phase 2	Date Added 2019-06-12	Location Georgia, United States	Prior IO Allowed Yes	CRC-directed Yes	Status Active, not recruiting	Drugs Niraparib, panitumumab, Vectibix, Zejula	Tags MSS/ MMRp
NCT ID NCT04046445	TitlePhase 1b Study to Evaluate ATP128, VSV-GP128 and BI 754091, in Patients With Stage IV Colorectal Cancer	Phase Phase 1	Date Added 2019-08-06	Location Arizona, United States California, United States Colorado, United States New York, United States North Carolina, United States Texas, United States Belgium Germany Switzerland	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs ATP128, BI 754091, VSV-GP128	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03867799	TitleiSCORE: Immunotherapy Sequencing in COlon and REctal Cancer	Phase Phase 2	Date Added 2019-03-08	Location United Kingdom	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs Nivolumab	Tags MSS/ MMRp
NCT ID NCT04017650	TitleEncorafenib, Cetuximab, and Nivolumab in Treating Patients With Microsatellite Stable, BRAFV600E Mutated Unresectable or Metastatic Colorectal Cancer	Phase Phase 1, Phase 2	Date Added 2019-07-12	Location Texas, United States	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs cetuximab, encorafenib, Nivolumab	Tags MSS/ MMRp
NCT ID NCT05167409	TitleA Study of ALX148 With Cetuximab and Pembrolizumab for Refractory Microsatellite Stable Metastatic Colorectal Cancer	Phase Phase 2	Date Added 2021-12-22	Location Arizona, United States Colorado, United States New Jersey, United States Virginia, United States	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs ALX148, cetuximab, Evorpacept (ALX148), Pembrolizumab, Erbitux, Keytruda	Tags MSS/ MMRp

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