Clinical Trial Finder Search Results

About the Fight CRC Clinical Trial Finder

This Trial Finder is a one-stop place to find and learn more about high-impact clinical trials for colorectal cancer patients with advanced colon or rectal cancer. Originally created by the late Dr. Tom Marsilje as a curated spreadsheet of trials, the FightCRC’s Trial Finder is a resource to find research studies that are open in your geography, and for which you may be eligible. The current data is now for metastatic, stage IV patients with both MSS and MSI-H status. The list of trials here is sourced from the ClinicalTrials.gov website and curated with Comments and Helpful Links. The searches can be focused on immunotherapy-centered trials and narrowed to studies enrolling patients who already have received immunotherapies.

Medical Disclaimer

The information contained in this website is not intended to recommend the self management of health problems, medical conditions or wellness. It is not intended to endorse or recommend any particular type of medical treatment, physician or treatment facility. Should any reader have any health care related questions, promptly call or consult your physician or healthcare provider. The information contained in this website should NOT be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Fight Colorectal Cancer disclaims any liability based on information provided in this website.

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NCT ID	Title	Phase	Date Added	Location	Prior IO Allowed	CRC-directed	Status	Drugs	Tags
NCT ID NCT03668431	TitleDabrafenib + Trametinib + PDR001 In Colorectal Cancer	Phase Phase 2	Date Added 2018-09-12	Location Massachusetts, United States	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs Dabrafenib, PDR001, Trametinib, Mekinist, Tafinlar	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03667170	TitleKN035 for dMMR/MSI-H Advanced Solid Tumors	Phase Phase 2	Date Added 2018-09-12	Location China	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs	Tags MSI-H/ MMRd
NCT ID NCT03658785	TitleImmunotherapy for the Treatment of Advanced Solid Tumor	Phase Phase 1	Date Added 2018-09-05	Location China	Prior IO Allowed Yes	CRC-directed No	Status Recruiting	Drugs Aldesleukin, Cyclophosphamide, Fludarabine, TIL	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03657641	TitleRegorafenib and Pembrolizumab in Treating Participants With Advanced or Metastatic Colorectal Cancer	Phase Phase 1	Date Added 2018-09-05	Location California, United States Florida, United States	Prior IO Allowed Yes	CRC-directed Yes	Status Active, not recruiting	Drugs Pembrolizumab, Regorafenib, Keytruda, Stivarga	Tags MSS/ MMRp
NCT ID NCT03650348	TitlePRS-343 in Combination With Atezolizumab in HER2-Positive Solid Tumors	Phase Phase 1	Date Added 2018-08-28	Location California, United States Louisiana, United States New York, United States Ohio, United States Texas, United States	Prior IO Allowed Yes	CRC-directed No	Status Active, not recruiting	Drugs PRS-343 in Combination with Atezolizumab, Tecentriq	Tags MSS/ MMRp
NCT ID NCT03638206	TitleAutologous CAR-T/TCR-T Cell Immunotherapy for Malignancies	Phase Phase 1/Phase 2	Date Added 2018-08-20	Location China	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs CAR-T cell immunotherapy	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03638297	TitlePD-1 Antibody Combined With COX Inhibitor in MSI-H/dMMR or High TMB Colorectal Cancer	Phase Phase 2	Date Added 2018-08-20	Location China	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs PD-1 antibody + cox inhibitor	Tags MSI-H/ MMRd
NCT ID NCT03626922	TitleStudy of Pembrolizumab With Pemetrexed and Oxaliplatin in Chemo-Refractory Metastatic Colorectal Cancer Patients	Phase Phase 1	Date Added 2018-08-13	Location Florida, United States Illinois, United States Michigan, United States Minnesota, United States Pennsylvania, United States	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs Dexamethasone, oxaliplatin, Pembrolizumab, Pemetrexed, Alimta, Eloxatin, Keytruda	Tags MSS/ MMRp
NCT ID NCT03608046	TitleAvelumab Combined With Cetuximab and Irinotecan for Treatment Refractory Metastatic Colorectal Microsatellite Stable Cancer	Phase Phase 2	Date Added 2018-07-31	Location Belgium	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs Avelumab, Cetuximab Injection, Irinotecan	Tags MSS/ MMRp
NCT ID NCT03600883	TitleA Phase 1/2, Study Evaluating the Safety, Tolerability, PK, and Efficacy of Sotorasib (AMG 510) in Subjects With Solid Tumors With a Specific KRAS Mutation (CodeBreaK 100)	Phase Phase 1, Phase 2	Date Added 2018-07-26	Location California, United States Colorado, United States Connecticut, United States Delaware, United States Florida, United States Georgia, United States Indiana, United States Maryland, United States Massachusetts, United States Michigan, United States Missouri, United States New York, United States North Carolina, United States Ohio, United States Pennsylvania, United States South Carolina, United States Tennessee, United States Texas, United States Utah, United States Virginia, United States Washington, United States Australia Austria Belgium Brazil Canada France Germany Greece Hungary Japan Korea, Republic of Portugal Romania Spain Switzerland	Prior IO Allowed Yes	CRC-directed No	Status Active, not recruiting	Drugs Anti PD-1/L1, Midazolam, Sotorasib	Tags MSS/ MMRp

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