Stool tests2025-01-14T10:44:35+00:00

Stool Tests for Colorectal Cancer

Innovations in science and technology have created tests for colon cancer screening that you can do at home. Several of these tests
have received FDA approval.

Stool Tests for Colorectal Cancer

Innovations in science and technology have created tests for colon cancer screening that you can do at home. Several of these tests
have received FDA approval.

Who is eligible to use a colon cancer test at home?

A stool test looks for cancer or signs of cancer, even if someone doesn’t have any symptoms. Colorectal cancer screening starts at age 45. Some tests find early signs of colorectal cancer like pre-cancerous polyps, but all of the at-home tests help catch cancer early, when it’s easier to treat.

Those who are eligible for stool tests include:

  • Patients who are 45 years old or older.
  • Patients who are NOT experiencing any signs or symptoms.
  • People without family history of colorectal cancer or pre-cancerous polyps.
  • People without a personal history of colorectal cancer or pre-cancerous polyps.
  • People who do not have inflammatory bowel disease or a genetic condition associated with colorectal cancer.
  • Patients who have not undergone radiation of the abdomen or pelvis.

If you have experienced any of these above situations, you’ll need to be screened via colonoscopy.

Who is eligible to use a colon cancer test at home?

A stool test looks for cancer or signs of cancer, even if someone doesn’t have any symptoms. Colorectal cancer screening starts at age 45. Some tests find early signs of colorectal cancer like pre-cancerous polyps, but all of the at-home tests help catch cancer early, when it’s easier to treat.

Those who are eligible for stool tests include:

  • Patients who are 45 years old or older.
  • Patients who are NOT experiencing any signs or symptoms.
  • People without family history of colorectal cancer or pre-cancerous polyps.
  • People without a personal history of colorectal cancer or pre-cancerous polyps.
  • People who do not have inflammatory bowel disease or a genetic condition associated with colorectal cancer.
  • Patients who have not undergone radiation of the abdomen or pelvis.

If you have experienced any of these above situations, you’ll need to be screened via colonoscopy.

Stool based options

There are several types of stool tests that have received FDA approval:

This test looks for small amounts of blood or DNA markers associated with colorectal cancer. DNA in stool comes from cells in the colon and rectum lining that are shed as stool moves through the intestines.

One stool sample is needed, and it can be collected at home and then sent to a lab.

This test is repeated every 3 years, if normal.

If a test is positive, it doesn’t always mean cancer. But you need a colonoscopy within 90 days to find out why the first test was abnormal.

The FIT can identify small amounts of blood that are microscopic and difficult for you to see.

One stool sample is sufficient, and it can be collected at home.

This is an affordable choice, but you need to do the test every year if it’s normal.

If a test is positive, it doesn’t always mean you have cancer. But you need a colonoscopy within 90 days to find out why the first test was abnormal.

Stool is collected at home and sent to a lab, which looks for small amounts of blood. You’ll get home instructions for using the kit, a list of medicines and foods to avoid (like ibuprofen), and details on where to send it back when you’re done. Three stool samples are needed.

This test is no longer commonly used and has been mostly replaced by FIT.

Stool based options

There are several types of stool tests that have received FDA approval:

This test looks for small amounts of blood or DNA markers associated with colorectal cancer. DNA in stool comes from cells in the colon and rectum lining that are shed as stool moves through the intestines.

One stool sample is needed, and it can be collected at home and then sent to a lab.

This test is repeated every 3 years, if normal.

If a test is positive, it doesn’t always mean cancer. But you need a colonoscopy within 90 days to find out why the first test was abnormal.

The FIT can identify small amounts of blood that are microscopic and difficult for you to see.

One stool sample is sufficient, and it can be collected at home.

This is an affordable choice, but you need to do the test every year if it’s normal.

If a test is positive, it doesn’t always mean you have cancer. But you need a colonoscopy within 90 days to find out why the first test was abnormal.

Stool is collected at home and sent to a lab, which looks for small amounts of blood. You’ll get home instructions for using the kit, a list of medicines and foods to avoid (like ibuprofen), and details on where to send it back when you’re done. Three stool samples are needed.

This test is no longer commonly used and has been mostly replaced by FIT.

