Clinical Trial Finder Search Results

About the Fight CRC Clinical Trial Finder

This Trial Finder is a one-stop place to find and learn more about high-impact clinical trials for colorectal cancer patients with advanced colon or rectal cancer. Originally created by the late Dr. Tom Marsilje as a curated spreadsheet of trials, the FightCRC’s Trial Finder is a resource to find research studies that are open in your geography, and for which you may be eligible. The current data is now for metastatic, stage IV patients with both MSS and MSI-H status. The list of trials here is sourced from the ClinicalTrials.gov website and curated with Comments and Helpful Links. The searches can be focused on immunotherapy-centered trials and narrowed to studies enrolling patients who already have received immunotherapies.

Medical Disclaimer

The information contained in this website is not intended to recommend the self management of health problems, medical conditions or wellness. It is not intended to endorse or recommend any particular type of medical treatment, physician or treatment facility. Should any reader have any health care related questions, promptly call or consult your physician or healthcare provider. The information contained in this website should NOT be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Fight Colorectal Cancer disclaims any liability based on information provided in this website.

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NCT ID	Title	Phase	Date Added	Location	Prior IO Allowed	CRC-directed	Status	Drugs	Tags
NCT ID NCT03599765	TitleSystemic Therapy With or Without Local Consolidative Therapy in Treating Patients With Oligometastatic Solid Tumor	Phase Phase 2	Date Added 2018-07-26	Location Arizona, United States Arkansas, United States Hawaii, United States Michigan, United States New Jersey, United States Ohio, United States Texas, United States	Prior IO Allowed Yes	CRC-directed No	Status Active, not recruiting	Drugs	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03568058	TitlePersonalized Immunotherapy in Adults With Advanced Cancers Immunotherapy in Adults With Advanced Cancers	Phase Phase 1	Date Added 2018-06-26	Location California, United States	Prior IO Allowed Yes	CRC-directed No	Status Active, not recruiting	Drugs Pembrolizumab, personalized vaccine, Keytruda	Tags MSS/ MMRp
NCT ID NCT03844750	TitlePembrolizumab After Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver and Who Are Undergoing Liver Surgery	Phase Phase 2	Date Added 2019-02-18	Location California, United States	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs Pembrolizumab, Vactosertib, Keytruda	Tags MSS/ MMRp
NCT ID NCT05243862	TitleSafety and Activity of PolyPEPI1018 Plus Atezolizumab in Colorectal Cancer.	Phase Phase 2	Date Added 2022-02-17	Location Arizona, United States Florida, United States Minnesota, United States	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs Atezolizumab, PolyPEPI1018, Tecentriq	Tags MSS/ MMRp
NCT ID NCT02988960	TitleA Study of ABBV-927 and ABBV-181, an Immunotherapy, in Participants With Advanced Solid Tumors	Phase Phase 1	Date Added 2016-12-12	Location California, United States Illinois, United States Massachusetts, United States North Carolina, United States Tennessee, United States Texas, United States Virginia, United States Australia Canada France Japan Korea, Republic of Spain	Prior IO Allowed Yes	CRC-directed No	Status Active, not recruiting	Drugs ABBV-181, ABBV-927, Opdivo	Tags MSS/ MMRp
NCT ID NCT04426669	TitleA Study of Metastatic Gastrointestinal Cancers Treated With Tumor Infiltrating Lymphocytes in Which the Gene Encoding the Intracellular Immune Checkpoint CISH Is Inhibited Using CRISPR Genetic Engineering	Phase Phase 1	Date Added 2020-06-11	Location Minnesota, United States	Prior IO Allowed Yes	CRC-directed Yes	Status Active, not recruiting	Drugs Aldesleukin, Cyclophosphamide, Fludarabine, Tumor Infiltrating Lymphocytes (TIL)	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT04111172	TitleA Vaccine (Ad5.F35-hGCC-PADRE) for the Treatment of Gastrointestinal Adenocarcinoma	Phase Phase 2	Date Added 2019-10-01	Location Pennsylvania, United States	Prior IO Allowed Yes	CRC-directed Yes	Status Active, not recruiting	Drugs Adenovirus 5/F35-Human Guanylyl Cyclase C-PADRE	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT04117087	TitlePooled Mutant KRAS-Targeted Long Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Resected MMR-p Colorectal and Pancreatic Cancer	Phase Phase 1	Date Added 2019-10-07	Location Maryland, United States	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs Ipilimumab, Nivolumab, Opdivo, Yervoy	Tags MSS/ MMRp
NCT ID NCT05722327	TitlePhase I Trial of Adagrasib (MRTX849) in Combination With Cetuximab and Irinotecan in Patients With Colorectal Cancer	Phase Phase 1	Date Added 2023-02-10	Location Texas, United States	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs cetuximab, Irinotecan, MRTX849	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT05726864	TitleA Study of ELI-002 7P in Subjects With KRAS/NRAS Mutated Solid Tumors	Phase Phase 1, Phase 2	Date Added 2023-02-14	Location Arizona, United States California, United States Colorado, United States Florida, United States Georgia, United States Iowa, United States Louisiana, United States Massachusetts, United States Michigan, United States Minnesota, United States New York, United States Pennsylvania, United States Tennessee, United States Texas, United States Wisconsin, United States	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs ELI-002 7P	Tags MSI-H/ MMRd, MSS/ MMRp

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