Clinical Trial Finder Search Results

About the Fight CRC Clinical Trial Finder

This Trial Finder is a one-stop place to find and learn more about high-impact clinical trials for colorectal cancer patients with advanced colon or rectal cancer. Originally created by the late Dr. Tom Marsilje as a curated spreadsheet of trials, the FightCRC’s Trial Finder is a resource to find research studies that are open in your geography, and for which you may be eligible. The current data is now for metastatic, stage IV patients with both MSS and MSI-H status. The list of trials here is sourced from the ClinicalTrials.gov website and curated with Comments and Helpful Links. The searches can be focused on immunotherapy-centered trials and narrowed to studies enrolling patients who already have received immunotherapies.

Medical Disclaimer

The information contained in this website is not intended to recommend the self management of health problems, medical conditions or wellness. It is not intended to endorse or recommend any particular type of medical treatment, physician or treatment facility. Should any reader have any health care related questions, promptly call or consult your physician or healthcare provider. The information contained in this website should NOT be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Fight Colorectal Cancer disclaims any liability based on information provided in this website.

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NCT ID	Title	Phase	Date Added	Location	Prior IO Allowed	CRC-directed	Status	Drugs	Tags
NCT ID NCT04111172	TitleA Vaccine (Ad5.F35-hGCC-PADRE) for the Treatment of Gastrointestinal Adenocarcinoma	Phase Phase 2	Date Added 2019-10-01	Location Pennsylvania, United States	Prior IO Allowed Yes	CRC-directed Yes	Status Active, not recruiting	Drugs Adenovirus 5/F35-Human Guanylyl Cyclase C-PADRE	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03566355	TitleCurative Proton Beam Therapy for Patients With Lung Metastasis of Colorectal Cancer	Phase Not Applicable	Date Added 2018-06-25	Location Korea, Republic of	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT04185883	TitleSotorasib Activity in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation (CodeBreak 101)	Phase Phase 1	Date Added 2019-12-04	Location Arizona, United States California, United States Colorado, United States Connecticut, United States Florida, United States Georgia, United States Illinois, United States Indiana, United States Iowa, United States Maryland, United States Michigan, United States Missouri, United States New York, United States North Carolina, United States Ohio, United States Oregon, United States Pennsylvania, United States South Carolina, United States South Dakota, United States Tennessee, United States Texas, United States Utah, United States Virginia, United States Washington, United States Australia Austria Belgium Canada Germany Italy Japan Korea, Republic of Netherlands Spain Taiwan United Kingdom	Prior IO Allowed Yes	CRC-directed No	Status Recruiting	Drugs afatinib, AMG 404, Atezolizumab, carboplatin, pemetrexed, docetaxel, everolimus, FOLFIRI, FOLFOX, MVASI® (bevacizumab-awwb), palbociclib, panitumumab, Pembrolizumab, RMC-4630, Sotorasib, TNO155, Trametinib	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT03740256	TitleBinary Oncolytic Adenovirus in Combination With HER2-Specific Autologous CAR VST, Advanced HER2 Positive Solid Tumors	Phase Phase 1	Date Added 2018-11-14	Location Texas, United States	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs CAdVEC	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT02453620	TitleEntinostat, Nivolumab, and Ipilimumab in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery or Locally Advanced or Metastatic HER2-Negative Breast Cancer	Phase Phase 1	Date Added 2015-05-25	Location California, United States Connecticut, United States Maryland, United States Pennsylvania, United States	Prior IO Allowed Yes	CRC-directed No	Status Active, not recruiting	Drugs Entinostat, Ipilimumab, Nivolumab, Opdivo, Yervoy	Tags MSS/ MMRp
NCT ID NCT03170960	TitleStudy of Cabozantinib in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid Tumors	Phase Phase 1	Date Added 2017-05-31	Location Arizona, United States California, United States Colorado, United States Connecticut, United States District of Columbia, United States Florida, United States Georgia, United States Illinois, United States Kansas, United States Kentucky, United States Louisiana, United States Massachusetts, United States Michigan, United States Minnesota, United States Missouri, United States Nebraska, United States Nevada, United States New Jersey, United States New York, United States Ohio, United States Oklahoma, United States Oregon, United States Pennsylvania, United States South Carolina, United States Texas, United States Utah, United States Virginia, United States Australia Belgium France Germany Italy Netherlands Spain United Kingdom	Prior IO Allowed Yes	CRC-directed Yes	Status Active, not recruiting	Drugs Atezolizumab, Cabozantinib	Tags MSS/ MMRp
NCT ID NCT03600883	TitleA Phase 1/2, Study Evaluating the Safety, Tolerability, PK, and Efficacy of Sotorasib (AMG 510) in Subjects With Solid Tumors With a Specific KRAS Mutation (CodeBreaK 100)	Phase Phase 1, Phase 2	Date Added 2018-07-26	Location California, United States Colorado, United States Connecticut, United States Delaware, United States Florida, United States Georgia, United States Indiana, United States Maryland, United States Massachusetts, United States Michigan, United States Missouri, United States New York, United States North Carolina, United States Ohio, United States Pennsylvania, United States South Carolina, United States Tennessee, United States Texas, United States Utah, United States Virginia, United States Washington, United States Australia Austria Belgium Brazil Canada France Germany Greece Hungary Japan Korea, Republic of Portugal Romania Spain Switzerland	Prior IO Allowed Yes	CRC-directed No	Status Active, not recruiting	Drugs Anti PD-1/L1, Midazolam, Sotorasib	Tags MSS/ MMRp
NCT ID PG545 (pixatimod) in combination with nivolumab	TitlePG545 (pixatimod) in combination with nivolumab	Phase Phase 1	Date Added 2019-04-26	Location	Prior IO Allowed Yes	CRC-directed Yes	Status Recruiting	Drugs	Tags MSI-H/ MMRd, MSS/ MMRp
NCT ID NCT02668770	TitleIpilimumab (Immunotherapy) and MGN1703 (TLR Agonist) in Patients With Advanced Solid Malignancies	Phase Phase 1	Date Added 2016-01-29	Location Texas, United States	Prior IO Allowed Yes	CRC-directed No	Status Active, not recruiting	Drugs Ipilimumab, MGN1703	Tags MSS/ MMRp
NCT ID NCT02285816	TitleMG1 Maraba/MAGE-A3, With and Without Adenovirus Vaccine With Transgenic MAGE-A3 Insertion in Incurable MAGE-A3-Expressing Solid Tumours	Phase Phase 1, Phase 2	Date Added 2014-11-07	Location Canada	Prior IO Allowed Yes	CRC-directed No	Status Active, not recruiting	Drugs AdMA3, MG1MA3	Tags MSS/ MMRp

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