Choosing the right stool test for you

With both the mt-sDNA and FIT, patients collect stool samples at home. A kit is provided with step-by-step instructions. (Follow the instructions for the test you choose; they’re different.)

Get your doctor involved and review the results together. Both tests look for small amounts of blood in the stool sample provided. Both tests need patients to get a colonoscopy if the result is positive. Do not skip this step.

If your Cologuard test is negative, you will need to repeat the test in 3 years. If your FIT is negative, it should be repeated in 1 year.

Choosing the right stool test for you

With both the mt-sDNA and FIT, patients collect stool samples at home. A kit is provided with step-by-step instructions. (Follow the instructions for the test you choose; they’re different.)

Get your doctor involved and review the results together. Both tests look for small amounts of blood in the stool sample provided. Both tests need patients to get a colonoscopy if the result is positive. Do not skip this step.

If your Cologuard test is negative, you will need to repeat the test in 3 years. If your FIT is negative, it should be repeated in 1 year.

Pros and Cons

When thinking about doing a stool test for colon cancer, it’s important to think about the pros and cons:

Pros

Non-invasive and private

You can do colorectal cancer tests at home. You don’t need to go to a doctor’s office to perform them.

Convenient

You can collect your stool sample at a time that works best for you. You do not need to take time off work, nor will you be going under anesthesia, so there’s less hassle. There is also zero prep involved.

High Sensitivity

Stool tests are good at finding colorectal cancer and showing who doesn’t have colorectal cancer.

In general, mt-sDNA will detect 9 out of 10 cancers as a single-time test. FIT will detect 7/8 out of 10 cancers.

Cons

Handling Stool

You’ll get gloves and kits to keep things clean, but you still need to handle your poop.

Limited Preventive Ability

The FIT can only identify hemoglobin (blood), which will trigger a need for a follow-up colonoscopy. It cannot detect pre-cancerous polyps.

The mt-sDNA can detect pre-cancerous polyps, but not with the same rate or accuracy when compared to a colonoscopy. “Colonoscopy is 75%–93% sensitive for finding any type of polyp smaller than 6 mm … FIT-fecal DNA test proved a detection rate for high-grade dysplasia of 62%, which then fell to 42% for detecting any type of polyp.” (Source: JAMA Network)

Stool tests can indicate pre-cancerous or cancerous growths, but they can’t remove them during the same test. Stool tests can have more incorrect results (false positives) than colonoscopies. Stool tests can’t explain why there’s bleeding if they show a positive result.

Follow-up Colonoscopy Required

If the stool test results are positive/abnormal, a follow-up colonoscopy within 90 days is necessary to confirm the findings.

Frequent Testing Needed

Stool tests will need to be repeated more frequently. The mt-sDNA test needs to be repeated every 3 years, and the FIT needs to be repeated every 1 year.

Pros and Cons

When thinking about doing a stool test for colon cancer, it’s important to think about the pros and cons:

Pros

Non-invasive and private

You can do colorectal cancer tests at home. You don’t need to go to a doctor’s office to perform them.

Convenient

You can collect your stool sample at a time that works best for you. You do not need to take time off work, nor will you be going under anesthesia, so there’s less hassle. There is also zero prep involved.

High Sensitivity

Stool tests are good at finding colorectal cancer and showing who doesn’t have colorectal cancer.

In general, mt-sDNA will detect 9 out of 10 cancers as a single-time test. FIT will detect 7/8 out of 10 cancers.

Cons

Handling Stool

You’ll get gloves and kits to keep things clean, but you still need to handle your poop.

Limited Preventive Ability

The FIT can only identify hemoglobin (blood), which will trigger a need for a follow-up colonoscopy. It cannot detect pre-cancerous polyps.

The mt-sDNA can detect pre-cancerous polyps, but not with the same rate or accuracy when compared to a colonoscopy. “Colonoscopy is 75%–93% sensitive for finding any type of polyp smaller than 6 mm … FIT-fecal DNA test proved a detection rate for high-grade dysplasia of 62%, which then fell to 42% for detecting any type of polyp.” (Source: JAMA Network)

Stool tests can indicate pre-cancerous or cancerous growths, but they can’t remove them during the same test. Stool tests can have more incorrect results (false positives) than colonoscopies. Stool tests can’t explain why there’s bleeding if they show a positive result.

