Clinical Trial Finder Search Results

About the Fight CRC Clinical Trial Finder

This Trial Finder is a one-stop place to find and learn more about high-impact clinical trials for colorectal cancer patients with advanced colon or rectal cancer. Originally created by the late Dr. Tom Marsilje as a curated spreadsheet of trials, the FightCRC’s Trial Finder is a resource to find research studies that are open in your geography, and for which you may be eligible. The current data is now for metastatic, stage IV patients with both MSS and MSI-H status. The list of trials here is sourced from the ClinicalTrials.gov website and curated with Comments and Helpful Links. The searches can be focused on immunotherapy-centered trials and narrowed to studies enrolling patients who already have received immunotherapies.

Medical Disclaimer

The information contained in this website is not intended to recommend the self management of health problems, medical conditions or wellness. It is not intended to endorse or recommend any particular type of medical treatment, physician or treatment facility. Should any reader have any health care related questions, promptly call or consult your physician or healthcare provider. The information contained in this website should NOT be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Fight Colorectal Cancer disclaims any liability based on information provided in this website.

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NCT ID	Title	Phase	Date Added	Location	Prior IO Allowed	CRC-directed	Status	Drugs	Tags
NCT ID NCT03867799	TitleiSCORE: Immunotherapy Sequencing in COlon and REctal Cancer	Phase Phase 2	Date Added 2019-03-08	Location United Kingdom	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs Nivolumab	Tags MSS/ MMRp
NCT ID NCT03865082	TitleStudy of Tilsotolimod in Combination With Nivolumab and Ipilimumab for the Treatment of Solid Tumors (ILLUMINATE-206)	Phase Phase 2	Date Added 2019-03-06	Location Arizona, United States California, United States Texas, United States	Prior IO Allowed No	CRC-directed No	Status Active, not recruiting	Drugs Ipilimumab, Nivolumab, Tilsotolimod, Opdivo, Yervoy	Tags MSS/ MMRp
NCT ID NCT03860272	TitleFc-Engineered Anti-CTLA-4 Monoclonal Antibody Botensilimab in Advanced Cancer	Phase Phase 1	Date Added 2019-03-01	Location Arizona, United States California, United States Colorado, United States Connecticut, United States Florida, United States Massachusetts, United States New York, United States Oregon, United States Texas, United States United Kingdom	Prior IO Allowed Yes	CRC-directed Yes	Status Active, not recruiting	Drugs Balstilimab, Botensilimab	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03851614	TitleBasket Combination Study of Inhibitors of DNA Damage Response, Angiogenesis and Programmed Death Ligand 1 in Patients With Advanced Solid Tumors	Phase Phase 2	Date Added 2019-02-22	Location Canada	Prior IO Allowed Yes	CRC-directed Yes	Status Active, not recruiting	Drugs Cediranib, durvalumab, Olaparib	Tags MSS/ MMRp
NCT ID NCT03844750	TitlePembrolizumab After Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver and Who Are Undergoing Liver Surgery	Phase Phase 2	Date Added 2019-02-18	Location California, United States	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs Pembrolizumab, Vactosertib, Keytruda	Tags MSS/ MMRp
NCT ID NCT03835949	TitleStudy of TJ004309 in Combination With Atezolizumab (Tecentriq(R)) in Patients With Advanced or Metastatic Cancer	Phase Phase 1	Date Added 2019-02-11	Location Alabama, United States Arizona, United States California, United States Texas, United States	Prior IO Allowed No	CRC-directed No	Status Active, not recruiting	Drugs Atezolizumab, TJ004309	Tags MSS/ MMRp
NCT ID NCT03832855	TitleAssessing the Immunogenicity of pING-hHER3FL	Phase Phase 1	Date Added 2019-02-06	Location North Carolina, United States	Prior IO Allowed Yes	CRC-directed No	Status Recruiting	Drugs pING-hHER3FL	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03829462	TitleAssessing a Regorafenib-irinotecan Combination Versus Regorafenib Alone in Metastatic Colorectal Cancer Patients	Phase Phase 3	Date Added 2019-02-04	Location France	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs Irinotecan, Regorafenib	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID LUMINESCENCE	TitleIpilimumab, Maraviroc and Nivolumab (LUMINESCENCE)	Phase Phase 1	Date Added 2019-01-25	Location	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs Ipilimumab, maraviroc, Nivolumab, Celsentri, Opdivo, Selzentry, Yervoy	Tags MSS/ MMRp
NCT ID NCT03796884	TitleLinaclotide in Treating Patients With Stages 0-3 Colorectal Cancer	Phase Phase 2	Date Added 2019-01-08	Location Pennsylvania, United States Washington, United States	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs Linaclotide	Tags MSS/ MMRp

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