Clinical Trial Finder Search Results

About the Fight CRC Clinical Trial Finder

This Trial Finder is a one-stop place to find and learn more about high-impact clinical trials for colorectal cancer patients with advanced colon or rectal cancer. Originally created by the late Dr. Tom Marsilje as a curated spreadsheet of trials, the FightCRC’s Trial Finder is a resource to find research studies that are open in your geography, and for which you may be eligible. The current data is now for metastatic, stage IV patients with both MSS and MSI-H status. The list of trials here is sourced from the ClinicalTrials.gov website and curated with Comments and Helpful Links. The searches can be focused on immunotherapy-centered trials and narrowed to studies enrolling patients who already have received immunotherapies.

Medical Disclaimer

The information contained in this website is not intended to recommend the self management of health problems, medical conditions or wellness. It is not intended to endorse or recommend any particular type of medical treatment, physician or treatment facility. Should any reader have any health care related questions, promptly call or consult your physician or healthcare provider. The information contained in this website should NOT be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Fight Colorectal Cancer disclaims any liability based on information provided in this website.

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NCT ID	Title	Phase	Date Added	Location	Prior IO Allowed	CRC-directed	Status	Drugs	Tags
NCT ID NCT03950154	TitleStudy of Chemotherapy Combination With Autologous Cell Immunotherapy in the Recurrent and Metastatic Colorectal Cancer	Phase Phase 3	Date Added 2019-05-15	Location China	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs Bevacizumab Injection [Avastin], capecitabine, oxaliplatin, PD1-T cells	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03947385	TitleStudy of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions	Phase Phase 1, Phase 2	Date Added 2019-05-13	Location California, United States New York, United States North Carolina, United States Ohio, United States Pennsylvania, United States Tennessee, United States Texas, United States Australia Canada	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs Binimetinib, Crizotinib, IDE196	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03940820	TitleClinical Research of ROBO1 Specific CAR-NK Cells on Patients With Solid Tumors	Phase Phase 1/Phase 2	Date Added 2019-05-07	Location China	Prior IO Allowed No	CRC-directed No	Status Recruiting	Drugs ROBO1 CAR-NK cells	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03935893	TitleAdoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers	Phase Phase 2	Date Added 2019-05-02	Location Pennsylvania, United States	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs Fludarabine + Cyclophosphamide combination, Tumor Infiltrating Lymphocytes (TIL)	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID PG545 (pixatimod) in combination with nivolumab	TitlePG545 (pixatimod) in combination with nivolumab	Phase Phase 1	Date Added 2019-04-26	Location	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03925662	TitleMebendazole as Adjuvant Treatment for Colon Cancer	Phase Phase 3	Date Added 2019-04-24	Location Egypt	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs Folfox with avastin, Mebendazole	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03921684	TitleTrial of Nivolumab With FOLFOX After Chemoradiation in Rectal Cancer Patients	Phase Phase 2	Date Added 2019-04-19	Location Israel	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs capecitabine, mFOLFOX6, Nivolumab	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03911557	TitleDurvalumab and Tremelimumab Combination in Somatically Hypermutated Recurrent Solid Tumors	Phase Phase 2	Date Added 2019-04-11	Location Kentucky, United States	Prior IO Allowed No	CRC-directed No	Status Active, not recruiting	Drugs Durvalumab and Tremelimumab	Tags MSS/ MMRp
NCT ID NCT03874897	TitleChimeric Antigen Receptor T Cells Targeting claudin18.2 in Solid Tumors.	Phase Phase 1	Date Added 2019-03-14	Location China	Prior IO Allowed No	CRC-directed No	Status Recruiting	Drugs CAR-CLDN18.2 T-Cells, Chemotherapy, PD-1 Monoclonal Antibody	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03868228	TitlePIPAC for the Treatment of Colorectal Peritoneal Metastases	Phase Phase 1	Date Added 2019-03-11	Location United Kingdom	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs	Tags MSI-H/ MMRd, MSS/ MMRp

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