Clinical Trial Finder Search Results

About the Fight CRC Clinical Trial Finder

This Trial Finder is a one-stop place to find and learn more about high-impact clinical trials for colorectal cancer patients with advanced colon or rectal cancer. Originally created by the late Dr. Tom Marsilje as a curated spreadsheet of trials, the FightCRC’s Trial Finder is a resource to find research studies that are open in your geography, and for which you may be eligible. The current data is now for metastatic, stage IV patients with both MSS and MSI-H status. The list of trials here is sourced from the ClinicalTrials.gov website and curated with Comments and Helpful Links. The searches can be focused on immunotherapy-centered trials and narrowed to studies enrolling patients who already have received immunotherapies.

Medical Disclaimer

The information contained in this website is not intended to recommend the self management of health problems, medical conditions or wellness. It is not intended to endorse or recommend any particular type of medical treatment, physician or treatment facility. Should any reader have any health care related questions, promptly call or consult your physician or healthcare provider. The information contained in this website should NOT be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Fight Colorectal Cancer disclaims any liability based on information provided in this website.

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NCT ID	Title	Phase	Date Added	Location	Prior IO Allowed	CRC-directed	Status	Drugs	Tags
NCT ID NCT04708470	TitlePhase I/II Trial of the Combination of Bintrafusp Alfa (M7824), Entinostat and NHS-IL12 (M9241) in Patients With Advanced Cancer	Phase Phase 1, Phase 2	Date Added 2021-01-14	Location Maryland, United States	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs Bintrafusp alfa, Entinostat, NHS-IL12	Tags MSS/ MMRp
NCT ID NCT04362839	TitleRegorafenib, Ipilimumab and Nivolumab for the Treatment of Chemotherapy Resistant Microsatellite Stable Metastatic Colorectal Cancer	Phase Phase 1	Date Added 2020-04-27	Location California, United States	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs Ipilimumab, Nivolumab, Regorafenib, Opdivo, Stivarga, Yervoy	Tags MSS/ MMRp
NCT ID NCT04092673	TitleStudy of eFT226 in Subjects With Selected Advanced Solid Tumor Malignancies	Phase Phase 1	Date Added 2019-09-17	Location California, United States Michigan, United States Nevada, United States New Jersey, United States New York, United States Ohio, United States Texas, United States Virginia, United States	Prior IO Allowed No	CRC-directed No	Status Recruiting	Drugs eFT226, eFT226	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03796884	TitleLinaclotide in Treating Patients With Stages 0-3 Colorectal Cancer	Phase Phase 2	Date Added 2019-01-08	Location Pennsylvania, United States Washington, United States	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs Linaclotide	Tags MSS/ MMRp
NCT ID NCT02864485	TitleLiving Donor Liver Transplantation for Unresectable Colorectal Cancer Liver Metastases	Phase Not Applicable	Date Added 2016-08-12	Location Canada	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT04050709	TitleQUILT 3.064: PD-L1 t-haNK In Subjects With Locally Advanced Or Metastatic Solid Cancers	Phase Phase 1	Date Added 2019-08-08	Location California, United States	Prior IO Allowed No	CRC-directed No	Status Active, not recruiting	Drugs PD-L1 t-haNK	Tags MSS/ MMRp
NCT ID NCT02675946	TitleCGX1321 in Subjects With Advanced Solid Tumors and CGX1321 With Pembrolizumab or Encorafenib + Cetuximab in Subjects With Advanced GI Tumors (Keynote 596)	Phase Phase 1	Date Added 2016-02-05	Location California, United States Colorado, United States Connecticut, United States District of Columbia, United States Florida, United States Georgia, United States Hawaii, United States Illinois, United States Indiana, United States Maryland, United States Massachusetts, United States Nebraska, United States New Jersey, United States North Carolina, United States Pennsylvania, United States South Dakota, United States Tennessee, United States Texas, United States Washington, United States Wisconsin, United States Taiwan	Prior IO Allowed No	CRC-directed No	Status Recruiting	Drugs cetuximab, CGX1321, encorafenib, Pembrolizumab, Keytruda	Tags MSS/ MMRp
NCT ID NCT03608046	TitleAvelumab Combined With Cetuximab and Irinotecan for Treatment Refractory Metastatic Colorectal Microsatellite Stable Cancer	Phase Phase 2	Date Added 2018-07-31	Location Belgium	Prior IO Allowed No	CRC-directed Yes	Status Recruiting	Drugs Avelumab, Cetuximab Injection, Irinotecan	Tags MSS/ MMRp
NCT ID NCT03626922	TitleStudy of Pembrolizumab With Pemetrexed and Oxaliplatin in Chemo-Refractory Metastatic Colorectal Cancer Patients	Phase Phase 1	Date Added 2018-08-13	Location Florida, United States Illinois, United States Michigan, United States Minnesota, United States Pennsylvania, United States	Prior IO Allowed No	CRC-directed Yes	Status Active, not recruiting	Drugs Dexamethasone, oxaliplatin, Pembrolizumab, Pemetrexed, Alimta, Eloxatin, Keytruda	Tags MSS/ MMRp
NCT ID NCT03013218	TitleA Study of Evorpacept (ALX148) in Patients With Advanced Solid Tumors and Lymphoma (ASPEN-01)	Phase Phase 1	Date Added 2017-01-06	Location Colorado, United States Connecticut, United States Massachusetts, United States Michigan, United States Washington, United States Korea, Republic of	Prior IO Allowed No	CRC-directed No	Status Active, not recruiting	Drugs 5-FU + Cisplatin, Evorpacept (ALX148), Pembrolizumab, Ramucirumab + Paclitaxel, Rituximab, Trastuzumab	Tags MSS/ MMRp

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