Clinical Trial Finder Search Results

About the Fight CRC Clinical Trial Finder

This Trial Finder is a one-stop place to find and learn more about high-impact clinical trials for colorectal cancer patients with advanced colon or rectal cancer. Originally created by the late Dr. Tom Marsilje as a curated spreadsheet of trials, the FightCRC’s Trial Finder is a resource to find research studies that are open in your geography, and for which you may be eligible. The current data is now for metastatic, stage IV patients with both MSS and MSI-H status. The list of trials here is sourced from the ClinicalTrials.gov website and curated with Comments and Helpful Links. The searches can be focused on immunotherapy-centered trials and narrowed to studies enrolling patients who already have received immunotherapies.

Medical Disclaimer

The information contained in this website is not intended to recommend the self management of health problems, medical conditions or wellness. It is not intended to endorse or recommend any particular type of medical treatment, physician or treatment facility. Should any reader have any health care related questions, promptly call or consult your physician or healthcare provider. The information contained in this website should NOT be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Fight Colorectal Cancer disclaims any liability based on information provided in this website.

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NCT ID	Title	Phase	Date Added	Location	Prior IO Allowed	CRC-directed	Status	Drugs	Tags
NCT ID NCT05299840	TitleImpact of Using the Oncogramme(R) Device to Select the First Line of Treatment for Patients With Metastatic Colorectal Cancer	Phase Not Applicable	Date Added 2022-03-29	Location France	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT05292417	TitleRadiotherapy in Combination With Sintilimab，GM-CSF and Fruquintinib in Patients With MSS mCRC	Phase Phase 2	Date Added 2022-03-23	Location China	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs Fruquintinib, GM-CSF, Sintilimab	Tags MSS/ MMRp
NCT ID NCT05291156	TitleCAVE-2 GOIM Study: a Clinical Study of the Combination of Avelumab Plus Cetuximab as Rechallenge Strategy	Phase Phase 2	Date Added 2022-03-22	Location Italy	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs Avelumab, cetuximab	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT05286814	TitleM9241 in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer or Intrahepatic Cholangiocarcinoma	Phase Phase 2	Date Added 2022-03-18	Location Maryland, United States	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs	Tags MSS/ MMRp
NCT ID NCT05277051	TitleFirst-Time-in-Human Study of GSK4381562 in Participants With Advanced Solid Tumors	Phase Phase 1	Date Added 2022-03-14	Location California, United States North Carolina, United States Oklahoma, United States Pennsylvania, United States Texas, United States Utah, United States Australia Canada China France Japan South Korea Spain United Kingdom	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs Dostarlimab, GSK4381562	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT05243862	TitleSafety and Activity of PolyPEPI1018 Plus Atezolizumab in Colorectal Cancer.	Phase Phase 2	Date Added 2022-02-17	Location Arizona, United States Florida, United States Minnesota, United States	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs Atezolizumab, PolyPEPI1018, Tecentriq	Tags MSS/ MMRp
NCT ID NCT05239741	TitleStudy of Pembrolizumab (MK-3475) Versus Chemotherapy in Chinese Participants With Stage IV Colorectal Cancer (MK-3475-C66)	Phase Phase 3	Date Added 2022-02-15	Location China	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs 5-Fluorouracil, Irinotecan, Leucovorin, oxaliplatin	Tags MSI-H/ MMRd
NCT ID NCT05217446	TitleA Study of Encorafenib Plus Cetuximab Taken Together With Pembrolizumab Compared to Pembrolizumab Alone in People With Previously Untreated Metastatic Colorectal Cancer ( SEAMARK )	Phase Phase 2	Date Added 2022-02-01	Location Arizona, United States California, United States Florida, United States Tennessee, United States Texas, United States Australia Belgium Canada Czechia Denmark France Germany Italy Netherlands Norway Poland Slovakia Spain United Kingdom	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs encorafenib, Braftovi, Erbitux, Keytruda	Tags MSI-H/ MMRd
NCT ID NCT05215574	TitleStudy of NGM831 as Monotherapy and in Combination With Pembrolizumab in Advanced or Metastatic Solid Tumors	Phase Phase 1	Date Added 2022-01-31	Location Arizona, United States California, United States Florida, United States Michigan, United States New York, United States Oklahoma, United States Texas, United States	Prior IO Allowed Yes	CRC-directed Yes	Status Active, not recruiting	Drugs NGM831, NGM831 plus pembrolizumab	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT05213195	TitleNKG2D CAR-NK Cell Therapy in Patients With Refractory Metastatic Colorectal Cancer	Phase Phase 1	Date Added 2022-01-28	Location China	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs NKG2D CAR-NK	Tags MSI-H/ MMRd, MSS/ MMRp

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