Clinical Trial Finder Search Results

About the Fight CRC Clinical Trial Finder

This Trial Finder is a one-stop place to find and learn more about high-impact clinical trials for colorectal cancer patients with advanced colon or rectal cancer. Originally created by the late Dr. Tom Marsilje as a curated spreadsheet of trials, the FightCRC’s Trial Finder is a resource to find research studies that are open in your geography, and for which you may be eligible. The current data is now for metastatic, stage IV patients with both MSS and MSI-H status. The list of trials here is sourced from the ClinicalTrials.gov website and curated with Comments and Helpful Links. The searches can be focused on immunotherapy-centered trials and narrowed to studies enrolling patients who already have received immunotherapies.

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The information contained in this website is not intended to recommend the self management of health problems, medical conditions or wellness. It is not intended to endorse or recommend any particular type of medical treatment, physician or treatment facility. Should any reader have any health care related questions, promptly call or consult your physician or healthcare provider. The information contained in this website should NOT be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Fight Colorectal Cancer disclaims any liability based on information provided in this website.

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NCT ID	Title	Fase	Date Added	Ubicación	Prior IO Allowed	CRC-directed	Status	Drogas	Etiquetas
NCT ID NCT03940820	TitleInvestigación clínica de células CAR-NK específicas de ROBO1 en pacientes con tumores sólidos	Fase Fase 1/Fase 2	Date Added 2019-05-07	Ubicación China	Prior IO Allowed No	CRC-directed No	Status Reclutamiento	Drogas Células CAR-NK ROBO1	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03795311	TitleEvaluación de la eficacia y la seguridad del tratamiento con FOLFIRINOX3 Bevacizumab en pacientes con cáncer colorrectal (FOLFIRINOX 3)	Fase Phase 1, Phase 2	Date Added 2019-01-07	Ubicación Francia	Prior IO Allowed No	CRC-directed Sí	Status Activo, no recluta	Drogas FOLFIRINOX Bevacizumab	Etiquetas MSS/ MMRp
NCT ID NCT03874897	TitleChimeric Antigen Receptor T Cells Targeting claudin18.2 in Solid Tumors.	Fase Fase 1	Date Added 2019-03-14	Ubicación China	Prior IO Allowed No	CRC-directed No	Status Reclutamiento	Drogas CAR-CLDN18.2 T-Cells, Chemotherapy, PD-1 Monoclonal Antibody	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT04046445	TitleEstudio de fase 1b para evaluar ATP128, VSV-GP128 y BI 754091, en pacientes con cáncer colorrectal en estadio IV	Fase Fase 1	Date Added 2019-08-06	Ubicación Arizona, United States California, United States Colorado, United States New York, United States North Carolina, United States Texas, United States Bélgica Alemania Suiza	Prior IO Allowed No	CRC-directed Sí	Status Activo, no recluta	Drogas ATP128, BI 754091, VSV-GP128	Etiquetas MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03867799	TitleiSCORE: Immunotherapy Sequencing in COlon and REctal Cancer	Fase Fase 2	Date Added 2019-03-08	Ubicación Reino Unido	Prior IO Allowed No	CRC-directed Sí	Status Activo, no recluta	Drogas Nivolumab	Etiquetas MSS/ MMRp
NCT ID NCT02499328	TitleStudy to Assess MEDI4736 With Either AZD9150 or AZD5069 in Advanced Solid Tumors & Relapsed Metastatic Squamous Cell Carcinoma of Head & Neck	Fase Phase 1, Phase 2	Date Added 2015-07-16	Ubicación Alabama, United States California, United States Colorado, United States Florida, United States Indiana, United States Massachusetts, United States Michigan, United States Montana, United States New Jersey, United States Ohio, United States Texas, United States Virginia, United States Washington, United States Bélgica Alemania Italia España Reino Unido	Prior IO Allowed No	CRC-directed No	Status Activo, no recluta	Drogas AZD5069, AZD9150, MEDI4736, tremelimumab (treme)	Etiquetas MSS/ MMRp
NCT ID NCT04017650	TitleEncorafenib, Cetuximab, and Nivolumab in Treating Patients With Microsatellite Stable, BRAFV600E Mutated Unresectable or Metastatic Colorectal Cancer	Fase Phase 1, Phase 2	Date Added 2019-07-12	Ubicación Texas, United States	Prior IO Allowed No	CRC-directed Sí	Status Activo, no recluta	Drogas cetuximab, encorafenib, Nivolumab	Etiquetas MSS/ MMRp
NCT ID NCT03711058	TitleStudy of PI3Kinase Inhibition (Copanlisib) and Anti-PD-1 Antibody Nivolumab in Relapsed/Refractory Solid Tumors With Expansions in Mismatch-repair Proficient (MSS) Colorectal Cancer	Fase Phase 1, Phase 2	Date Added 2018-10-18	Ubicación Maryland, United States	Prior IO Allowed No	CRC-directed Sí	Status Activo, no recluta	Drogas Copanlisib, Nivolumab	Etiquetas MSS/ MMRp
NCT ID NCT05167409	TitleA Study of ALX148 With Cetuximab and Pembrolizumab for Refractory Microsatellite Stable Metastatic Colorectal Cancer	Fase Fase 2	Date Added 2021-12-22	Ubicación Arizona, United States Colorado, United States New Jersey, United States Virginia, United States	Prior IO Allowed No	CRC-directed Sí	Status Activo, no recluta	Drogas ALX148, cetuximab, Evorpacept (ALX148), Pembrolizumab, Erbitux, Keytruda	Etiquetas MSS/ MMRp
NCT ID NCT03727763	TitleCetuximab y vemurafenib más FOLFIRI para el cáncer colorrectal avanzado con mutación BRAF V600E (IMPROVEMENT)	Fase Fase 2	Date Added 2018-11-01	Ubicación China	Prior IO Allowed No	CRC-directed Sí	Status Reclutamiento	Drogas cetuximab, Vemurafenib	Etiquetas MSI-H/ MMRd, MSS/ MMRp

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