Clinical Trial Finder Search Results

About the Fight CRC Clinical Trial Finder

This Trial Finder is a one-stop place to find and learn more about high-impact clinical trials for colorectal cancer patients with advanced colon or rectal cancer. Originally created by the late Dr. Tom Marsilje as a curated spreadsheet of trials, the FightCRC’s Trial Finder is a resource to find research studies that are open in your geography, and for which you may be eligible. The current data is now for metastatic, stage IV patients with both MSS and MSI-H status. The list of trials here is sourced from the ClinicalTrials.gov website and curated with Comments and Helpful Links. The searches can be focused on immunotherapy-centered trials and narrowed to studies enrolling patients who already have received immunotherapies.

Medical Disclaimer

The information contained in this website is not intended to recommend the self management of health problems, medical conditions or wellness. It is not intended to endorse or recommend any particular type of medical treatment, physician or treatment facility. Should any reader have any health care related questions, promptly call or consult your physician or healthcare provider. The information contained in this website should NOT be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Fight Colorectal Cancer disclaims any liability based on information provided in this website.

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NCT ID	Title	Phase	Date Added	Location	Prior IO Allowed	CRC-directed	Status	Drugs	Tags
NCT ID NCT03599765	TitleSystemic Therapy With or Without Local Consolidative Therapy in Treating Patients With Oligometastatic Solid Tumor	Phase Phase 2	Date Added 2018-07-26	Location Arizona, United States Arkansas, United States Hawaii, United States Michigan, United States New Jersey, United States Ohio, United States Texas, United States	Prior IO Allowed Yes	CRC-directed No	Status Active, not recruiting	Drugs	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03577665	TitleCurative Proton Beam Therapy for Patients With Liver Metastasis of Colorectal Cancer	Phase Not Applicable	Date Added 2018-07-05	Location Korea, Republic of	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03568058	TitlePersonalized Immunotherapy in Adults With Advanced Cancers Immunotherapy in Adults With Advanced Cancers	Phase Phase 1	Date Added 2018-06-26	Location California, United States	Prior IO Allowed Yes	CRC-directed No	Status Active, not recruiting	Drugs Pembrolizumab, personalized vaccine, Keytruda	Tags MSS/ MMRp
NCT ID NCT03566355	TitleCurative Proton Beam Therapy for Patients With Lung Metastasis of Colorectal Cancer	Phase Not Applicable	Date Added 2018-06-25	Location Korea, Republic of	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03547999	TitleA Trial of Perioperative CV301 Vaccination in Combination With Nivolumab and Systemic Chemotherapy for Metastatic CRC	Phase Phase 2	Date Added 2018-06-06	Location California, United States Florida, United States Kansas, United States New Jersey, United States Ohio, United States Oregon, United States	Prior IO Allowed Yes	CRC-directed Yes	Status Active, not recruiting	Drugs FPV-CV301, mFOLFOX6, MVA-BN-CV301, Nivolumab	Tags MSS/ MMRp
NCT ID NCT03545815	TitleStudy of CRISPR-Cas9 Mediated PD-1 and TCR Gene-knocked Out Mesothelin-directed CAR-T Cells in Patients With Mesothelin Positive Multiple Solid Tumors.	Phase Phase 1	Date Added 2018-06-04	Location China	Prior IO Allowed Yes	CRC-directed No	Status Recruiting	Drugs anti-mesothelin CAR-T cells	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03530397	TitleA Study to Evaluate MEDI5752 in Subjects With Advanced Solid Tumors	Phase Phase 1	Date Added 2018-05-21	Location Michigan, United States New York, United States North Carolina, United States Rhode Island, United States Tennessee, United States Virginia, United States Australia France Italy Korea, Republic of Netherlands Portugal Spain Taiwan	Prior IO Allowed Yes	CRC-directed No	Status Active, not recruiting	Drugs Carboplatin, MEDI5752, Pembrolizumab, Pemetrexed, Alimta, Imfinzi, Keytruda, Paraplatin	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03519412	TitlePembrolizumab in MMR-Proficient Metastatic Colorectal Cancer Pharmacologically Primed to Trigger Hypermutation Status	Phase Phase 2	Date Added 2018-05-09	Location Italy	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs pembrolizumab (treatment), temozolomide (induction),, Keytruda, Temodar	Tags MSS/ MMRp
NCT ID NCT03502733	TitleTesting the Combination of Copanlisib, Nivolumab and Ipilimumab in Patients With Advanced Cancer and Lymphoma	Phase Phase 1	Date Added 2018-04-19	Location Maryland, United States Texas, United States	Prior IO Allowed Yes	CRC-directed No	Status Active, not recruiting	Drugs Copanlisib, Ipilimumab, Nivolumab, Aliqopa, Opdivo	Tags MSS/ MMRp
NCT ID NCT03494946	TitleLiver Transplantation Compared to Chemotherapy in Patients With ColoRectal Cancer	Phase Not Applicable	Date Added 2018-04-11	Location Norway	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs Chemotherapy	Tags MSI-H/ MMRd, MSS/ MMRp

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