Follow-up Colonoscopy Required

If the stool test results are positive/abnormal, a follow-up colonoscopy within 90 days is necessary to confirm the findings.

Frequent Testing Needed

Stool tests will need to be repeated more frequently. The mt-sDNA test needs to be repeated every 3 years, and the FIT needs to be repeated every 1 year.

Common Stool Test Questions

What should I do if I want to use a stool test?2025-01-02T16:27:00+00:00

You can get a test online or at a drug store, but it’s best to speak with your doctor to choose the right colorectal cancer screening test for you. Your doctor can give you a trustworthy test, explain the results, and guide you on what to do next.

What causes a positive result?2025-01-02T16:25:54+00:00

Stool tests are used to identify small traces of blood in feces that are not visible to the naked eye. The tests cannot determine why or what may be causing the bleeding, but only that blood is present in your stool sample.

Besides looking for blood in the stool, the mt-sDNA test also checks for abnormal DNA. If it finds either, you may receive a positive test result. But does a positive stool test mean cancer? No, but you will need a follow-up colonoscopy to determine why the test was positive.

Will a colon cancer test from a drug store work?2025-01-11T03:38:26+00:00

If you obtain a stool test from a drug store or health fair, it will likely work. However, we highly recommend either obtaining the test from your doctor and/or getting your doctor involved right away.

We understand it may be more convenient and cost effective for you to buy and take the test on your own. If that’s the case, we recommend:

  • Carefully read and follow the directions.
  • Let your doctor’s office know you are taking the test (and which one).
  • Follow up with your doctor’s office so they know you’ve completed your screening. Make sure they get a copy of the result.
  • In the event of a positive result, schedule your follow-up colonoscopy within 90 days.
  • If your test result is negative, plan to test again soon. (Discuss with your doctor the best time frame for you.)
Will my insurance pay for my stool test for colorectal cancer screening?2025-01-02T16:25:21+00:00

For most patients, the at-home tests for colorectal cancer screening are covered by insurance. If the test result is abnormal and a follow-up colonoscopy is needed, patients with private insurance, Medicare, and most Medicaid patients should not have out-of-pocket costs. This is a recent change following extensive advocacy from Fight CRC and our partners.

Common Stool Test Questions

What should I do if I want to use a stool test?2025-01-02T16:27:00+00:00

You can get a test online or at a drug store, but it’s best to speak with your doctor to choose the right colorectal cancer screening test for you. Your doctor can give you a trustworthy test, explain the results, and guide you on what to do next.

What causes a positive result?2025-01-02T16:25:54+00:00

Stool tests are used to identify small traces of blood in feces that are not visible to the naked eye. The tests cannot determine why or what may be causing the bleeding, but only that blood is present in your stool sample.

Besides looking for blood in the stool, the mt-sDNA test also checks for abnormal DNA. If it finds either, you may receive a positive test result. But does a positive stool test mean cancer? No, but you will need a follow-up colonoscopy to determine why the test was positive.

Will a colon cancer test from a drug store work?2025-01-11T03:38:26+00:00

If you obtain a stool test from a drug store or health fair, it will likely work. However, we highly recommend either obtaining the test from your doctor and/or getting your doctor involved right away.

We understand it may be more convenient and cost effective for you to buy and take the test on your own. If that’s the case, we recommend:

  • Carefully read and follow the directions.
  • Let your doctor’s office know you are taking the test (and which one).
  • Follow up with your doctor’s office so they know you’ve completed your screening. Make sure they get a copy of the result.
  • In the event of a positive result, schedule your follow-up colonoscopy within 90 days.
  • If your test result is negative, plan to test again soon. (Discuss with your doctor the best time frame for you.)
Will my insurance pay for my stool test for colorectal cancer screening?2025-01-02T16:25:21+00:00

For most patients, the at-home tests for colorectal cancer screening are covered by insurance. If the test result is abnormal and a follow-up colonoscopy is needed, patients with private insurance, Medicare, and most Medicaid patients should not have out-of-pocket costs. This is a recent change following extensive advocacy from Fight CRC and our partners.